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A simulation strategy based in the finite element model was developed to model the corrosion and mechanical properties of biodegradable Mg scaffolds manufactured by laser power bed fusion after immersion in simulated body fluid. Corrosion…

Applied Physics · Physics 2022-01-19 Mohammad Marvi-Mashhadi , Wahaaj Ali , Muzi Li , Carlos González , Javier LLorca

Magnesium and its alloys are intriguing as possible biodegradable biomaterials due to their unique combination of biodegradability and high specific mechanical properties. However, uncontrolled biodegradation of magnesium during…

Materials Science · Physics 2016-11-16 Reece N. Oosterbeek , Christopher K. Seal , Mark P. Staiger , Margaret M. Hyland

The individual contributions of pH and chloride concentration to the corrosion kinetics of bioabsorbable magnesium (Mg) alloys remain unresolved despite their significant roles as driving factors in Mg corrosion. This study demonstrates and…

Medical Physics · Physics 2025-03-21 S. Kovacevic , W. Ali , T. K. Mandal , E. Martínez-Pañeda , J. Llorca

Magnesium alloys are emerging as promising alternatives to traditional orthopedic implant materials thanks to their biodegradability, biocompatibility, and impressive mechanical characteristics. However, their rapid in-vivo degradation…

Magnesium and its alloys are ideal for biodegradable implants due to their biocompatibility and their low-stress shielding. However, they can corrode too rapidly in the biological environment. The objective of this research was to develop…

Materials Science · Physics 2017-06-28 Sohrab Khalifeh , T. David Burleigh

Degradation data are considered for assessing reliability in highly reliable systems. The usual assumption is that degradation units come from a homogeneous population. But in presence of high variability in the manufacturing process, this…

Methodology · Statistics 2026-01-15 Barin Karmakar , Biswabrata Pradhan

We derive a mixture theory-based mathematical model of the degradation of a poroelastic solid immersed in a fluid bath. The evolution of the solid's mechanical and transport properties are also modeled. The inspiration for the model is the…

Biological Physics · Physics 2019-12-16 Priyanka Patki , Francesco Costanzo

An elastic-visco-plastic thermomechanical model for the simulation of cold forming and subsequent sintering of ceramic powders is introduced and based on micromechanical modelling of the compaction process of granulates. Micromechanics…

Computational Engineering, Finance, and Science · Computer Science 2019-07-19 D. Kempen , A. Piccolroaz , D. Bigoni

A phase-field model is developed to simulate the corrosion of Mg alloys in body fluids. The model incorporates both Mg dissolution and the transport of Mg ions in solution, naturally predicting the transition from activation-controlled to…

Medical Physics · Physics 2023-08-03 S. Kovacevic , W. Ali , E. Martínez-Pañeda , J. LLorca

In this paper we address a general parameter estimation methodology for an extended biokinetic degradation model [1] for poorly degradable micropollutants. In particular we concentrate on parameter estimation of the micropollutant…

Quantitative Methods · Quantitative Biology 2007-09-14 Monika Schoenerklee , Momtchil Peev

Sensor-based degradation signals measure the accumulation of damage of an engineering system using sensor technology. Degradation signals can be used to estimate, for example, the distribution of the remaining life of partially degraded…

Applications · Statistics 2011-07-29 Rensheng R. Zhou , Nicoleta Serban , Nagi Gebraeel

Resorbable magnesium (Mg) alloys are promising candidates for temporary medical devices due to their biodegradability and favorable mechanical properties. To accelerate the design of diluted Mg alloys for implants, we developed a…

Materials Science · Physics 2026-04-23 Vickey Nandal , Vít Beneš , Pavel Baláž , Jiří Ryjáček , Karel Tesař

Accelerated degradation tests are used to provide accurate estimation of lifetime characteristics of highly reliable products within a relatively short testing time. Data from particular tests at high levels of stress (e.g., temperature,…

Applications · Statistics 2021-06-07 Helmi Shat , Rainer Schwabe

Magnesium and its alloys are ideal candidates for biodegradable implants. However, they can dissolve too rapidly in the human body for most applications. In this research, high purified magnesium (HP-Mg) was coated with stearic acid in…

Materials Science · Physics 2017-06-30 Sohrab Khalifeh , T. David Burleigh

A combination of reaction-diffusion models with moving-boundary problems yields a system in which the diffusion (spreading and penetration) and reaction (transformation) evolve the system's state and geometry over time. These systems can be…

Computational Engineering, Finance, and Science · Computer Science 2020-08-26 Mojtaba Barzegari , Liesbet Geris

The process of calibrating computer models of natural phenomena is essential for applications in the physical sciences, where plenty of domain knowledge can be embedded into simulations and then calibrated against real observations. Current…

Machine Learning · Computer Science 2025-01-20 Rafael Oliveira , Dino Sejdinovic , David Howard , Edwin V. Bonilla

From the nano-scale to the macro-scale, biological tissue is spatially heterogeneous. Even when tissue behavior is well understood, the exact subject specific spatial distribution of material properties is often unknown. And, when…

Tissues and Organs · Quantitative Biology 2020-11-02 Emma Lejeune , Bill Zhao

A mathematical model of genome degradation is proposed that takes into account a variable rate of mutation and increasing number of cells in a developing human organism. The model explains known properties of cancer development, in…

Biological Physics · Physics 2007-05-23 V. N. Binhi

In biomanufacturing, developing an accurate model to simulate the complex dynamics of bioprocesses is an important yet challenging task. This is partially due to the uncertainty associated with bioprocesses, high data acquisition cost, and…

Machine Learning · Computer Science 2022-11-29 Yuan Sun , Winton Nathan-Roberts , Tien Dung Pham , Ellen Otte , Uwe Aickelin

Semiconductor lasers have been rapidly evolving to meet the demands of next-generation optical networks. This imposes much more stringent requirements on the laser reliability, which are dominated by degradation mechanisms (e.g., sudden…

Machine Learning · Computer Science 2022-11-08 Khouloud Abdelli , Helmut Griesser , Christian Neumeyr , Robert Hohenleitner , Stephan Pachnicke
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