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In medical coding, experts map unstructured clinical notes to alphanumeric codes for diagnoses and procedures. We introduce Code Like Humans: a new agentic framework for medical coding with large language models. It implements official…

Artificial Intelligence · Computer Science 2025-10-09 Andreas Motzfeldt , Joakim Edin , Casper L. Christensen , Christian Hardmeier , Lars Maaløe , Anna Rogers

Clinical coding is a critical task in healthcare, although traditional methods for automating clinical coding may not provide sufficient explicit evidence for coders in production environments. This evidence is crucial, as medical coders…

Computation and Language · Computer Science 2025-04-08 Leonor Barreiros , Isabel Coutinho , Gonçalo M. Correia , Bruno Martins

International Classification of Diseases (ICD) are the de facto codes used globally for clinical coding. These codes enable healthcare providers to claim reimbursement and facilitate efficient storage and retrieval of diagnostic…

Computation and Language · Computer Science 2022-02-22 Pavithra Rajendran , Alexandros Zenonos , Josh Spear , Rebecca Pope

Automated international classification of diseases (ICD) coding aims to assign multiple disease codes to clinical documents and plays a critical role in healthcare informatics. However, its performance is hindered by the extreme long-tail…

Machine Learning · Computer Science 2026-01-13 Tianlei Chen , Yuxiao Chen , Yang Li , Feifei Wang

Clinical notes are unstructured text generated by clinicians during patient encounters. Clinical notes are usually accompanied by a set of metadata codes from the International Classification of Diseases(ICD). ICD code is an important code…

Artificial Intelligence · Computer Science 2021-11-12 Tak-Sung Heo , Yongmin Yoo , Yeongjoon Park , Byeong-Cheol Jo , Kyungsun Kim

Machine Learning (ML) is widely used to automatically extract meaningful information from Electronic Health Records (EHR) to support operational, clinical, and financial decision-making. However, ML models require a large number of…

Machine Learning · Computer Science 2021-04-14 Martha Dais Ferreira , Michal Malyska , Nicola Sahar , Riccardo Miotto , Fernando Paulovich , Evangelos Milios

A ubiquitous task in processing electronic medical data is the assignment of standardized codes representing diagnoses and/or procedures to free-text documents such as medical reports. This is a difficult natural language processing task…

Automatic ICD coding is the task of assigning codes from the International Classification of Diseases (ICD) to medical notes. These codes describe the state of the patient and have multiple applications, e.g., computer-assisted diagnosis or…

Computation and Language · Computer Science 2021-04-15 Damian Pascual , Sandro Luck , Roger Wattenhofer

Background and Objective: Code assignment is of paramount importance in many levels in modern hospitals, from ensuring accurate billing process to creating a valid record of patient care history. However, the coding process is tedious and…

Computation and Language · Computer Science 2019-10-03 Jinmiao Huang , Cesar Osorio , Luke Wicent Sy

Clinical coding is crucial for healthcare billing and data analysis. Manual clinical coding is labour-intensive and error-prone, which has motivated research towards full automation of the process. However, our analysis, based on US English…

Computation and Language · Computer Science 2025-06-19 Yidong Gan , Maciej Rybinski , Ben Hachey , Jonathan K. Kummerfeld

This paper addresses the challenges posed by the unstructured nature and high-dimensional semantic complexity of electronic health record texts. A deep learning method based on attention mechanisms is proposed to achieve unified modeling…

Computation and Language · Computer Science 2025-07-03 Ting Xu , Xiaoxiao Deng , Xiandong Meng , Haifeng Yang , Yan Wu

This study presents a multimodal machine learning model to predict ICD-10 diagnostic codes. We developed separate machine learning models that can handle data from different modalities, including unstructured text, semi-structured text and…

Clinical information systems have become large repositories for semi-structured and partly annotated electronic health record data, which have reached a critical mass that makes them interesting for supervised data-driven neural network…

Computation and Language · Computer Science 2023-05-22 Markus Kreuzthaler , Bastian Pfeifer , Diether Kramer , Stefan Schulz

Codification of free-text clinical narratives have long been recognised to be beneficial for secondary uses such as funding, insurance claim processing and research. The current scenario of assigning codes is a manual process which is very…

Computation and Language · Computer Science 2021-07-23 Rajvir Kaur , Jeewani Anupama Ginige , Oliver Obst

Automated ICD coding involves assigning standardized diagnostic codes to clinical narratives. The vast label space and extreme class imbalance continue to challenge precise prediction. To address these issues, LabGraph is introduced -- a…

Machine Learning · Computer Science 2026-01-13 Xiaoxiao Deng

Computerised clinical coding approaches aim to automate the process of assigning a set of codes to medical records. While there is active research pushing the state of the art on clinical coding for hospitalized patients, the outpatient…

Clinical coding is the task of transforming medical information in a patient's health records into structured codes so that they can be used for statistical analysis. This is a cognitive and time-consuming task that follows a standard…

Computation and Language · Computer Science 2022-10-11 Hang Dong , Matúš Falis , William Whiteley , Beatrice Alex , Joshua Matterson , Shaoxiong Ji , Jiaoyan Chen , Honghan Wu

Accurate clinical coding is essential for healthcare documentation, billing, and decision-making. While prior work shows that off-the-shelf LLMs struggle with this task, evaluations based on exact match metrics often overlook errors where…

Computation and Language · Computer Science 2025-10-10 Zhangdie Yuan , Han-Chin Shing , Mitch Strong , Chaitanya Shivade

Medical coding translates clinical documentation into standardized codes for billing, research, and public health, but manual coding is time-consuming and error-prone. Existing automation efforts rely on small datasets that poorly represent…

Accurate International Classification of Diseases (ICD) coding is critical for clinical documentation, billing, and healthcare analytics, yet it remains a labour-intensive and error-prone task. Although large language models (LLMs) show…

Artificial Intelligence · Computer Science 2025-09-24 Hong-Jie Dai , Zheng-Hao Li , An-Tai Lu , Bo-Tsz Shain , Ming-Ta Li , Tatheer Hussain Mir , Kuang-Te Wang , Min-I Su , Pei-Kang Liu , Ming-Ju Tsai