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Electroanatomical mapping is a technique used in cardiology to create a detailed 3D map of the electrical activity in the heart. It is useful for diagnosis, treatment planning and real time guidance in cardiac ablation procedures to treat…
Traditional echocardiographic parameters such as ejection fraction (EF) and global longitudinal strain (GLS) have limitations in the early detection of cardiac dysfunction. EF often remains normal despite underlying pathology, and GLS is…
We propose a novel partitioned scheme based on Eikonal equations to model the coupled propagation of the electrical signal in the His-Purkinje system and in the myocardium for cardiac electrophysiology. This scheme allows, for the first…
The heart's electrical activity, recorded through Electrocardiography (ECG), is essential for diagnosing various cardiovascular conditions. However, many existing ECG segmentation models rely on complex, multi-layered architectures such as…
Cardiac digital twins (CDTs) offer personalized in-silico cardiac representations for the inference of multi-scale properties tied to cardiac mechanisms. The creation of CDTs requires precise information about the electrode position on the…
Coronary artery disease(CAD) is the most common type of heart disease and the leading cause of death worldwide[1]. A progressive state of this disease marked by plaque rupture and clot formation in the coronary arteries, also known as an…
Brain source imaging is an important method for noninvasively characterizing brain activity using Electroencephalogram (EEG) or Magnetoencephalography (MEG) recordings. Traditional EEG/MEG Source Imaging (ESI) methods usually assume that…
Objective: We seek stable Electrophysiological Source Imaging (ESI) biomarkers associated with Gait Speed (GS) as a measure of functional decline. Towards this end we determine the predictive value of ESI activation and connectivity…
This work presents a biventricular electromechanical human heart model that is comprehensive and clinically relevant, integrating a realistic 3D heart geometry with both systemic and pulmonary hemodynamics. The model uses a two-way…
Cardiac muscle cells can exhibit complex patterns including irregular behaviour such as chaos or (chaotic) early afterdepolarisations (EADs), which can lead to sudden cardiac death. Suitable mathematical models and their analysis help to…
Electroanatomical mapping, a keystone diagnostic tool in cardiac electrophysiology studies, can provide high-density maps of the local electric properties of the tissue. It is therefore tempting to use such data to better individualize…
Biosignals can be viewed as mixtures measuring particular physiological events, and blind source separation (BSS) aims to extract underlying source signals from mixtures. This paper proposes a self-supervised multi-encoder autoencoder…
Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia, and its clinical assessment requires accurate characterization of atrial electrical activity. Noninvasive electrocardiographic imaging (ECGI) combined with deep…
The shape and motion of the heart provide essential clues to understanding the mechanisms of cardiovascular disease. With the advent of large-scale cardiac imaging data, statistical atlases become a powerful tool to provide automated and…
The estimation of patient-specific tissue properties in the form of model parameters is important for personalized physiological models. However, these tissue properties are spatially varying across the underlying anatomical model,…
We present a novel microscopic tridomain model describing the electrical activity in cardiac tissue with dynamical gap junctions. The microscopic tridomain system consists of three PDEs modeling the tissue electrical conduction in the…
Cardiac cells exhibit variability in the shape and duration of their action potentials in space within a single individual. To create a mathematical model of cardiac action potentials (AP) which captures this spatial variability and also…
Electrocardiogram (ECG) signal is the most commonly used non-invasive tool in the assessment of cardiovascular diseases. Segmentation of the ECG signal to locate its constitutive waves, in particular the R-peaks, is a key step in ECG…
Epileptic seizures are transient neurological events characterized by abnormal and excessive neuron activity in the brain, which are often associated with measurable disturbances in the cardiovascular system. Traditionally,…
Electrocardiogram (ECG) is one of the non-invasive and low-risk methods to monitor the condition of the human heart. Any abnormal pattern(s) in the ECG signal is an indicative measure of malfunctioning of the heart, termed as arrhythmia.…