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We develop a framework for comparing data manifolds, aimed, in particular, towards the evaluation of deep generative models. We describe a novel tool, Cross-Barcode(P,Q), that, given a pair of distributions in a high-dimensional space,…

Supervised learning in function spaces is an emerging area of machine learning research with applications to the prediction of complex physical systems such as fluid flows, solid mechanics, and climate modeling. By directly learning maps…

Machine Learning · Computer Science 2022-06-09 Jacob H. Seidman , Georgios Kissas , Paris Perdikaris , George J. Pappas

Recent analysis identified distinct genomic subtypes of lower-grade glioma tumors which are associated with shape features. In this study, we propose a fully automatic way to quantify tumor imaging characteristics using deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2019-06-11 Mateusz Buda , Ashirbani Saha , Maciej A Mazurowski

Accurate extraction of molecular representations is a critical step in the drug discovery process. In recent years, significant progress has been made in molecular representation learning methods, among which multi-modal molecular…

Machine Learning · Computer Science 2025-05-13 Rong Yin , Ruyue Liu , Xiaoshuai Hao , Xingrui Zhou , Yong Liu , Can Ma , Weiping Wang

Nonlinear manifold learning from unorganized data points is a very challenging unsupervised learning and data visualization problem with a great variety of applications. In this paper we present a new algorithm for manifold learning and…

Machine Learning · Computer Science 2016-08-31 Zhenyue Zhang , Hongyuan Zha

Diffusion magnetic resonance imaging (dMRI) is a crucial non-invasive technique for exploring the microstructure of the living human brain. Traditional hand-crafted and model-based tissue microstructure reconstruction methods often require…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Xinrui Ma , Jian Cheng , Wenxin Fan , Ruoyou Wu , Yongquan Ye , Shanshan Wang

We propose a fine-tuning algorithm for brain tumor segmentation that needs only a few data samples and helps networks not to forget the original tasks. Our approach is based on active learning and meta-learning. One of the difficulties in…

Image and Video Processing · Electrical Eng. & Systems 2023-05-17 Seungyub Han , Yeongmo Kim , Seokhyeon Ha , Jungwoo Lee , Seunghong Choi

Recently, deep learning has been adopted to the glaucoma classification task with performance comparable to that of human experts. However, a well trained deep learning model demands a large quantity of properly labeled data, which is…

Computer Vision and Pattern Recognition · Computer Science 2020-07-23 Junde Wu , Shuang Yu , Wenting Chen , Kai Ma , Rao Fu , Hanruo Liu , Xiaoguang Di , Yefeng Zheng

Masking strategies commonly employed in natural language processing are still underexplored in vision tasks such as concept learning, where conventional methods typically rely on full images. However, using masked images diversifies…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Yuwei Sun , Lu Mi , Ippei Fujisawa , Ruiqiao Mei , Jimin Chen , Siyu Zhu , Ryota Kanai

The combination of tomographic imaging and deep learning, or machine learning in general, promises to empower not only image analysis but also image reconstruction. The latter aspect is considered in this perspective article with an…

Quantitative Methods · Quantitative Biology 2016-11-07 Ge Wang

Topological data analysis (TDA) is a branch of computational mathematics, bridging algebraic topology and data science, that provides compact, noise-robust representations of complex structures. Deep neural networks (DNNs) learn millions of…

We explore two differentiable deep declarative layers, namely least squares on sphere (LESS) and implicit eigen decomposition (IED), for learning the principal matrix features (PMaF). It can be used to represent data features with a…

Machine Learning · Computer Science 2023-07-04 Zhiwei Xu , Hao Wang , Yanbin Liu , Stephen Gould

Multiview self-supervised representation learning roots in exploring semantic consistency across data of complex intra-class variation. Such variation is not directly accessible and therefore simulated by data augmentations. However,…

Computer Vision and Pattern Recognition · Computer Science 2022-11-08 Yu Yang , Wing Yin Cheung , Chang Liu , Xiangyang Ji

Skin cancer is by far in top-3 of the world's most common cancer. Among different skin cancer types, melanoma is particularly dangerous because of its ability to metastasize. Early detection is the key to success in skin cancer treatment.…

Artificial Intelligence · Computer Science 2020-09-15 Duyen N. T. Le , Hieu X. Le , Lua T. Ngo , Hoan T. Ngo

Object recognition is a key enabler across industry and defense. As technology changes, algorithms must keep pace with new requirements and data. New modalities and higher resolution sensors should allow for increased algorithm robustness.…

Computer Vision and Pattern Recognition · Computer Science 2020-12-24 Samuel Rivera , Joel Klipfel , Deborah Weeks

Applying deep learning methods to mammography assessment has remained a challenging topic. Dense noise with sparse expressions, mega-pixel raw data resolution, lack of diverse examples have all been factors affecting performance. The lack…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Ulzee An , Khader Shameer , Lakshmi Subramanian

The examination of histopathology images is considered to be the gold standard for the diagnosis and stratification of cancer patients. A key challenge in the analysis of such images is their size, which can run into the gigapixels and can…

Image and Video Processing · Electrical Eng. & Systems 2021-09-09 Joseph Boyd , Mykola Liashuha , Eric Deutsch , Nikos Paragios , Stergios Christodoulidis , Maria Vakalopoulou

Since higher-order tensors are naturally suitable for representing multi-dimensional data in real-world, e.g., color images and videos, low-rank tensor representation has become one of the emerging areas in machine learning and computer…

Computer Vision and Pattern Recognition · Computer Science 2022-12-02 Yisi Luo , Xile Zhao , Zhemin Li , Michael K. Ng , Deyu Meng

Manifold learning (ML), known also as non-linear dimension reduction, is a set of methods to find the low dimensional structure of data. Dimension reduction for large, high dimensional data is not merely a way to reduce the data; the new…

Machine Learning · Statistics 2023-11-08 Marina Meilă , Hanyu Zhang

Classical unsupervised learning methods like clustering and linear dimensionality reduction parametrize large-scale geometry when it is discrete or linear, while more modern methods from manifold learning find low dimensional representation…

Machine Learning · Computer Science 2025-09-23 Luis Scoccola , Uzu Lim , Heather A. Harrington
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