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Cryo-electron microscopy (cryo-EM) remains pivotal in structural biology, yet the task of protein particle picking, integral for 3D protein structure construction, is laden with manual inefficiencies. While recent AI tools such as Topaz and…

Computer Vision and Pattern Recognition · Computer Science 2023-11-29 Fei He , Zhiyuan Yang , Mingyue Gao , Biplab Poudel , Newgin Sam Ebin Sam Dhas , Rajan Gyawali , Ashwin Dhakal , Jianlin Cheng , Dong Xu

Training deep object detectors demands expensive bounding box annotation. Active learning (AL) is a promising technique to alleviate the annotation burden. Performing AL at box-level for object detection, i.e., selecting the most…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Jingyi Liao , Xun Xu , Chuan-Sheng Foo , Lile Cai

Consider a sequential active learning problem where, at each round, an agent selects a batch of unlabeled data points, queries their labels and updates a binary classifier. While there exists a rich body of work on active learning in this…

Machine Learning · Computer Science 2020-05-26 Abbas Kazerouni , Qi Zhao , Jing Xie , Sandeep Tata , Marc Najork

Deep learning-based human activity recognition (HAR) methods have shown great promise in the applications of smart healthcare systems and wireless body sensor network (BSN). Despite their demonstrated performance in laboratory settings, the…

Human-Computer Interaction · Computer Science 2023-03-28 Baichun Wei , Chunzhi Yi , Qi Zhang , Haiqi Zhu , Jianfei Zhu , Feng Jiang

Efficient label acquisition processes are key to obtaining robust classifiers. However, data labeling is often challenging and subject to high levels of label noise. This can arise even when classification targets are well defined, if…

Artificial Intelligence · Computer Science 2018-08-22 Olivier Deiss , Siddharth Biswal , Jing Jin , Haoqi Sun , M. Brandon Westover , Jimeng Sun

The past decade's "cryoEM revolution" has produced exponential growth in high-resolution structural data through advances in cryogenic electron microscopy (cryoEM) and tomography (cryoET). Deep learning integration into structural…

Quantitative Methods · Quantitative Biology 2025-07-29 Brady K. Zhou , Jason J. Hu , Jane K. J. Lee , Z. Hong Zhou , Demetri Terzopoulos

In semi-supervised learning, methods that rely on confidence learning to generate pseudo-labels have been widely proposed. However, increasing research finds that when faced with noisy and biased data, the model's representation network is…

Computer Vision and Pattern Recognition · Computer Science 2024-04-29 Yanbiao Ma , Licheng Jiao , Fang Liu , Lingling Li , Shuyuan Yang , Xu Liu

Modern machine learning pipelines, in particular those based on deep learning (DL) models, require large amounts of labeled data. For classification problems, the most common learning paradigm consists of presenting labeled examples during…

Computer Vision and Pattern Recognition · Computer Science 2022-11-30 Jacopo Teneggi , Paul H. Yi , Jeremias Sulam

The development of X-Ray microscopy (XRM) technology has enabled non-destructive inspection of semiconductor structures for defect identification. Deep learning is widely used as the state-of-the-art approach to perform visual analysis…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Lile Cai , Ramanpreet Singh Pahwa , Xun Xu , Jie Wang , Richard Chang , Lining Zhang , Chuan-Sheng Foo

Deep learning for clinical applications is subject to stringent performance requirements, which raises a need for large labeled datasets. However, the enormous cost of labeling medical data makes this challenging. In this paper, we build a…

Computer Vision and Pattern Recognition · Computer Science 2018-09-11 Weicheng Kuo , Christian Häne , Esther Yuh , Pratik Mukherjee , Jitendra Malik

Active Learning is a very common yet powerful framework for iteratively and adaptively sampling subsets of the unlabeled sets with a human in the loop with the goal of achieving labeling efficiency. Most real world datasets have imbalance…

Computer Vision and Pattern Recognition · Computer Science 2022-06-20 Suraj Kothawade , Shivang Chopra , Saikat Ghosh , Rishabh Iyer

Active learning (AL) is a machine learning algorithm that can achieve greater accuracy with fewer labeled training instances, for having the ability to ask oracles to label the most valuable unlabeled data chosen iteratively and…

Machine Learning · Computer Science 2022-09-30 Ruoyu Wang

Cryogenic Electron Tomography (CryoET) is a useful imaging technology in structural biology that is hindered by its need for manual annotations, especially in particle picking. Recent works have endeavored to remedy this issue with few-shot…

Quantitative Methods · Quantitative Biology 2024-07-10 Yizhou Zhao , Hengwei Bian , Michael Mu , Mostofa R. Uddin , Zhenyang Li , Xiang Li , Tianyang Wang , Min Xu

A major challenge that prevents the training of DL models is the limited availability of accurately labeled data. This shortcoming is highlighted in areas where data annotation becomes a time-consuming and error-prone task. In this regard,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 David Aparco-Cardenas , Jancarlo F. Gomes , Alexandre X. Falcão , Pedro J. de Rezende

Active learning (AL) techniques reduce labeling costs for training neural machine translation (NMT) models by selecting smaller representative subsets from unlabeled data for annotation. Diversity sampling techniques select heterogeneous…

Computation and Language · Computer Science 2024-12-19 Abdul Hameed Azeemi , Ihsan Ayyub Qazi , Agha Ali Raza

CNN visualization and interpretation methods, like class-activation maps (CAMs), are typically used to highlight the image regions linked to class predictions. These models allow to simultaneously classify images and extract class-dependent…

Computer Vision and Pattern Recognition · Computer Science 2020-11-17 Soufiane Belharbi , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

Deep learning approaches achieve state-of-the-art performance for classifying radiology images, but rely on large labelled datasets that require resource-intensive annotation by specialists. Both semi-supervised learning and active learning…

Computer Vision and Pattern Recognition · Computer Science 2022-09-07 Shafa Balaram , Cuong M. Nguyen , Ashraf Kassim , Pavitra Krishnaswamy

Semi-supervised techniques have removed the barriers of large scale labelled set by exploiting unlabelled data to improve the performance of a model. In this paper, we propose a semi-supervised deep multi-task classification and…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 R. M. Saad Bashir , Talha Qaiser , Shan E Ahmed Raza , Nasir M. Rajpoot

Label scarcity has been a long-standing issue for biomedical image segmentation, due to high annotation costs and professional requirements. Recently, active learning (AL) strategies strive to reduce annotation costs by querying a small…

Image and Video Processing · Electrical Eng. & Systems 2022-11-02 Ziyuan Zhao , Wenjing Lu , Zeng Zeng , Kaixin Xu , Bharadwaj Veeravalli , Cuntai Guan

Deep learning methods typically depend on the availability of labeled data, which is expensive and time-consuming to obtain. Active learning addresses such effort by prioritizing which samples are best to annotate in order to maximize the…

Computer Vision and Pattern Recognition · Computer Science 2023-01-18 Mélanie Gaillochet , Christian Desrosiers , Hervé Lombaert