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Active droplets are artificial microswimmers built from a liquid dispersion by microfluidic tools and showing self-propelled motion. These systems hold particular interest for mimicking biological phenomena, such as some aspects of cell…

Soft Condensed Matter · Physics 2023-06-14 Adriano Tiribocchi , Mihir Durve , Marco Lauricella , Andrea Montessori , Davide Marenduzzo , Sauro Succi

In vivo and in vitro systems of cells and extra-cellular matrix (ECM) systems are well known to form ordered patterns of orientationally aligned fibers. Here, we interpret them as active analogs of the (disordered) isotropic to the…

Soft Condensed Matter · Physics 2025-04-11 Haiqian Yang , Ming Guo , L. Mahadevan

In biological tissues, it is now well-understood that mechanical cues are a powerful mechanism for pattern regulation. While much work has focused on interactions between cells and external substrates, recent experiments suggest that cell…

Soft Condensed Matter · Physics 2017-11-01 Michael Czajkowski , Dapeng Bi , M. Lisa Manning , M. Cristina Marchetti

In experiments, an individual chemically active liquid crystal (LC) droplet submerged in the bulk of a surfactant solution may self-propel along a straight, helical, or random trajectory. In this paper, we develop a minimal model capturing…

Soft Condensed Matter · Physics 2019-09-16 Matvey Morozov , Sebastien Michelin

The cell cortex, a thin film of active material assembled below the cell membrane, plays a key role in cellular symmetry breaking processes such as cell polarity establishment and cell division. Here, we present a minimal model of the…

Biological Physics · Physics 2019-09-30 Alexander Mietke , V. Jemseena , K. Vijay Kumar , Ivo F. Sbalzarini , Frank Jülicher

One objective of active matter science is to unveil principles by which chaotic microscale dynamics could be transformed into useful work. A nematic liquid crystal environment offers a number of possibilities, one of which is a directional…

Soft Condensed Matter · Physics 2021-11-02 Mojtaba Rajabi , Hend Baza , Hao Wang , Oleg D. Lavrentovich

Active matter comprised of self-propelled interacting units holds a major promise for extraction of useful work from its seemingly chaotic out-of-equilibrium dynamics. Streamlining active matter to produce work is especially important at…

Soft Condensed Matter · Physics 2021-03-17 Mojtaba Rajabi , Hend Baza , Taras Turiv , Oleg D. Lavrentovich

We present a continuum level analytical model of a droplet of active contractile fluid consisting of filaments and motors. We calculate the steady state flows that result from a splayed polarisation of the filaments. We account for the…

Cell Behavior · Quantitative Biology 2014-02-20 Carl A. Whitfield , Davide Marenduzzo , Raphaël Voituriez , Rhoda J. Hawkins

Active processes drive and guide biological dynamics across scales -- from subcellular cytoskeletal remodelling, through tissue development in embryogenesis, to population-level bacterial colonies expansion. In each of these, biological…

We introduce a minimal model for a collection of self-propelled apolar active particles, also called as `active nematic', on a two-dimensional substrate and study the order-disorder transition with the variation of density. The particles…

Statistical Mechanics · Physics 2015-09-18 Rakesh Das , Manoranjan Kumar , Shradha Mishra

We numerically investigate the morphology and disclination line dynamics of active nematic droplets in three dimensions. Although our model only incorporates the simplest possible form of achiral active stress, active nematic droplets…

Soft Condensed Matter · Physics 2021-04-07 Liam J. Ruske , Julia M. Yeomans

We use linear stability analysis to show that an isotropic phase of elongated particles with dipolar flow fields can develop nematic order as a result of their activity. We argue that ordering is favoured if the particles are flow-aligning…

Soft Condensed Matter · Physics 2020-03-18 Sreejith Santhosh , Mehrana R. Nejad , Amin Doostmohammadi , Julia M. Yeomans , Sumesh P. Thampi

We extend the continuum theories of active nematohydrodynamics to model a two-fluid mixture with separate velocity fields for each fluid component, coupled through a viscous drag. The model is used to study an active nematic fluid, mixed…

Soft Condensed Matter · Physics 2023-08-02 Saraswat Bhattacharyya , Julia M. Yeomans

From the mitotic spindle up to tissues and biofilms, many biological systems behave as active droplets, which often break symmetry and change shape spontaneously. Here, I show that active nematic droplets can experience a fingering…

Soft Condensed Matter · Physics 2022-06-07 Ricard Alert

Biological cells are able to generate intricate structures and respond to external stimuli, sculpting their membrane from within. Simplified biomimetic systems can aid in understanding the principles which govern these shape changes and…

Dynamics of small particles, both living such as swimming bacteria and inanimate, such as colloidal spheres, has fascinated scientists for centuries. If one could learn how to control and streamline their chaotic motion, that would open…

Soft Condensed Matter · Physics 2023-02-08 Oleg D. Lavrentovich

Understanding and controlling the director field configuration, shape, and orientation in nematic and cholesteric liquid crystals is of fundamental importance in several branches of science. Liquid crystalline droplets, also known as…

Soft Condensed Matter · Physics 2020-12-29 Hamed Almohammadi , Massimo Bagnani , Raffaele Mezzenga

From intracellular protein trafficking to large scale motion of animal groups, the physical concepts driving the self-organization of living systems are still largely unraveled. Selforganization of active entities, leading to novel phases…

Soft Condensed Matter · Physics 2019-11-12 Benoit Vincenti , Gabriel Ramos , Maria Luisa Cordero , Carine Douarche , Rodrigo Soto , Eric Clément

Active gels are a class of biologically-relevant material containing embedded agents that spontaneously generate forces acting on a sparse filament network. In vitro experiments of protein filaments and molecular motors have revealed a…

Soft Condensed Matter · Physics 2024-06-03 David A. Head , Gerhard Gompper , W. J. Briels

With exquisite precision and reproducibility, cells orchestrate the cooperative action of thousands of nanometer-sized molecular motors to carry out mechanical tasks at much larger length scales, such as cell motility, division and…

Soft Condensed Matter · Physics 2013-01-08 Tim Sanchez , Daniel T. N. Chen , Stephen J. DeCamp , Michael Heymann , Zvonimir Dogic