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We propose FiberNet, a method to estimate \emph{in-vivo} the cardiac fiber architecture of the human atria from multiple catheter recordings of the electrical activation. Cardiac fibers play a central role in the electro-mechanical function…

Image and Video Processing · Electrical Eng. & Systems 2022-07-25 Carlos Ruiz Herrera , Thomas Grandits , Gernot Plank , Paris Perdikaris , Francisco Sahli Costabal , Simone Pezzuto

The anisotropic structure of the myocardium is a key determinant of the cardiac function. To date, there is no imaging modality to assess in-vivo the cardiac fiber structure. We recently proposed Fibernet, a method for the automatic…

Machine Learning · Computer Science 2024-11-01 Efraín Magaña , Simone Pezzuto , Francisco Sahli Costabal

Electroanatomical mapping, a keystone diagnostic tool in cardiac electrophysiology studies, can provide high-density maps of the local electric properties of the tissue. It is therefore tempting to use such data to better individualize…

Optimization and Control · Mathematics 2021-02-03 Thomas Grandits , Simone Pezzuto , Jolijn M. Lubrecht , Thomas Pock , Gernot Plank , Rolf Krause

Knowledge of appropriate local fiber architecture is necessary to simulate patient-specific electromechanics in the human heart. However, it is not yet possible to reliably measure in-vivo fiber directions, especially in human atria. Thus,…

The analysis of electrical impulse phenomena in cardiac muscle tissue is important for the diagnosis of heart rhythm disorders and other cardiac pathophysiology. Cardiac mapping techniques acquire local temporal measurements and combine…

Medical Physics · Physics 2022-03-21 Jan Lebert , Namita Ravi , Flavio Fenton , Jan Christoph

Atrial Fibrillation (AF) is characterized by disorganised electrical activity in the atria and is known to be sustained by the presence of regions of fibrosis (scars) or functional cellular remodeling, both of which may lead to areas of…

Non-invasive assessment of the electrical activation pattern can significantly contribute to the diagnosis and treatment of cardiac arrhythmias, due to faster and safer diagnosis, improved surgical planning and easier follow-up. One…

Medical Physics · Physics 2024-01-09 Nathan Dermul , Hans Dierckx

Accurate forward modelling is essential for non-invasive cardiac electrophysiology, particularly in atrial fibrillation, where electrical activation is highly disorganised. Conventional physics-based forward models require explicit…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Shaheim Ogbomo-Harmitt , Cesare Magnetti , Jakub Grzelak , Oleg Aslanidi

The contractile motion of the heart is strongly determined by the distribution of the fibers that constitute cardiac tissue. Strain analysis informed with the orientation of fibers allows to describe several pathologies that are typically…

Image and Video Processing · Electrical Eng. & Systems 2025-09-12 Felipe Álvarez Barrientos , Tomás Banduc , Isabeau Sirven , Francisco Sahli Costabal

One of the challenges in the development of patient-specific models of cardiac arrhythmias for clinical applications has been accounting for myocardial fiber organization. The fiber varies significantly from heart to heart, but cannot be…

Medical Physics · Physics 2023-07-22 Jiyue He , Arkady Pertsov , John Bullinga , Rahul Mangharam

Cardiac arrhythmogenesis is governed by complex electromechanical interactions that are not directly observable in vivo, motivating the development of non-invasive computational approaches for reconstructing three-dimensional activation…

Medical Physics · Physics 2026-03-05 Nathan Dermul , Hans Dierckx

Atrial Fibrillation (AF) is a heart's arrhythmia which, despite being often asymptomatic, represents an important risk factor for stroke, therefore being able to predict AF at the electrocardiogram exam, would be of great impact on actively…

Signal Processing · Electrical Eng. & Systems 2022-02-14 A. Scagnetto , G. Barbati , I. Gandin , C. Cappelletto , G. Baj , A. Cazzaniga , F. Cuturello , A. Ansuini , L. Bortolussi , A. Di Lenarda

Left atrial voltage maps are routinely acquired during electroanatomic mapping in patients undergoing catheter ablation for atrial fibrillation. For patients, who have prior catheter ablation when they are in sinus rhythm, the voltage map…

Medical Physics · Physics 2022-11-10 Jiyue He , Kuk Jin Jang , Katie Walsh , Jackson Liang , Sanjay Dixit , Rahul Mangharam

Cardiovascular waveforms contain information for clinical diagnosis. By "learning" and organizing the subtle change of waveform morphology from large amounts of raw waveform data, unsupervised manifold learning helps delineate a…

Quantitative Methods · Quantitative Biology 2019-12-03 Shen-Chih Wang , Hau-Tieng Wu , Po-Hsun Huang , Cheng-Hsi Chang , Chien-Kun Ting , Yu-Ting Lin

The heartbeat is mediated between cardiac cells by waves of electrical depolarisation. During cardiac arrhythmias, electrical activity was found to be organised in scroll waves which rotate around a dynamical filament curve. In this thesis,…

Biological Physics · Physics 2015-11-13 Hans J. F. M. Dierckx

The complexity of the patterns associated with Atrial Fibrillation (AF) and the high level of noise affecting these patterns have significantly limited the current signal processing and shallow machine learning approaches to get accurate AF…

Quantitative Methods · Quantitative Biology 2019-02-18 Sajad Mousavi , Fatemeh Afghah , Abolfazl Razi , U. Rajendra Acharya

Rule-based methods are often used for assigning fiber orientation to cardiac anatomical models. However, existing methods have been developed using data mostly from the left ventricle. As a consequence, fiber information obtained from…

Electroanatomical mapping is a technique used in cardiology to create a detailed 3D map of the electrical activity in the heart. It is useful for diagnosis, treatment planning and real time guidance in cardiac ablation procedures to treat…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Sunil Mathew , Jasbir Sra , Daniel B. Rowe

We present a convolutional-recurrent neural network architecture with long short-term memory for real-time processing and classification of digital sensor data. The network implicitly performs typical signal processing tasks such as…

Active stress models in cardiac biomechanics account for the mechanical deformation caused by muscle activity, thus providing a link between the electrophysiological and mechanical properties of the tissue. The accurate assessment of active…

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