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This study investigates the speech articulatory coordination in schizophrenia subjects exhibiting strong positive symptoms (e.g. hallucinations and delusions), using two distinct channel-delay correlation methods. We show that the…

Audio and Speech Processing · Electrical Eng. & Systems 2023-05-18 Yashish M. Siriwardena , Chris Kitchen , Deanna L. Kelly , Carol Espy-Wilson

Advances in artificial intelligence (AI) and deep learning have improved diagnostic capabilities in healthcare, yet limited interpretability continues to hinder clinical adoption. Schizophrenia, a complex disorder with diverse symptoms…

Audio and Speech Processing · Electrical Eng. & Systems 2025-11-06 Gowtham Premananth , Carol Espy-Wilson

Automatic recognition of disordered speech remains a highly challenging task to date. Sources of variability commonly found in normal speech including accent, age or gender, when further compounded with the underlying causes of speech…

Sound · Computer Science 2022-01-20 Mengzhe Geng , Shansong Liu , Jianwei Yu , Xurong Xie , Shoukang Hu , Zi Ye , Zengrui Jin , Xunying Liu , Helen Meng

Depression detection using vocal biomarkers is a highly researched area. Articulatory coordination features (ACFs) are developed based on the changes in neuromotor coordination due to psychomotor slowing, a key feature of Major Depressive…

Audio and Speech Processing · Electrical Eng. & Systems 2021-04-12 Nadee Seneviratne , Carol Espy-Wilson

This study focuses on how different modalities of human communication can be used to distinguish between healthy controls and subjects with schizophrenia who exhibit strong positive symptoms. We developed a multi-modal schizophrenia…

Signal Processing · Electrical Eng. & Systems 2024-04-22 Gowtham Premananth , Yashish M. Siriwardena , Philip Resnik , Carol Espy-Wilson

Multi-resolution spectro-temporal features of a speech signal represent how the brain perceives sounds by tuning cortical cells to different spectral and temporal modulations. These features produce a higher dimensional representation of…

Audio and Speech Processing · Electrical Eng. & Systems 2022-06-28 Rahil Parikh , Nadee Seneviratne , Ganesh Sivaraman , Shihab Shamma , Carol Espy-Wilson

Despite the rapid progress of automatic speech recognition (ASR) technologies targeting normal speech in recent decades, accurate recognition of dysarthric and elderly speech remains highly challenging tasks to date. Sources of…

Audio and Speech Processing · Electrical Eng. & Systems 2022-03-18 Mengzhe Geng , Xurong Xie , Zi Ye , Tianzi Wang , Guinan Li , Shujie Hu , Xunying Liu , Helen Meng

Psychomotor retardation associated with depression has been linked with tangible differences in vowel production. This paper investigates a knowledge-driven machine learning (ML) method that integrates spectrotemporal information of speech…

Machine Learning · Computer Science 2022-10-07 Kexin Feng , Theodora Chaspari

Speech-based assessment of the schizophrenia spectrum has been widely researched over in the recent past. In this study, we develop a deep learning framework to estimate schizophrenia severity scores from speech using a feature fusion…

Audio and Speech Processing · Electrical Eng. & Systems 2024-11-21 Gowtham Premananth , Carol Espy-Wilson

Purpose: This study evaluated whether articulatory kinematics, inferred by Articulatory Phonology speech inversion neural networks, aligned with perceptual ratings of /r/ and /s/ in the speech of children with speech sound disorders.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-07-03 Nina R. Benway , Saba Tabatabaee , Dongliang Wang , Benjamin Munson , Jonathan L. Preston , Carol Espy-Wilson

[See full abstract in the pdf] Formal Thought Disorder (FTD), which is a group of symptoms in cognition that affects language and thought, can be observed through language. FTD is seen across such developmental or psychiatric disorders as…

Computation and Language · Computer Science 2023-10-17 Takeshi Saga , Hiroki Tanaka , Satoshi Nakamura

Understanding the relationship between tongue motion patterns during speech and their resulting speech acoustic outcomes -- i.e., articulatory-acoustic relation -- is of great importance in assessing speech quality and developing innovative…

Auditory verbal hallucinations (AVH) in schizophrenia (SZ) have been associated with abnormalities of the left arcuate fasciculus and transcallosal white matter projections linking homologous language areas of both hemispheres. While most…

Neurons and Cognition · Quantitative Biology 2022-11-18 Fanny Thomas , Cécile Gallea , Virginie Moulier , Noomane Bouaziz , Antoni Valero-Cabré , Dominique Januel

Embedded in any speech signal is a rich combination of cognitive, neuromuscular and physiological information. This richness makes speech a powerful signal in relation to a range of different health conditions, including major depressive…

Sound · Computer Science 2022-04-04 Salvatore Fara , Stefano Goria , Emilia Molimpakis , Nicholas Cummins

This paper presents a novel multimodal framework to distinguish between different symptom classes of subjects in the schizophrenia spectrum and healthy controls using audio, video, and text modalities. We implemented Convolution Neural…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-17 Gowtham Premananth , Yashish M. Siriwardena , Philip Resnik , Sonia Bansal , Deanna L. Kelly , Carol Espy-Wilson

Empirical studies over the past two decades have supported the hypothesis that schizophrenia is characterized by altered connectivity patterns in functional brain networks. These alterations have been proposed as genetically-mediated…

Neurons and Cognition · Quantitative Biology 2013-06-28 Felix Siebenhuhner , Shennan A. Weiss , Richard Coppola , Daniel R. Weinberger , Danielle S. Bassett

Articulatory-to-acoustic inversion strongly depends on the type of data used. While most previous studies rely on EMA, which is limited by the number of sensors and restricted to accessible articulators, we propose an approach aiming at a…

Audio and Speech Processing · Electrical Eng. & Systems 2026-03-31 Sofiane Azzouz , Pierre-André Vuissoz , Yves Laprie

Key features of mental illnesses are reflected in speech. Our research focuses on designing a multimodal deep learning structure that automatically extracts salient features from recorded speech samples for predicting various mental…

Machine Learning · Computer Science 2020-04-15 Habibeh Naderi , Behrouz Haji Soleimani , Stan Matwin

Natural language processing tools are used to automatically detect disturbances in transcribed speech of schizophrenia inpatients who speak Hebrew. We measure topic mutation over time and show that controls maintain more cohesive speech…

Computation and Language · Computer Science 2019-04-18 Kfir Bar , Vered Zilberstein , Ido Ziv , Heli Baram , Nachum Dershowitz , Samuel Itzikowitz , Eiran Vadim Harel

Adults who are minimally verbal with autism spectrum disorder (mvASD) have pronounced speech difficulties linked to impaired motor skills. Existing research and clinical assessments primarily use indirect methods such as standardized tests,…

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