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For dynamical systems arising from chemical reaction networks, persistence is the property that each species concentration remains positively bounded away from zero, as long as species concentrations were all positive in the beginning. We…

Dynamical Systems · Mathematics 2016-07-29 Michael Marcondes de Freitas , Elisenda Feliu , Carsten Wiuf

We introduce a new topological descriptor of a network called the density decomposition which is a partition of the nodes of a network into regions of uniform density. The decomposition we define is unique in the sense that a given network…

Social and Information Networks · Computer Science 2017-12-18 Glencora Borradaile , Theresa Migler , Gordon Wilfong

Complex balanced mass-action systems (CBMASs) are of great importance in the filed of biochemical reaction networks. However analyzing the persistence of these networks with high dimensions and time delays poses significant challenges. To…

Dynamical Systems · Mathematics 2023-07-21 Xiaoyu Zhang , Chunhou Gao , Denis Dochain

This paper investigates the problem of decomposition with respect to outputs for Boolean control networks (BCNs). First, with the linear expression of BCNs and the matrix semi-tensor product, some algebraic equivalent conditions for the…

Optimization and Control · Mathematics 2014-07-09 Yunlei Zou , Jiandong Zhu

We introduce the notion of corresponding a chemical reaction network to a split network translation, and use this novel process to extend the scope of existing network-based theory for characterizing the steady state set of mass-action…

Dynamical Systems · Mathematics 2021-04-09 Matthew D. Johnston

Reversibility, weak reversibility and deficiency, detailed and complex balancing are generally not "encoded" in the kinetic differential equations but they are realization properties that may imply local or even global asymptotic stability…

Molecular Networks · Quantitative Biology 2011-05-11 Gabor Szederkenyi , Katalin M. Hangos

We introduce a unifying and generalizing framework for complex and detailed balanced steady states in chemical reaction network theory. To this end, we generalize the graph commonly used to represent a reaction network. Specifically, we…

Dynamical Systems · Mathematics 2017-11-21 Elisenda Feliu , Daniele Cappelletti , Carsten Wiuf

This article characterizes certain small multistationary chemical reaction networks. We consider the set of fully open networks, those for which all chemical species participate in inflow and outflow, containing one non-flow (reversible or…

Dynamical Systems · Mathematics 2013-01-18 Badal Joshi

Mass-action kinetics is frequently used in systems biology to model the behaviour of interacting chemical species. Many important dynamical properties are known to hold for such systems if they are weakly reversible and have a low…

Dynamical Systems · Mathematics 2014-07-15 Matthew D. Johnston , David Siegel , Gábor Szederkényi

Within a fully microscopic setting, we derive a variational principle for the non-equilibrium steady states of chemical reaction networks, valid for time-scales over which chemical potentials can be taken to be slowly varying: at…

Molecular Networks · Quantitative Biology 2015-06-05 Andrea De Martino , Daniele De Martino , Roberto Mulet , Guido Uguzzoni

This paper considers robust stability analysis of a large network of interconnected uncertain systems. To avoid analyzing the entire network as a single large, lumped system, we model the network interconnections with integral quadratic…

Optimization and Control · Mathematics 2016-11-17 Martin S. Andersen , Anders Hansson , Sina Khoshfetrat Pakazad , Anders Rantzer

Multistationary chemical reaction networks are of interest to scientists and mathematicians alike. While some criteria for multistationarity exist, obtaining explicit reaction rates and steady states that exhibit multistationarity for a…

Dynamical Systems · Mathematics 2016-04-22 Bryan Félix , Anne Shiu , Zev Woodstock

Networks play a prominent role in the study of complex systems of interacting entities in biology, sociology, and economics. Despite this diversity, we demonstrate here that a statistical model decomposing networks into matching and…

Physics and Society · Physics 2016-02-05 Rudolf P. Rohr , Russel E. Naisbit , Christian Mazza , Louix-Félix Bersier

The detailed balance property is a fundamental property that must be satisfied in all the macroscopic systems with a well defined temperature at each point. On the other hand, many biochemical networks work in non-equilibrium conditions and…

Classical Analysis and ODEs · Mathematics 2025-02-10 E. Franco , J. J. L. Velázquez

Reliability on complex biological networks reconstructions remains a concern. Although observations are getting more and more precise, the data collection process is yet error prone and the proofs display uneven certitude. In the case of…

Molecular Networks · Quantitative Biology 2010-08-20 M. Ángeles Serrano , Francesc Sagués

We consider steady states of dynamics that have an underlying network structure. We study how a steady state responds to small perturbations in the network parameters and how this sensitivity is connected to the network structure. We…

Molecular Networks · Quantitative Biology 2023-03-20 Robin Chemnitz

Power law systems have been studied extensively due to their wide-ranging applications, particularly in chemistry. In this work, we focus on power law systems that can be decomposed into stoichiometrically independent subsystems. We show…

Dynamical Systems · Mathematics 2024-04-23 Al Jay Lan J. Alamin , Bryan S. Hernandez

We examine reaction networks (CRNs) through their associated continuous-time Markov processes. Studying the dynamics of such networks is in general hard, both analytically and by simulation. In particular, stationary distributions of…

Probability · Mathematics 2022-03-28 Linard Hoessly

We propose a novel intrinsic image decomposition network considering reflectance consistency. Intrinsic image decomposition aims to decompose an image into illumination-invariant and illumination-variant components, referred to as…

Computer Vision and Pattern Recognition · Computer Science 2021-11-09 Yuma Kinoshita , Hitoshi Kiya

We present a systematic mathematical analysis of the qualitative steady-state response to rate perturbations in large classes of reaction networks. This includes multimolecular reactions and allows for catalysis, enzymatic reactions,…

Dynamical Systems · Mathematics 2017-11-22 Bernhard Brehm , Bernold Fiedler