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Electrocardiograms (ECGs) are vital for monitoring cardiac health, enabling the assessment of heart rate variability (HRV), detection of arrhythmias, and diagnosis of cardiovascular conditions. However, ECG signals recorded from wearable…

Machine Learning · Computer Science 2025-12-17 Sharmad Kalpande , Nilesh Kumar Sahu , Haroon Lone

Inverse Uncertainty Quantification (UQ) is a process to quantify the uncertainties in random input parameters while achieving consistency between code simulations and physical observations. In this paper, we performed inverse UQ using an…

Applications · Statistics 2018-06-22 Xu Wu , Tomasz Kozlowski , Hadi Meidani , Koroush Shirvan

Deep learning has improved automated electrocardiogram (ECG) classification, but limited insight into prediction reliability hinders its use in safety-critical settings. This paper proposes UCTECG-Net, an uncertainty-aware hybrid…

Machine Learning · Computer Science 2026-02-19 Hamzeh Asgharnezhad , Pegah Tabarisaadi , Abbas Khosravi , Roohallah Alizadehsani , U. Rajendra Acharya

Parametric uncertainty in nonlinear dynamical systems can fundamentally alter bifurcation behaviour, leading to qualitative response changes. Predicting operating margins/envelopes under such uncertainties is critical but challenging:…

Dynamical Systems · Mathematics 2026-03-27 Dongxiao Hong , David A. W. Barton , Simon A. Neild

The automated analysis of medical time series, such as the electrocardiogram (ECG), electroencephalogram (EEG), pulse oximetry, etc, has the potential to serve as a valuable tool for diagnostic decisions, allowing for remote monitoring of…

Neural Network (NN) models provide potential to speed up the drug discovery process and reduce its failure rates. The success of NN models require uncertainty quantification (UQ) as drug discovery explores chemical space beyond the training…

Machine Learning · Computer Science 2022-11-01 Ya Ju Fan , Jonathan E. Allen , Kevin S. McLoughlin , Da Shi , Brian J. Bennion , Xiaohua Zhang , Felice C. Lightstone

We present PhysECG: a physically motivated projection of the 12 lead electrocardiogram, supported by a deep learning model trained on 21,799 recordings from the PTB-XL database and discuss its feasibility. The method allows to evaluate the…

The integration of photovoltaic (PV) generation and electric vehicle (EV) charging introduces significant uncertainty in electricity consumption patterns, particularly at the distribution level. This paper presents a comparative study for…

Systems and Control · Electrical Eng. & Systems 2025-12-19 Aiko Fias , Md Umar Hashmi , Geert Deconinck

Uncertainty quantification (UQ) has become critical for evaluating the reliability of artificial intelligence systems, especially in medical image segmentation. This study addresses the interpretability of instance-wise uncertainty values…

Electrocardiogram is a useful diagnostic signal that can detect cardiac abnormalities by measuring the electrical activity generated by the heart. Due to its rapid, non-invasive, and richly informative characteristics, ECG has many emerging…

Machine Learning · Computer Science 2025-12-09 Hanhui Deng , Xinglin Li , Jie Luo , Di Wu

We describe a computational framework linking Uncertainty Quantification (UQ) methods for continuum problems depending on random parameters with Equation-Free (EF) methods for performing continuum deterministic numerics by acting directly…

Dynamical Systems · Mathematics 2007-05-23 Yu Zou , Ioannis G. Kevrekidis

Uncertainty Quantification (UQ) is a key discipline for computational modeling of complex systems, enhancing reliability of engineering simulations. In crashworthiness, having an accurate assessment of the behavior of the model uncertainty…

Methodology · Statistics 2021-09-17 Marc Rocas , Alberto García-González , Sergio Zlotnik , Xabier Larráyoz , Pedro Díez

Cardiac digital twins (CDTs) of human cardiac electrophysiology (EP) are digital replicas of patient hearts that match like-for-like clinical observations. The electrocardiogram (ECG), as the most prevalent non-invasive observation of…

Medical Physics · Physics 2024-07-26 Elena Zappon , Matthias A. F. Gsell , Karli Gillette , Gernot Plank

Cardiovascular diseases, a leading cause of noncommunicable disease-related deaths, require early and accurate detection to improve patient outcomes. Taking advantage of advances in machine learning and deep learning, multiple approaches…

Computer Vision and Pattern Recognition · Computer Science 2025-02-12 Paula Ruiz-Barroso , Francisco M. Castro , José Miranda , Denisa-Andreea Constantinescu , David Atienza , Nicolás Guil

Deep learning is gaining increasing popularity for spatiotemporal forecasting. However, prior works have mostly focused on point estimates without quantifying the uncertainty of the predictions. In high stakes domains, being able to…

Artificial Intelligence · Computer Science 2021-06-15 Dongxia Wu , Liyao Gao , Xinyue Xiong , Matteo Chinazzi , Alessandro Vespignani , Yi-An Ma , Rose Yu

The objective of electrical impedance tomography is to reconstruct the internal conductivity of a physical body based on measurements of current and potential at a finite number of electrodes attached to its boundary. Although the…

Numerical Analysis · Mathematics 2016-07-04 Nuutti Hyvönen , Vesa Kaarnioja , Lauri Mustonen , Stratos Staboulis

Electrocardiography (ECG) offers critical cardiovascular insights, such as identifying arrhythmias and myocardial ischemia, but enabling automated systems to answer complex clinical questions directly from ECG signals (ECG-QA) remains a…

Signal Processing · Electrical Eng. & Systems 2025-05-13 Hung Manh Pham , Jialu Tang , Aaqib Saeed , Dong Ma

In the last few decades, uncertainty quantification (UQ) methods have been used widely to ensure the robustness of engineering designs. This chapter aims to detail recent advances in popular uncertainty quantification methods used in…

Computation · Statistics 2022-11-08 Dinesh Kumar , Farid Ahmed , Shoaib Usman , Ayodeji Alajo , Syed Alam

We propose a rigorous framework for Uncertainty Quantification (UQ) in which the UQ objectives and the assumptions/information set are brought to the forefront. This framework, which we call \emph{Optimal Uncertainty Quantification} (OUQ),…

Probability · Mathematics 2016-05-20 Houman Owhadi , Clint Scovel , Timothy John Sullivan , Mike McKerns , Michael Ortiz

Computational cardiac modelling is a mature area of biomedical computing, and is currently evolving from a pure research tool to aiding in clinical decision making. Assessing the reliability of computational model predictions is a key…

Computational Physics · Physics 2018-01-10 Rocío Rodríguez-Cantano , Joakim Sundnes , Marie E. Rognes
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