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Epidemiological models can not only be used to forecast the course of a pandemic like COVID-19, but also to propose and design non-pharmaceutical interventions such as school and work closing. In general, the design of optimal policies…

Optimization and Control · Mathematics 2023-04-06 Jan-Hendrik Niemann , Samuel Uram , Sarah Wolf , Nataša Djurdjevac Conrad , Martin Weiser

In this paper we propose a novel SEIR stochastic epidemic model. A distinguishing feature of this new model is that it allows us to consider a set up under general latency and infectious period distributions. To some extent, queuing systems…

Quantitative Methods · Quantitative Biology 2023-06-29 Edilson F. Arruda , Rodrigo e Alvim Alexandre , Marcelo D. Fragoso , João B. R. do val , Sinnu S. Thomas

We present a stochastic epidemic model to study the effect of various preventive measures, such as uniform reduction of contacts and transmission, vaccination, isolation, screening and contact tracing, on a disease outbreak in a…

Populations and Evolution · Quantitative Biology 2022-07-08 Martina Favero , Gianpaolo Scalia Tomba , Tom Britton

Testing is a crucial control mechanism in the beginning phase of an epidemic when the vaccines are not yet available. It enables the public health authority to detect and isolate the infected cases from the population, thereby limiting the…

We consider a financial intermediary managing assets and liabilities exposed to several risk sources and seeking an optimal portfolio strategy to minimise the initial capital invested and the total risk associated with investment losses and…

Optimization and Control · Mathematics 2025-05-23 Giorgio Consigli , Darinka Dentcheva , Francesca Maggioni , Giovanni Micheli

The opioid epidemic is a crisis that has plagued the United States (US) for decades. One central issue is inequitable access to treatment for opioid use disorder (OUD), which puts certain populations at a higher risk of opioid overdose. We…

Physics and Society · Physics 2024-03-14 Joyce Luo , Bartolomeo Stellato

Epidemiological models are best suitable to model an epidemic if the spread pattern is stationary. To deal with non-stationary patterns and multiple waves of an epidemic, we develop a hybrid model encompassing epidemic modeling, particle…

Machine Learning · Computer Science 2024-02-01 Naresh Kumar , Seba Susan

Many countries have experienced at least two waves of the COVID-19 pandemic. The second wave is far more dangerous as distinct strains appear more harmful to human health, but it stems from the complacency about the first wave. This paper…

Populations and Evolution · Quantitative Biology 2022-06-29 Edilson F. Arruda , Tarun Sharma , Rodrigo e A. Alexandre , Sinnu Susan Thomas

This paper investigates the dynamics of infectious diseases with a non-exponentially distributed infectious period. This is achieved by considering a multi-stage infection model on networks. Using pairwise approximation with a standard…

Physics and Society · Physics 2015-11-23 N. Sherborne , K. B. Blyuss , I. Z. Kiss

The optimal allocation of vaccines to population subgroups over time is a challenging health care management problem. In the context of a pandemic, the interaction between vaccination policies adopted by multiple agents and the cooperation…

Optimization and Control · Mathematics 2021-09-22 David Rey , Ahmed W Hammad , Meead Saberi

With the emerging COVID-19 crisis, a critical task for public health officials and policy makers is to decide how to prioritize, locate, and allocate scarce resources. To answer these questions, decision makers need to be able to determine…

Inferring how an epidemic will progress and what actions to take when presented with limited information is of critical importance for epidemiologists and health professionals. In real world settings, epidemiology data can be scarce or…

Computation · Statistics 2022-11-02 Georgios Efstathiadis

We study a multi-objective model on the allocation of reusable resources under model uncertainty. Heterogeneous customers arrive sequentially according to a latent stochastic process, request for certain amounts of resources, and occupy…

Optimization and Control · Mathematics 2023-08-02 Xilin Zhang , Wang Chi Cheung

We study the diffusion of epidemics on networks that are partitioned into local communities. The gross structure of hierarchical networks of this kind can be described by a quotient graph. The rationale of this approach is that individuals…

Social and Information Networks · Computer Science 2016-01-19 Stefano Bonaccorsi , Stefania Ottaviano , Delio Mugnolo , Francesco De Pellegrini

Incorporating Renewable Energy Sources (RES) incurs a high level of uncertainties to electric power systems. This level of uncertainties makes the conventional energy management methods inefficient and jeopardizes the security of…

Optimization and Control · Mathematics 2019-10-17 Mohammad Rasoul Narimani , Ali Azizivahed , Ehsan Naderi

When analysing new emerging infectious disease outbreaks one typically has observational data over a limited period of time and several parameters to estimate, such as growth rate, R0, serial or generation interval distribution, latent and…

Applications · Statistics 2018-03-06 Tom Britton , Gianpaolo Scalia Tomba

The frequency of wildfire disasters has surged five-fold in the past 50 years due to climate change. Preemptive de-energization is a potent strategy to mitigate wildfire risks but substantially impacts customers. We propose a multistage…

Optimization and Control · Mathematics 2024-04-10 Hanbin Yang , Noah Rhodes , Haoxiang Yang , Line Roald , Lewis Ntaimo

Containing the recent West African outbreak of Ebola virus (EBOV) required the deployment of substantial global resources. Operationally, health workers and surveillance teams treated cases, collected genetic samples, and tracked case…

Populations and Evolution · Quantitative Biology 2017-12-13 Kyle B. Gustafson , Joshua L. Proctor

We develop a stochastic epidemic model progressing over dynamic networks, where infection rates are heterogeneous and may vary with individual-level covariates. The joint dynamics are modeled as a continuous-time Markov chain such that…

Methodology · Statistics 2021-12-16 Fan Bu , Allison E. Aiello , Alexander Volfovsky , Jason Xu

Spatial spread of infectious diseases among populations via the mobility of humans is highly stochastic and heterogeneous. Accurate forecast/mining of the spread process is often hard to be achieved by using statistical or mechanical…

Social and Information Networks · Computer Science 2016-11-18 Jian-Bo Wang , Lin Wang , Xiang Li
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