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Modern studies of societal phenomena rely on the availability of large datasets capturing attributes and activities of synthetic, city-level, populations. For instance, in epidemiology, synthetic population datasets are necessary to study…

Databases · Computer Science 2016-02-26 Hao Wu , Yue Ning , Prithwish Chakraborty , Jilles Vreeken , Nikolaj Tatti , Naren Ramakrishnan

We present a Bayesian model for estimating the joint distribution of multivariate categorical data when units are nested within groups. Such data arise frequently in social science settings, for example, people living in households. The…

Methodology · Statistics 2016-10-31 Jingchen Hu , Jerome P. Reiter , Quanli Wang

Modern epidemiological analytics increasingly use machine learning models that offer strong prediction but often lack calibrated uncertainty. Bayesian methods provide principled uncertainty quantification, yet are viewed as difficult to…

Machine Learning · Statistics 2025-11-18 Debashis Chatterjee

Sharing health and behavioral data raises significant privacy concerns, as conventional de-identification methods are susceptible to privacy attacks. Differential Privacy (DP) provides formal guarantees against re-identification risks, but…

In various biomedical studies, analysis often focuses on data magnitudes, particularly when algebraic signs are irrelevant or lost. For repeated measures studies involving magnitude outcomes, incorporating random effects is essential as…

Methodology · Statistics 2025-07-16 Wen Teng , Niall D. Ferguson , Ewan C. Goligher , Anna Heath

Detecting associations between microbial compositions and sample characteristics is one of the most important tasks in microbiome studies. Most of the existing methods apply univariate models to single microbial species separately, with…

Due to increased awareness of data protection and corresponding laws many data, especially involving sensitive personal information, are not publicly accessible. Accordingly, many data collecting agencies only release aggregated data, e.g.…

Methodology · Statistics 2022-04-12 Rajbir-Singh Nirwan , Nils Bertschinger

The limited data availability due to strict privacy regulations and significant resource demands severely constrains biomedical time-series AI development, which creates a critical gap between data requirements and accessibility. Synthetic…

Machine Learning · Computer Science 2025-11-25 Youngjoon Lee , Seongmin Cho , Yehhyun Jo , Jinu Gong , Hyunjoo Jenny Lee , Joonhyuk Kang

Differential privacy allows quantifying privacy loss resulting from accessing sensitive personal data. Repeated accesses to underlying data incur increasing loss. Releasing data as privacy-preserving synthetic data would avoid this…

Machine Learning · Statistics 2021-06-10 Joonas Jälkö , Eemil Lagerspetz , Jari Haukka , Sasu Tarkoma , Antti Honkela , Samuel Kaski

Deep neural networks have become prevalent in human analysis, boosting the performance of applications, such as biometric recognition, action recognition, as well as person re-identification. However, the performance of such networks scales…

Computer Vision and Pattern Recognition · Computer Science 2022-08-22 Indu Joshi , Marcel Grimmer , Christian Rathgeb , Christoph Busch , Francois Bremond , Antitza Dantcheva

Introduction: The amount of data generated by original research is growing exponentially. Publicly releasing them is recommended to comply with the Open Science principles. However, data collected from human participants cannot be released…

Machine Learning · Statistics 2023-10-11 Rémy Chapelle , Bruno Falissard

Many modern statistical analysis and machine learning applications require training models on sensitive user data. Under a formal definition of privacy protection, differentially private algorithms inject calibrated noise into the…

Machine Learning · Statistics 2025-04-01 Yifei Xiong , Nianqiao Phyllis Ju , Sanguo Zhang

Scientific claims gain credibility by replicability, especially if replication under different circumstances and varying designs yields equivalent results. Aggregating results over multiple studies is, however, not straightforward, and when…

Methodology · Statistics 2023-12-27 Thom Benjamin Volker , Irene Klugkist

Making evidence based decisions requires data. However for real-world applications, the privacy of data is critical. Using synthetic data which reflects certain statistical properties of the original data preserves the privacy of the…

Machine Learning · Computer Science 2021-05-28 Varun Chandrasekaran , Darren Edge , Somesh Jha , Amit Sharma , Cheng Zhang , Shruti Tople

The transmission dynamics of an epidemic are rarely homogeneous. Super-spreading events and super-spreading individuals are two types of heterogeneous transmissibility. Inference of super-spreading is commonly carried out on secondary case…

Quantitative Methods · Quantitative Biology 2025-01-23 Hannah Craddock , Simon EF Spencer , Xavier Didelot

In computational biology, gene expression datasets are characterized by very few individual samples compared to a large number of measurements per sample. Thus, it is appealing to merge these datasets in order to increase the number of…

Methodology · Statistics 2011-08-18 Meili Baragatti

Many ground-breaking advancements in machine learning can be attributed to the availability of a large volume of rich data. Unfortunately, many large-scale datasets are highly sensitive, such as healthcare data, and are not widely available…

Machine Learning · Computer Science 2020-12-09 James Jordon , Alan Wilson , Mihaela van der Schaar

Trial-based economic evaluations are typically performed on cross-sectional variables, derived from the responses for only the completers in the study, using methods that ignore the complexities of utility and cost data (e.g. skewness and…

Methodology · Statistics 2018-05-21 Andrea Gabrio , Michael J. Daniels , Gianluca Baio

Mixed modeling of extreme values and random effects is relatively unexplored topic. Computational difficulties in using the maximum likelihood method for mixed models and the fact that maximum likelihood method uses available data and does…

Applications · Statistics 2019-07-05 Ali Reza Fotouhi

A common approach to synthetic data is to sample from a fitted model. We show that under general assumptions, this approach results in a sample with inefficient estimators and whose joint distribution is inconsistent with the true…

Statistics Theory · Mathematics 2026-02-18 Jordan Awan , Zhanrui Cai