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Genomics has revolutionized biology, enabling the interrogation of whole transcriptomes, genome-wide binding sites for proteins, and many other molecular processes. However, individual genomic assays measure elements that interact in vivo…

Machine Learning · Statistics 2022-06-08 Sumanta Basu , Karl Kumbier , James B. Brown , Bin Yu

Feature and Interaction Importance (FII) methods are essential in supervised learning for assessing the relevance of input variables and their interactions in complex prediction models. In many domains, such as personalized medicine, local…

Machine Learning · Statistics 2025-12-15 Kata Vuk , Nicolas Alexander Ihlo , Merle Behr

Random Forest (RF) is an ensemble classification technique that was developed by Breiman over a decade ago. Compared with other ensemble techniques, it has proved its accuracy and superiority. Many researchers, however, believe that there…

Machine Learning · Computer Science 2015-03-19 Khaled Fawagreh , Mohamad Medhat Gaber , Eyad Elyan

Random forest (RF) is one of the most popular methods for estimating regression functions. The local nature of the RF algorithm, based on intra-node means and variances, is ideal when errors are i.i.d. For dependent error processes like…

Machine Learning · Statistics 2021-06-29 Arkajyoti Saha , Sumanta Basu , Abhirup Datta

A compositional tree refers to a tree structure on a set of random variables where each random variable is a node and composition occurs at each non-leaf node of the tree. As a generalization of compositional data, compositional trees…

Methodology · Statistics 2021-04-20 Bingkai Wang , Brian S. Caffo , Xi Luo , Chin-Fu Liu , Andreia V. Faria , Michael I. Miller , Yi Zhao

In materials science, data-driven methods accelerate material discovery and optimization while reducing costs and improving success rates. Symbolic regression is a key to extracting material descriptors from large datasets, in particular…

Machine Learning · Computer Science 2024-10-01 Xiaolin Jiang , Guanqi Liu , Jiaying Xie , Zhenpeng Hu

Random forest (RF) stands out as a highly favored machine learning approach for classification problems. The effectiveness of RF hinges on two key factors: the accuracy of individual trees and the diversity among them. In this study, we…

Machine Learning · Computer Science 2024-10-28 Ye-eun Kim , Seoung Yun Kim , Hyunjoong Kim

Spatial epidemiology identifies the drivers of elevated population-level disease risks, using disease counts, exposures and known confounders at the areal unit level. Poisson regression models are typically used for inference, which…

Methodology · Statistics 2026-02-03 Duncan Lee , Vinny Davies

Taking into account high-order interactions among covariates is valuable in many practical regression problems. This is, however, computationally challenging task because the number of high-order interaction features to be considered would…

Machine Learning · Statistics 2015-06-29 Kazuya Nakagawa , Shinya Suzumura , Masayuki Karasuyama , Koji Tsuda , Ichiro Takeuchi

Random Forests [Breiman:2001] (RF) are a fully non-parametric statistical method requiring no distributional assumptions on covariate relation to the response. RF are a robust, nonlinear technique that optimizes predictive accuracy by…

Computation · Statistics 2016-12-30 John Ehrlinger

We introduce a novel interpretable tree based algorithm for prediction in a regression setting. Our motivation is to estimate the unknown regression function from a functional decomposition perspective in which the functional components…

Machine Learning · Statistics 2023-08-04 Munir Hiabu , Enno Mammen , Joseph T. Meyer

Sampling-based motion planners perform exceptionally well in robotic applications that operate in high-dimensional space. However, most works often constrain the planning workspace rooted at some fixed locations, do not adaptively reason on…

Robotics · Computer Science 2021-03-09 Tin Lai

Objective: Social-environmental data obtained from the U.S. Census is an important resource for understanding health disparities, but rarely is the full dataset utilized for analysis. A barrier to incorporating the full data is a lack of…

Applications · Statistics 2020-09-02 Elizabeth Handorf , Yinuo Yin , Michael Slifker , Shannon Lynch

Decision trees are widely used for their low computational cost, good predictive performance, and ability to assess the importance of features. Though often used in practice for feature selection, the theoretical guarantees of these methods…

Machine Learning · Statistics 2023-03-09 Kiarash Banihashem , MohammadTaghi Hajiaghayi , Max Springer

Random forests are a powerful method for non-parametric regression, but are limited in their ability to fit smooth signals, and can show poor predictive performance in the presence of strong, smooth effects. Taking the perspective of random…

Machine Learning · Statistics 2020-09-08 Rina Friedberg , Julie Tibshirani , Susan Athey , Stefan Wager

Finding statistically significant high-order interaction features in predictive modeling is important but challenging task. The difficulty lies in the fact that, for a recent applications with high-dimensional covariates, the number of…

Machine Learning · Statistics 2015-06-29 S. Suzumura , K. Nakagawa , K. Tsuda , I. Takeuchi

Random forests are widely used in regression. However, the decision trees used as base learners are poor approximators of linear relationships. To address this limitation we propose RaFFLE (Random Forest Featuring Linear Extensions), a…

Machine Learning · Computer Science 2025-02-17 Jakob Raymaekers , Peter J. Rousseeuw , Thomas Servotte , Tim Verdonck , Ruicong Yao

The Distributional Random Forest (DRF) is a recently introduced Random Forest algorithm to estimate multivariate conditional distributions. Due to its general estimation procedure, it can be employed to estimate a wide range of targets such…

Statistics Theory · Mathematics 2023-12-20 Jeffrey Näf , Corinne Emmenegger , Peter Bühlmann , Nicolai Meinshausen

Precision medicine is becoming a focus in medical research recently, as its implementation brings values to all stakeholders in the healthcare system. Various statistical methodologies have been developed tackling problems in different…

Quantitative Methods · Quantitative Biology 2019-10-07 Zhen Zeng , Yuefeng Lu , Judong Shen , Wei Zheng , Peter Shaw , Mary Beth Dorr

Random forest (Leo Breiman 2001a) (RF) is a non-parametric statistical method requiring no distributional assumptions on covariate relation to the response. RF is a robust, nonlinear technique that optimizes predictive accuracy by fitting…

Computation · Statistics 2016-12-30 John Ehrlinger
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