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Intracellular processes triggered by neural activity include changes in ionic concentrations, protein release, and synaptic vesicle cycling. These processes play significant roles in neurological disorders. The beneficial effects of brain…

Neurons and Cognition · Quantitative Biology 2024-09-26 Saeed Omidi , Gianluca Fabi , Xiaopeng Wang , James C. M. Hwang , Yevgeny Berdichevsky

When the human brain manifests the birth of organised communication among local and large-scale neuronal populations activity remains undescribed. We report, in resting-state EEG source-estimates of 100 infants at term age, the existence of…

Neurons and Cognition · Quantitative Biology 2020-09-08 Steve Mehrkanoon

Many natural systems are organized as networks, in which the nodes (be they cells, individuals or populations) interact in a time-dependent fashion. The dynamic behavior of these networks depends on how these nodes are connected, which can…

Neurons and Cognition · Quantitative Biology 2015-06-22 Anca Radulescu , Sergio Verduzco-Flores

Our ability to track multiple objects in a dynamic environment enables us to perform everyday tasks such as driving, playing team sports, and walking in a crowded mall. Despite more than three decades of literature on multiple object…

Neurons and Cognition · Quantitative Biology 2022-08-01 Yannick Roy , Jocelyn Faubert

Author summary: Synchronization of neuronal spiking in the brain is related to cognitive functions, such as perception, attention, and memory. It is therefore important to determine which properties of neurons influence their collective…

Neurons and Cognition · Quantitative Biology 2013-11-06 Josef Ladenbauer , Moritz Augustin , LieJune Shiau , Klaus Obermayer

Mobility is severely impacted in patients with Parkinson's disease (PD), especially when they experience involuntary stopping from the freezing of gait (FOG). Understanding the neurophysiological difference between "voluntary stopping" and…

When brain signals are recorded in an electroencephalogram or some similar large-scale record of brain activity, oscillatory patterns are typically observed that are thought to reflect the aggregate electrical activity of the underlying…

Neurons and Cognition · Quantitative Biology 2013-06-04 Andre Nathan , Valmir C. Barbosa

Bursting neurons are considered to be a potential cause of over-excitability and seizure susceptibility. The functional influence of these neurons in extended epileptic networks is still poorly understood. There is mounting evidence that…

Neurons and Cognition · Quantitative Biology 2016-10-07 Christian Geier , Alexander Rothkegel , Christian E. Elger , Klaus Lehnertz

We study analytically the dynamics of a network of sparsely connected inhibitory integrate-and-fire neurons in a regime where individual neurons emit spikes irregularly and at a low rate. In the limit when the number of neurons N tends to…

Disordered Systems and Neural Networks · Physics 2007-05-23 N. Brunel , V. Hakim

Neuronal correlates of Parkinson's disease (PD) include a slowing of the electroencephalogram (EEG) and enhanced synchrony at 3-7 and 7-30 Hz in the basal ganglia, thalamus, and cortex. This study describes the dynamics of a physiologically…

Neurons and Cognition · Quantitative Biology 2018-01-08 Sacha Jennifer van Albada , Richard T. Gray , Peter M. Drysdale , Peter A. Robinson

Cognitive function depends on an adaptive balance between flexible dynamics and integrative processes in distributed cortical networks. Patterns of zero-lag synchrony likely underpin numerous perceptual and cognitive functions.…

Neurons and Cognition · Quantitative Biology 2014-09-16 Leonardo L. Gollo , Michael Breakspear

We show that the unavoidable increase in neuronal response latency to ongoing stimulation serves as a nonuniform gradual stretching of neuronal circuit delay loops and emerges as an essential mechanism in the formation of various types of…

Neurons and Cognition · Quantitative Biology 2012-12-07 Roni Vardi , Reut Timor , Shimon Marom , Moshe Abeles , Ido Kanter

Interactions in nature can be described by their coupling strength, direction of coupling and coupling function. The coupling strength and directionality are relatively well understood and studied, at least for two interacting systems,…

Adaptation and Self-Organizing Systems · Physics 2017-02-09 Tomislav Stankovski

While differences in patterns of functional connectivity and neural synchronization have been reported between individuals on the autism spectrum and neurotypical peers at various age stages, these differences appear to be subtle and may…

Neurons and Cognition · Quantitative Biology 2025-07-15 Sungwoo Ahn , Leonid L Rubchinsky , Evie A Malaia

In neural circuits, synaptic strengths influence neuronal activity by shaping network dynamics, and neuronal activity influences synaptic strengths through activity-dependent plasticity. Motivated by this fact, we study a recurrent-network…

Neurons and Cognition · Quantitative Biology 2024-01-12 David G. Clark , L. F. Abbott

EEG slowing is reported in various neurological disorders including Alzheimer's, Parkinson's and Epilepsy. Here, we investigate alpha rhythm slowing in individuals with refractory temporal lobe epilepsy (TLE), compared to healthy controls,…

Epilepsy is one of the most common neurological disorders globally, affecting millions of individuals. Despite significant advancements, the precise mechanisms underlying this condition remain largely unknown, making accurately predicting…

Systems and Control · Electrical Eng. & Systems 2024-04-05 Yuzhen Qin , Ahmed El-Gazzar , Danielle S. Bassett , Fabio Pasqualetti , Marcel van Gerven

In this report trial-to-trial variations in the synchronized responses of neural networks are offered as evidence for excitation-inhibition ratio being a dynamic variable over time scales of minutes. Synchronized network responses to…

Neurons and Cognition · Quantitative Biology 2015-01-05 Netta Haroush , Shimon Marom

Neuronal and glial cells release diverse proteoglycans and glycoproteins, which aggregate in the extracellular space and form the extracellular matrix (ECM) that may in turn regulate major cellular functions. Brain cells also release…

Neurons and Cognition · Quantitative Biology 2018-07-18 Ivan Lazarevich , Sergey Stasenko , Maia Rozhnova , Evgeniya Pankratova , Alexander Dityatev , Victor Kazantsev

The idealisation of neuronal pulses as $\delta$-spikes is a convenient approach in neuroscience but can sometimes lead to erroneous conclusions. We investigate the effect of a finite pulse-width on the dynamics of balanced neuronal…

Neurons and Cognition · Quantitative Biology 2024-06-19 Afifurrahman , Ekkehard Ullner , Antonio Politi