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Meta-analysis is a data aggregation method that establishes an overall and objective level of evidence based on the results of several studies. It is necessary to maintain a high level of homogeneity in the aggregation of data collected…

Powder bed fusion additive manufacturing (PBFAM) of metals has the potential to enable new paradigms of product design, manufacturing and supply chains while accelerating the realization of new technologies in the medical, aerospace, and…

Simulations with high accuracy are an essential part of scientific research to accelerate the innovation process. They are especially useful for finding novel approaches or optimizing existing methods. Today, powerful software tools are…

Medical Physics · Physics 2022-08-31 Patrick Vogel , Martin A. Rückert , Thomas Kampf , Volker C. Behr

We present a Quality by Design (QbD) styled approach for optimizing lipid nanoparticle (LNP) formulations, aiming to offer scientists an accessible workflow. The inherent restriction in these studies, where the molar ratios of ionizable,…

Applications · Statistics 2023-11-14 Andrew T. Karl , Sean Essex , James Wisnowski , Heath Rushing

Machine learning has become ubiquitous in materials modelling and now routinely enables large-scale atomistic simulations with quantum-mechanical accuracy. However, developing machine-learned interatomic potentials requires high-quality…

With the establishment of machine learning (ML) techniques in the scientific community, the construction of ML potential energy surfaces (ML-PES) has become a standard process in physics and chemistry. So far, improvements in the…

Chemical Physics · Physics 2024-07-23 Kai Töpfer , Luis Itza Vazquez-Salazar , Markus Meuwly

Developers of Molecular Dynamics (MD) codes face significant challenges when adapting existing simulation packages to new hardware. In a continuously diversifying hardware landscape it becomes increasingly difficult for scientists to be…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-03-14 William R. Saunders , James Grant , Eike H. Müller

Co-pyrolysis of biomass feedstocks with polymeric wastes is a promising strategy for improving the quantity and quality parameters of the resulting liquid fuel. Numerous experimental measurements are typically conducted to find the optimal…

We train an equivariant machine learning model to predict energies and forces for a real-world study of hydrogen combustion under conditions of finite temperature and pressure. This challenging case for reactive chemistry illustrates that…

Chemical Physics · Physics 2023-06-16 Xingyi Guan , Joseph Heindel , Taehee Ko , Chao Yang , Teresa Head-Gordon

The analysis of experimental results with Python often requires writing many code scripts which all need access to the same set of functions. In a common field of research, this set will be nearly the same for many users. The qspec Python…

Computational Physics · Physics 2025-03-18 Patrick Müller , Wilfried Nörtershäuser

An overview of computational methods to describe high-dimensional potential energy surfaces suitable for atomistic simulations is given. Particular emphasis is put on accuracy, computability, transferability and extensibility of the methods…

Chemical Physics · Physics 2020-07-08 Oliver T. Unke , Debasish Koner , Sarbani Patra , Silvan Käser , Markus Meuwly

The genome-scale metabolic model with protein constraint (PC-model) has been increasingly popular for microbial metabolic simulations. We present PROSO Toolbox, a unified and simple-to-use PC-model toolbox that takes any high-quality…

Molecular Networks · Quantitative Biology 2023-08-30 Haoyang Yao , Laurence Yang

Optical metasurfaces are planar arrangements of subwavelength meta-atoms that implement a wide range of transformations on incident light. The design of efficient metasurfaces requires that the responses of and interactions among meta-atoms…

Optics · Physics 2021-01-19 Mahdad Mansouree , Andrew McClung , Sarath Samudrala , Amir Arbabi

Estimating online the parameters of general state-space hidden Markov models is a topic of importance in many scientific and engineering disciplines. In this paper we present an online parameter estimation algorithm obtained by casting our…

Computation · Statistics 2016-02-25 Jimmy Olsson , Johan Westerborn

The large models, as predicted by scaling raw forecasts, have made groundbreaking progress in many fields, particularly in natural language generation tasks, where they have approached or even surpassed human levels. However, the…

Computation and Language · Computer Science 2025-04-25 Luping Wang , Sheng Chen , Linnan Jiang , Shu Pan , Runze Cai , Sen Yang , Fei Yang

Optimum filters are granted increasing recognition as valuable tools for parametric estimation in many scientific and technical fields. The DPLMS method, introduced some twenty years ago, is effective among the synthesis algorithms since it…

Instrumentation and Detectors · Physics 2023-02-17 V. D'Andrea , S. Riboldi , A. Geraci , N. Burlac , F. Salamida

We introduce a method of exploring potential energy contours in complex dynamical systems based on potentiostatic kinematics wherein the systems are evolved with minimal changes to their potential energy. We construct a simple iterative…

Computational Physics · Physics 2022-04-13 Michael J. Waters , James M. Rondinelli

A software for managing simulation jobs and results, named "OACIS", is presented. It controls a large number of simulation jobs executed in various remote servers, keeps these results in an organized way, and manages the analyses on these…

Computational Physics · Physics 2014-09-23 Yohsuke Murase , Takeshi Uchitane , Nobuyasu Ito

Foundation models and their checkpoints have significantly advanced deep learning, boosting performance across various applications. However, fine-tuned models often struggle outside their specific domains and exhibit considerable…

Complex plasmas are low-temperature plasmas that contain micrometer-size particles in addition to the neutral gas particles and the ions and electrons that make up the plasma. The microparticles interact strongly and display a wealth of…

Plasma Physics · Physics 2014-12-09 Mierk Schwabe , David B. Graves
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