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The movement of molecules inside living cells is a fundamental feature of biological processes. The ability to both observe and analyse the details of molecular diffusion in vivo at the single molecule and single cell level can add…

Quantitative Methods · Quantitative Biology 2012-11-21 Alex Robson , Kevin Burrage , Mark Leake

Investigating the cellular internalization pathways of single molecules or single nano-objects is important to understanding cell-matter interactions and to applications in drug delivery and discovery. Imaging and tracking the motion of…

Biological Physics · Physics 2015-06-04 Guosong Hong , Justin Z. Wu , Joshua T. Robinson , Hailiang Wang , Bo Zhang , Hongjie Dai

The Feynman path integral approach for solving the motion of a droplet along a silicon oil surface is developed by replacing the Planck constant by a surrogate parameter. The latter is proportional to the surface tension of the silicon oil…

Fluid Dynamics · Physics 2013-10-21 Valeriy I. Sbitnev

In this article we present an analytic solution of the famous problem of diffraction and interference of electrons through one and two slits (for simplicity, only the one-dimensional case is considered). In addition to exact formulas, we…

Quantum Physics · Physics 2015-10-30 Mathieu Beau

The use of ultra-thin, i.e., monolayer films plays an important role for the emerging field of nano-fluidics. Since the dynamics of such films is governed by the interplay between substrate-fluid and fluid-fluid interactions, the transport…

Other Condensed Matter · Physics 2009-11-11 M. N. Popescu , S. Dietrich , G. Oshanin

Electrokinetic transport phenomena can strongly influence the behaviour of macromolecules and colloidal particles in solution, with applications in, e.g., DNA translocation through nanopores, electro-osmotic flow in nanocapillaries, and…

Soft Condensed Matter · Physics 2016-08-03 Georg Rempfer , Gary B. Davies , Christian Holm , Joost de Graaf

Self-driven nanofluidic flow at the liquid-air interface is a non-intuitive phenomenon. This flow behaviour was not driven by classical pressure difference or evaporation only. Depending on the position of the nanofluidic pore we can…

Quantum Physics · Physics 2022-09-02 Vinitha Johny , Sonia Contera , Siddharth Ghosh

We introduce a theoretical and numerical method to investigate the flow of charged fluid mixtures under extreme confinement. We model the electrolyte solution as a ternary mixture, comprising two ionic species of opposite charge and a third…

Mesoscale and Nanoscale Physics · Physics 2012-09-13 Umberto Marini Bettolo Marconi , Simone Melchionna

Plasmonic waveguides offer the unique possibility to confine light far below the diffraction limit. Past room temperature experiments of single quantum emitters coupled to such waveguides have mainly focused on efficient channelling of the…

Optics · Physics 2020-03-02 Christian Schörner , Markus Lippitz

For distinguishable particles it is well known that Brownian motion and a Feynman-Kac functional can be used to calculate the path integral (for imaginary times) for a general class of scalar potentials. In order to treat identical…

Condensed Matter · Physics 2009-10-28 L. F. Lemmens , F. Brosens , J. T. Devreese

Achieving dynamic manipulation and control of single molecules at high spatio-temporal resolution is pivotal for advancing atomic-scale computing and nanorobotics. However, this endeavour is critically challenged by complex nature of atomic…

Atomic and Molecular Clusters · Physics 2024-06-18 Divyam Neer Verma , KV Chinmaya , Jan Heck , G Mohan Rao , Sonia Contera , Moumita Ghosh , Siddharth Ghosh

Plastic nanoparticles present technological opportunities and environmental concerns, but measurement challenges impede product development and hazard assessment. To meet these challenges, we advance a lateral nanoflow assay that integrates…

Soft Condensed Matter · Physics 2022-05-19 Kuo-Tang Liao , Andrew C. Madison , Adam L. Pintar , B. Robert Ilic , Craig R. Copeland , Samuel M. Stavis

The path-integral representation of Smoluchowski equation is exploited to explore the stochastic dynamics of a tagged Brownian particle within an interacting system where hydrodynamic effects are neglected. In particular, this formalism is…

Single-molecule fluorescence spectroscopy is a powerful method that avoids ensemble averaging, but its temporal resolution is limited by the fluorescence lifetime to nanoseconds at most. At the ensemble level, two-dimensional spectroscopy…

Optics · Physics 2024-10-11 Sanchayeeta Jana , Simon Durst , Markus Lippitz

Porous materials are used in a variety of industrial applications owing to their large surface areas, large pore volumes, hierarchical porosities, and low densities. The motion of particles inside the pores of porous materials has attracted…

Chemical Physics · Physics 2023-11-21 Yusaku Abe , Naoki Tomioka , Yu Matsuda

In this work, a new algorithm is proposed to compute single particle (infinite dilution) thermodiffusion using Non-Equilibrium Molecular Dynamics simulations through the estimation of the thermophoretic force that applies on a solute…

Statistical Mechanics · Physics 2009-11-13 Guillaume Galliéro , S. Volz

Despite mass flow is arguably the most elementary transport associated to nanofluidics, its measurement still constitutes a significant bottleneck for the development of this promising field. Here, we investigate how a liquid flow perturbs…

Soft Condensed Matter · Physics 2020-01-29 Simon Gravelle , Christophe Ybert

Single-molecule detection at a nanometric interface in a femtomolar solution, can take weeks as the encounter rate between the diffusing molecule to be detected and the transducing nano-device is negligibly small. On the other hand, several…

A highly sensitive optical capillary electrophoresis measurement method based on a nanofluidic optical fiber platform is presented. By using scaling arguments and considering realistic instrument limitations, I underline the feasibility of…

Soft Condensed Matter · Physics 2016-01-07 Sanli Faez

Single particle-resolved fluorescence imaging is an enabling technology in cold-atom physics. However, so far, this technique was not available for nanophotonic atom-light interfaces. Here, we image single atoms that are trapped and…

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