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Patch classification models based on deep learning have been utilized in whole-slide images (WSI) of H&E-stained tissue samples to assist pathologists in grading follicular lymphoma patients. However, these approaches still require…

Determining the 3D structures of biological molecules is a key problem for both biology and medicine. Electron Cryomicroscopy (Cryo-EM) is a promising technique for structure estimation which relies heavily on computational methods to…

Machine Learning · Statistics 2015-01-29 Ali Punjani , Marcus A. Brubaker

Background: Single-particle cryo-electron microscopy (cryo-EM) has become a popular tool for structural determination of biological macromolecular complexes. High-resolution cryo-EM reconstruction often requires hundreds of thousands of…

Data Analysis, Statistics and Probability · Physics 2017-09-05 Yanan Zhu , Qi Ouyang , Youdong Mao

Optimal design for model training is a critical topic in machine learning. Active Learning aims at obtaining improved models by querying samples with maximum uncertainty according to the estimation model for artificially labeling; this has…

Remote sensing data is crucial for applications ranging from monitoring forest fires and deforestation to tracking urbanization. Most of these tasks require dense pixel-level annotations for the model to parse visual information from…

Computer Vision and Pattern Recognition · Computer Science 2021-10-18 Shasvat Desai , Debasmita Ghose

Efficient materials discovery requires reducing costly first-principles calculations for training machine-learned interatomic potentials (MLIPs). We develop an active learning (AL) framework that iteratively selects informative structures…

Machine Learning · Computer Science 2026-01-22 Mohammed Azeez Khan , Aaron D'Souza , Vijay Choyal

Semi-supervised learning has become increasingly popular in medical image segmentation due to its ability to leverage large amounts of unlabeled data to extract additional information. However, most existing semi-supervised segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-07-13 Shengbo Gao , Ziji Zhang , Jiechao Ma , Zihao Li , Shu Zhang

Image recognition techniques heavily rely on abundant labeled data, particularly in medical contexts. Addressing the challenges associated with obtaining labeled data has led to the prominence of self-supervised learning and semi-supervised…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Hao Feng , Yuanzhe Jia , Ruijia Xu , Mukesh Prasad , Ali Anaissi , Ali Braytee

Classification is an important task in many fields including biomedical research and machine learning. Traditionally, a classification rule is constructed based a bunch of labeled data. Recently, due to technological innovation and…

Methodology · Statistics 2014-06-19 Jing Wang , Eunsik Park , Yuan-chin Ivan Chang

Active learning is a promising paradigm to reduce the labeling cost by strategically requesting labels to improve model performance. However, existing active learning methods often rely on expensive acquisition function to compute,…

Machine Learning · Computer Science 2023-10-27 Zixin Ding , Si Chen , Ruoxi Jia , Yuxin Chen

Deep neural networks have reached high accuracy on object detection but their success hinges on large amounts of labeled data. To reduce the labels dependency, various active learning strategies have been proposed, typically based on the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-30 Ismail Elezi , Zhiding Yu , Anima Anandkumar , Laura Leal-Taixe , Jose M. Alvarez

It is well known that the success of deep neural networks is greatly attributed to large-scale labeled datasets. However, it can be extremely time-consuming and laborious to collect sufficient high-quality labeled data in most practical…

Computer Vision and Pattern Recognition · Computer Science 2022-02-18 Yao Yao , Junyi Shen , Jin Xu , Bin Zhong , Li Xiao

Pre-training a recognition model with contrastive learning on a large dataset of unlabeled data has shown great potential to boost the performance of a downstream task, e.g., image classification. However, in domains such as medical…

Computer Vision and Pattern Recognition · Computer Science 2021-08-24 Jizong Peng , Ping Wang , Chrisitian Desrosiers , Marco Pedersoli

Biomedical image segmentation is critical for precise structure delineation and downstream analysis. Traditional methods often struggle with noisy data, while deep learning models such as U-Net have set new benchmarks in segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Shuo Zhao , Yu Zhou , Jianxu Chen

High accuracy medical image classification can be limited by the costs of acquiring more data as well as the time and expertise needed to label existing images. In this paper, we apply active learning to medical image classification, a…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Emma Slade , Kim M. Branson

Which volume to annotate next is a challenging problem in building medical imaging datasets for deep learning. One of the promising methods to approach this question is active learning (AL). However, AL has been a hard nut to crack in terms…

Computer Vision and Pattern Recognition · Computer Science 2022-09-15 Vishwesh Nath , Dong Yang , Holger R. Roth , Daguang Xu

Recently, deep learning-based methods achieved promising performance in nuclei detection and classification applications. However, training deep learning-based methods requires a large amount of pixel-wise annotated data, which is…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Nazanin Moradinasab , Rebecca A. Deaton , Laura S. Shankman , Gary K. Owens , Donald E. Brown

Supervised machine learning based state-of-the-art computer vision techniques are in general data hungry and pose the challenges of not having adequate computing resources and of high costs involved in human labeling efforts. Training data…

Computer Vision and Pattern Recognition · Computer Science 2018-05-30 Vishal Kaushal , Anurag Sahoo , Khoshrav Doctor , Narasimha Raju , Suyash Shetty , Pankaj Singh , Rishabh Iyer , Ganesh Ramakrishnan

Scanning transmission electron microscopy (STEM) is now the primary tool for exploring functional materials on the atomic level. Often, features of interest are highly localized in specific regions in the material, such as ferroelectric…

Materials Science · Physics 2021-08-11 Nicole Creange , Ondrej Dyck , Rama K. Vasudevan , Maxim Ziatdinov , Sergei V. Kalinin

Semi-supervised classification based on active learning has made significant progress, but the existing methods often ignore the uncertainty estimation (or reliability) of the prediction results during the learning process, which makes it…

Machine Learning · Computer Science 2025-05-28 Shenkai Zhao , Xinao Zhang , Lipeng Pan , Xiaobin Xu , Danilo Pelusi