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When controlling an emerging outbreak of an infectious disease it is essential to know the key epidemiological parameters, such as the basic reproduction number $R_0$ and the control effort required to prevent a large outbreak. These…

Populations and Evolution · Quantitative Biology 2016-04-18 Pieter Trapman , Frank Ball , Jean-Stéphane Dhersin , Viet Chi Tran , Jacco Wallinga , Tom Britton

The interplay of biological, social, structural and random factors makes disease forecasting extraordinarily complex. The course of an epidemic exhibits average growth dynamics determined by features of the pathogen and the population, yet…

Populations and Evolution · Quantitative Biology 2022-02-24 Andrea J. Allen , Mariah C. Boudreau , Nicholas J. Roberts , Antoine Allard , Laurent Hébert-Dufresne

The emergence or adaptation of pathogens may lead to epidemics, highlighting the need for a thorough understanding of pathogen evolution. The tradeoff hypothesis suggests that virulence evolves to reach an optimal transmission intensity…

Populations and Evolution · Quantitative Biology 2024-12-09 Daniel A. M. Villela

Epidemic models study the spread of an undesired agent through a population, be it infectious diseases through a country, misinformation in online social media, or pests infesting a region. In combating these epidemics, we rely neither on…

It is a fundamental question in disease modelling how the initial seeding of an epidemic, spreading over a network, determines its final outcome. Research in this topic has primarily concentrated on finding the seed configuration which…

Physics and Society · Physics 2021-11-16 Gergely Ódor , Domonkos Czifra , Júlia Komjáthy , László Lovász , Márton Karsai

A key parameter in models for the spread of infectious diseases is the basic reproduction number $R_0$, which is the expected number of secondary cases a typical infected primary case infects during its infectious period in a large mostly…

Populations and Evolution · Quantitative Biology 2017-09-05 Kristoffer Spricer , Pieter Trapman

A current challenge for disease modeling and public health is understanding pathogen dynamics across scales since their ecology and evolution ultimately operate on several coupled scales. This is particularly true for vector-borne diseases,…

Populations and Evolution · Quantitative Biology 2019-12-19 Hayriye Gulbudak

Changes in human behavior are increasingly recognized as a major determinant of epidemic dynamics. Although collective activity can be modified through imposed measures to control epidemic progression, spontaneous changes can also arise as…

Populations and Evolution · Quantitative Biology 2021-05-25 Susanna Manrubia , Damián H. Zanette

Risk-driven behavior provides a feedback mechanism through which individuals both shape and are collectively affected by an epidemic. We introduce a general and flexible compartmental model to study the effect of heterogeneity in the…

Random walk is one of the basic mechanisms found in many network applications. We study the epidemic spreading dynamics driven by biased random walks on complex networks. In our epidemic model, each time infected nodes constantly spread…

Physics and Society · Physics 2015-06-22 Cunlai Pu , Siyuan Li , Jian Yang

In numerous contexts, individuals may decide whether they take actions to mitigate the spread of disease, or not. Mitigating the spread of disease requires an individual to change their routine behaviours to benefit others, resulting in a…

Physics and Society · Physics 2020-08-11 Julie Rowlett , Carl-Joar Karlsson

Two factors that are often ignored but could play a crucial role in the progression of an infectious disease are the distributions of inherent susceptibility ($\sigma_{inh}$) and external infectivity ($\iota_{ext}$), in a given population.…

Populations and Evolution · Quantitative Biology 2021-01-01 Saumyak Mukherjee , Sayantan Mondal , Biman Bagchi

Human diseases spread over networks of contacts between individuals and a substantial body of recent research has focused on the dynamics of the spreading process. Here we examine a model of two competing diseases spreading over the same…

Physics and Society · Physics 2015-03-19 Brian Karrer , M. E. J. Newman

We consider the class of SIS epidemic models in which a large population of individuals chooses whether to adopt protection or to remain unprotected as the epidemic evolves. For a susceptible individual, adopting protection reduces the…

Systems and Control · Electrical Eng. & Systems 2022-03-22 Abhisek Satapathi , Narendra Kumar Dhar , Ashish R. Hota , Vaibhav Srivastava

In this paper, we study the interplay between individual behaviors and epidemic spreading in a dynamical network. We distribute agents on a square-shaped region with periodic boundary conditions. Every agent is regarded as a node of the…

Physics and Society · Physics 2018-02-14 Han-Xin Yang , Ming Tang , Zhen Wang

Epidemiological dynamics are affected by the spatial and demographic structure of the host population. Households and neighbourhoods are known to be important groupings but little is known about the epidemiological interplay between them.…

Populations and Evolution · Quantitative Biology 2024-12-12 Abby Barlow , Ben Adams , Sarah Penington

Infectious diseases outbreaks are often characterized by a spatial component induced by hosts' distribution, mobility, and interactions. Spatial models that incorporate hosts' movements are being used to describe these processes, to…

Physics and Society · Physics 2012-07-20 Chiara Poletto , Michele Tizzoni , Vittoria Colizza

During infectious disease epidemics, pathogen transmission occurs in host populations made up of interacting subpopulations. Using stochastic simulation and analytical approximations, we examine how outbreak sizes in networked populations…

Populations and Evolution · Quantitative Biology 2026-01-21 Makoto Ueki , Robin N. Thompson , Murad Banaji

Susceptibility governs the dynamics of contagion. The classical SIR model is one of the simplest compartmental models of contagion spread, assuming a single shared susceptibility level. However, variation in susceptibility over a population…

Populations and Evolution · Quantitative Biology 2020-09-22 Christopher Rose , Andrew J. Medford , C. Franklin Goldsmith , Tejs Vegge , Joshua Weitz , Andrew A. Peterson

Several systems can be modeled as sets of interdependent networks where each network contains distinct nodes. Diffusion processes like the spreading of a disease or the propagation of information constitute fundamental phenomena occurring…

Social and Information Networks · Computer Science 2015-06-23 Mostafa Salehi , Payam Siyari , Matteo Magnani , Danilo Montesi