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We propose a Bayesian approach for model-based clustering of multivariate categorical data where variables are allowed to be associated within clusters and the number of clusters is unknown. The approach uses a two-layer mixture of finite…

Methodology · Statistics 2024-07-09 Gertraud Malsiner-Walli , Bettina Grün , Sylvia Frühwirth-Schnatter

Living systems have time-evolving interactions that, until recently, could not be identified accurately from recorded time series in the presence of noise. Stankovski et al. (Phys. Rev. Lett. 109 024101, 2012) introduced a method based on…

Data Analysis, Statistics and Probability · Physics 2013-01-14 Andrea Duggento , Tomislav Stankovski , Peter V. E. McClintock , Aneta Stefanovska

Neuromorphic applications emulate the processing performed by the brain by using spikes as inputs instead of time-varying analog stimuli. Therefore, these time-varying stimuli have to be encoded into spikes, which can induce important…

Neural and Evolutionary Computing · Computer Science 2024-12-30 Ahmad El Ferdaoussi , Eric Plourde , Jean Rouat

Calcium is an ubiquitous second messenger that triggers a plethora of key physiological responses. The events are initiated in micro- or nano-sized compartments and determined by the complex interactions with calcium-binding proteins and…

Subcellular Processes · Quantitative Biology 2013-05-01 S. L. Mironov

We present a comprehensive approach to the modeling, performance analysis, and design of clustered molecular nanonetworks in which nano-machines of different clusters release an appropriate number of molecules to transmit their sensed…

Information Theory · Computer Science 2023-04-11 Seyed Mohammad Azimi-Abarghouyi , Harpreet S. Dhillon , Leandros Tassiulas

Kalman filtering can provide an optimal estimation of the system state from noisy observation data. This algorithm's performance depends on the accuracy of system modeling and noise statistical characteristics, which are usually challenging…

Systems and Control · Electrical Eng. & Systems 2025-04-18 Xun Xiao , Junbo Tie , Jinyue Zhao , Ziqi Wang , Yuan Li , Qiang Dou , Lei Wang

Bayesian neural networks offer better estimates of model uncertainty compared to frequentist networks. However, inference involving Bayesian models requires multiple instantiations or sampling of the network parameters, requiring…

Neural and Evolutionary Computing · Computer Science 2024-01-30 Prabodh Katti , Anagha Nimbekar , Chen Li , Amit Acharyya , Bashir M. Al-Hashimi , Bipin Rajendran

We introduce a new supervised learning algorithm based to train spiking neural networks for classification. The algorithm overcomes a limitation of existing multi-spike learning methods: it solves the problem of interference between…

Neural and Evolutionary Computing · Computer Science 2021-08-12 Huy Le Nguyen , Dominique Chu

Sparse linear regression methods including the well-known LASSO and the Dantzig selector have become ubiquitous in the engineering practice, including in medical imaging. Among other tasks, they have been successfully applied for the…

Signal Processing · Electrical Eng. & Systems 2023-01-03 Anna Pidnebesna , Iveta Fajnerova , Jiri Horacek , Jaroslav Hlinka

In spiking neural networks, the information is conveyed by the spike times, that depend on the intrinsic dynamics of each neuron, the input they receive and on the connections between neurons. In this article we study the Markovian nature…

Applications · Statistics 2012-11-07 Jonathan Touboul , Olivier Faugeras

We describe a new, computationally simple method for analyzing the dynamics of neuronal spike trains driven by external stimuli. The goal of our method is to test the predictions of simple spike-generating models against extracellularly…

Neurons and Cognition · Quantitative Biology 2007-05-23 Daniel S. Reich , Jonathan D. Victor , Bruce W. Knight

This paper deals with the parametric inference for integrated signals embedded in an additive Gaussian noise and observed at deterministic discrete instants which are not necessarily equidistant. The unknown parameter is multidimensional…

Statistics Theory · Mathematics 2019-03-18 Dominique Dehay , Khalil El Waled , Vincent Monsan

The calcium transport in biological systems is modelled as a reaction-diffusion process. Nonlinear calcium waves are then simulated using a stochastic cellular automaton whose rules are derived from the corresponding coupled partial…

Pattern Formation and Solitons · Physics 2010-03-30 Xin-She Yang

Intensity estimation is a common problem in statistical analysis of spatial point pattern data. This paper proposes a nonparametric Bayesian method for estimating the spatial point process intensity based on mixture of finite mixture (MFM)…

Methodology · Statistics 2019-07-09 Junxian Geng , Wei Shi , Guanyu Hu

We present a method for the real time prediction of punctate events in neural activity, based on the time-frequency spectrum of the signal, applicable both to continuous processes like local field potentials (LFP) as well as to spike…

Neurons and Cognition · Quantitative Biology 2007-05-23 Hemant Bokil , Bijan Pesaran , R. A. Andersen , Partha P. Mitra

Biological systems are non-linear, include unobserved variables and the physical principles that govern their dynamics are partly unknown. This makes the characterization of their behavior very challenging. Notably, their activity occurs on…

Quantitative Methods · Quantitative Biology 2025-06-27 Andréa Ducos , Audrey Denizot , Thomas Guyet , Hugues Berry

Like many other biological processes, calcium dynamics in neurons containing an endoplasmic reticulum are governed by diffusion-reaction equations on interface-separated domains. Interface conditions are typically described by systems of…

Numerical Analysis · Mathematics 2022-03-14 Qingguang Guan , Gillian Queisser

We introduce a novel class of Bayesian mixtures for normal linear regression models which incorporates a further Gaussian random component for the distribution of the predictor variables. The proposed cluster-weighted model aims to…

Methodology · Statistics 2026-05-26 Panagiotis Papastamoulis , Konstantinos Perrakis

Understanding the interaction patterns among simultaneous recordings of spike trains from multiple neuronal units is a key topic in neuroscience. However, an optimal approach of assessing these interactions has not been established, as…

Neurons and Cognition · Quantitative Biology 2020-12-17 Gorana Mijatovic , Yuri Antonacci , Tatjana Loncar-Turukalo , Ludovico Minati , Luca Faes

This paper addresses the problem of estimating the modes of an observed non-stationary mixture signal in the presence of an arbitrary distributed noise. A novel Bayesian model is introduced to estimate the model parameters from the…

Signal Processing · Electrical Eng. & Systems 2022-03-31 Quentin Legros , Dominique Fourer , Sylvain Meignen , Marcelo A. Colominas