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This study uses a one dimensional fluid dynamics arterial network model to infer changes in hemodynamic quantities associated with pulmonary hypertension in mice. Data for this study include blood flow and pressure measurements from the…

Remote photoplethysmography (rPPG) is an attractive camera-based health monitoring method that can measure the heart rhythm from facial videos. Many well-established deep-learning models have been reported to measure heart rate (HR) and…

Computer Vision and Pattern Recognition · Computer Science 2022-12-22 Jialiang Zhuang , Yuheng Chen , Yun Zhang , Xiujuan Zheng

Detection and monitoring of patients with pulmonary hypertension, defined as mean blood pressure in the main pulmonary artery above 25 mmHg, requires a combination of imaging and hemodynamic measurements. This study demonstrates how to…

Quantitative Methods · Quantitative Biology 2020-02-21 Megan J. Chambers , Mitchel J. Colebank , M Umar Qureshi , Rachel Clipp , Mette S. Olufsen

Image-based computational models of the heart represent a powerful tool to shed new light on the mechanisms underlying physiological and pathological conditions in cardiac function and to improve diagnosis and therapy planning. However, in…

Tissues and Organs · Quantitative Biology 2021-01-15 Laura Marx , Justyna A. Niestrawska , Matthias A. F. Gsell , Federica Caforio , Gernot Plank , Christoph M. Augustin

Cardiovascular hemodynamic fields provide valuable medical decision markers for coronary artery disease. Computational fluid dynamics (CFD) is the gold standard for accurate, non-invasive evaluation of these quantities in silico. In this…

Quantitative Methods · Quantitative Biology 2025-08-27 Julian Suk , Guido Nannini , Patryk Rygiel , Christoph Brune , Gianluca Pontone , Alberto Redaelli , Jelmer M. Wolterink

Machine learning models have the potential to identify cardiovascular diseases (CVDs) early and accurately in primary healthcare settings, which is crucial for delivering timely treatment and management. Although population-based CVD risk…

Morphology of cardiovascular tissue is influenced by the unsteady behavior of the blood flow and vice versa. Therefore, the pathogenesis of several cardiovascular diseases is directly affected by the blood-flow dynamics. Understanding flow…

Blood pressure (BP) monitoring is vital in daily healthcare, especially for cardiovascular diseases. However, BP values are mainly acquired through the contact sensing method, which is inconvenient and unfriendly to continuous BP…

Image and Video Processing · Electrical Eng. & Systems 2022-06-24 Jialiang Zhuang , Bin Li , Yun Zhang , Yuheng Chen , Xiujuan Zheng

Cardiovascular modeling has rapidly advanced over the past few decades due to the rising needs for health tracking and early detection of cardiovascular diseases. While 1-D arterial models offer an attractive compromise between…

Valvular heart diseases are growing concern in impoverished parts of the world, such as Southern-Africa, claiming more than 31 % of total deaths related to cardiovascular diseases. The ability to model the effects of regurgitant and…

Medical Physics · Physics 2022-04-11 Ryno Laubscher , Jacques Liebenberg , Philip Herbst

Intracardiac flow patterns are shaped by the coupled motion of the cardiac chambers and heart valves and provide important information about cardiac function. However, clinical flow imaging remains limited by exam times, noise, resolution,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Fanwei Kong , Aaron Brown , Michael Loecher , Perry S. Choi , Lei Shi , Michael Ma , Daniel B. Ennis , Alison Marsden

Vessel dynamics simulation is vital in studying the relationship between geometry and vascular disease progression. Reliable dynamics simulation relies on high-quality vascular meshes. Most of the existing mesh generation methods highly…

Image and Video Processing · Electrical Eng. & Systems 2024-12-03 Dengqiang Jia , Xinnian Yang , Xiaosong Xiong , Shijie Huang , Feiyu Hou , Li Qin , Kaicong Sun , Kannie Wai Yan Chan , Dinggang Shen

Computational fluid dynamics (CFD) can be used to simulate vascular haemodynamics and analyse potential treatment options. CFD has shown to be beneficial in improving patient outcomes. However, the implementation of CFD for routine clinical…

Computational fluid dynamics (CFD) is increasingly used to study blood flows in patient-specific arteries for understanding certain cardiovascular diseases. The techniques work quite well for relatively simple problems, but need…

Computational Physics · Physics 2018-10-11 Fande Kong , Vitaly Kheyfets , Ender Finol , Xiao-Chuan Cai

Clinical risk stratification for sudden cardiac death (SCD) in hypertrophic cardiomyopathy (HC) employs rules derived from American College of Cardiology Foundation/American Heart Association (ACCF/AHA) guidelines or the HCM Risk-SCD model…

We propose a novel approach to generate samples from the conditional distribution of patient-specific cardiovascular models given a clinically aquired image volume. A convolutional neural network architecture with dropout layers is first…

Quantitative Methods · Quantitative Biology 2021-09-01 Gabriel Maher , Casey Fleeter , Daniele Schiavazzi , Alison Marsden

Stochastic epidemic models, generally more realistic than deterministic counterparts, have often been seen too complex for rigorous mathematical analysis because of level of details it requires to comprehensively capture the dynamics of…

Populations and Evolution · Quantitative Biology 2018-06-13 Xin Liu , Anuj Mubayi , Dominik Reinhold , Liu Zhu

Background and Objective: Diabetes presents a significant challenge to healthcare due to the negative impact of poor blood sugar control on health and associated complications. Computer simulation platforms, notably exemplified by the…

Applications · Statistics 2024-09-10 Mohammadreza Ganji , Anas El Fathi , Chiara Fabris , Dayu Lv , Boris Kovatchev , Marc Breton

Cardiac fluid dynamics fundamentally involves interactions between complex blood flows and the structural deformations of the muscular heart walls and the thin, flexible valve leaflets. There has been longstanding scientific, engineering,…

Hemodynamic quantities are valuable biomedical risk factors for cardiovascular pathology such as atherosclerosis. Non-invasive, in-vivo measurement of these quantities can only be performed using a select number of modalities that are not…

Quantitative Methods · Quantitative Biology 2026-02-23 Julian Suk , Dieuwertje Alblas , Barbara A. Hutten , Albert Wiegman , Christoph Brune , Pim van Ooij , Jelmer M. Wolterink