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Neural network models in neuroscience allow one to study how the connections between neurons shape the activity of neural circuits in the brain. In this chapter, we study Combinatorial Threshold-Linear Networks (CTLNs) in order to…

Neurons and Cognition · Quantitative Biology 2018-04-05 Katherine Morrison , Carina Curto

Threshold-linear networks (TLNs) are models of neural networks that consist of simple, perceptron-like neurons and exhibit nonlinear dynamics that are determined by the network's connectivity. The fixed points of a TLN, including both…

Neurons and Cognition · Quantitative Biology 2018-08-06 Carina Curto , Jesse Geneson , Katherine Morrison

Combinatorial threshold-linear networks (CTLNs) are a special class of recurrent neural networks whose dynamics are tightly controlled by an underlying directed graph. Recurrent networks have long been used as models for associative memory…

Neurons and Cognition · Quantitative Biology 2023-11-21 Carina Curto , Jesse Geneson , Katherine Morrison

Combinatorial threshold-linear networks (CTLNs) are a special class of inhibition-dominated TLNs defined from directed graphs. Like more general TLNs, they display a wide variety of nonlinear dynamics including multistability, limit cycles,…

Neurons and Cognition · Quantitative Biology 2022-08-16 Caitlyn Parmelee , Samantha Moore , Katherine Morrison , Carina Curto

Graphical domination was first introduced in [1] in the context of combinatorial threshold-linear networks (CTLNs). There it was shown that when a domination relationship exists between a pair of vertices in a graph, certain fixed points in…

Neurons and Cognition · Quantitative Biology 2025-10-07 Carina Curto

The architecture of a neural network constrains the potential dynamics that can emerge. Some architectures may only allow for a single dynamic regime, while others display a great deal of flexibility with qualitatively different dynamics…

Combinatorics · Mathematics 2020-08-04 Carina Curto , Christopher Langdon , Katherine Morrison

To any inhibition-dominated threshold-linear network (TLN) we can associate a directed graph that captures the pattern of strong and weak inhibition between neurons. Robust motifs are graphs for which the structure of fixed points in the…

Neurons and Cognition · Quantitative Biology 2019-12-18 Carina Curto , Christopher Langdon , Katherine Morrison

The irreducible complexity of natural phenomena has led Graph Neural Networks to be employed as a standard model to perform representation learning tasks on graph-structured data. While their capacity to capture local and global patterns is…

Machine Learning · Computer Science 2024-02-13 Lorenzo Giusti

Sequences of neural activity arise in many brain areas, including cortex, hippocampus, and central pattern generator circuits that underlie rhythmic behaviors like locomotion. While network architectures supporting sequence generation vary…

Neurons and Cognition · Quantitative Biology 2022-08-16 Caitlyn Parmelee , Juliana Londono Alvarez , Carina Curto , Katherine Morrison

Graph neural networks (GNNs) provide state-of-the-art results in a wide variety of tasks which typically involve predicting features at the vertices of a graph. They are built from layers of graph convolutions which serve as a powerful…

Machine Learning · Statistics 2024-11-08 Mauricio Velasco , Kaiying O'Hare , Bernardo Rychtenberg , Soledad Villar

Deep Neural Networks are, from a physical perspective, graphs whose `links` and `vertices` iteratively process data and solve tasks sub-optimally. We use Complex Network Theory (CNT) to represents Deep Neural Networks (DNNs) as directed…

Machine Learning · Computer Science 2022-09-14 Emanuele La Malfa , Gabriele La Malfa , Claudio Caprioli , Giuseppe Nicosia , Vito Latora

This dissertation explores applications of discrete geometry in mathematical neuroscience. We begin with convex neural codes, which model the activity of hippocampal place cells and other neurons with convex receptive fields. In Chapter 4,…

Neurons and Cognition · Quantitative Biology 2022-09-19 Caitlin Lienkaemper

We study a generic family of nonlinear dynamics on undirected networks generalising linear consensus. We find a compact expression for its equilibrium points in terms of the topology of the network and classify their stability using the…

Dynamical Systems · Mathematics 2021-12-07 Marc Homs-Dones , Karel Devriendt , Renaud Lambiotte

Neuronal networks constitute a special class of dynamical systems, as they are formed by individual geometrical components, namely the neurons. In the existing literature, relatively little attention has been given to the influence of…

Neurons and Cognition · Quantitative Biology 2015-05-13 Sebastian Ahnert , Luciano da Fontoura Costa

Neural networks are often represented as graphs of connections between neurons. However, despite their wide use, there is currently little understanding of the relationship between the graph structure of the neural network and its…

Machine Learning · Computer Science 2020-08-28 Jiaxuan You , Jure Leskovec , Kaiming He , Saining Xie

The nerve theorem is a basic result of algebraic topology that plays a central role in computational and applied aspects of the subject. In topological data analysis, one often needs a nerve theorem that is functorial in an appropriate…

Algebraic Topology · Mathematics 2025-06-04 Ulrich Bauer , Michael Kerber , Fabian Roll , Alexander Rolle

In this paper, we interpret Deep Neural Networks with Complex Network Theory. Complex Network Theory (CNT) represents Deep Neural Networks (DNNs) as directed weighted graphs to study them as dynamical systems. We efficiently adapt CNT…

Machine Learning · Computer Science 2021-10-19 Emanuele La Malfa , Gabriele La Malfa , Giuseppe Nicosia , Vito Latora

Deep Neural Networks (DNNs) can be represented as graphs whose links and vertices iteratively process data and solve tasks sub-optimally. Complex Network Theory (CNT), merging statistical physics with graph theory, provides a method for…

Machine Learning · Computer Science 2024-04-19 Emanuele La Malfa , Gabriele La Malfa , Giuseppe Nicosia , Vito Latora

Threshold-linear networks are a common class of firing rate models that describe recurrent interactions among neurons. Unlike their linear counterparts, these networks generically possess multiple stable fixed points (steady states), making…

Neurons and Cognition · Quantitative Biology 2016-12-28 Carina Curto , Katherine Morrison

Networks of interconnected neurons display diverse patterns of collective activity. Relating this collective activity to the network's connectivity structure is a key goal of computational neuroscience. We approach this question for…

Neurons and Cognition · Quantitative Biology 2025-06-09 Caitlin Lienkaemper , Gabriel Koch Ocker
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