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X-ray Bragg coherent diffraction imaging has been demonstrated as a powerful three-dimensional (3D) microscopy approach for the investigation of sub-micrometer-scale crystalline particles. It is based on the measurement of a series of…

Regularization methods are commonly used in X-ray CT image reconstruction. Different regularization methods reflect the characterization of different prior knowledge of images. In a recent work, a new regularization method called a…

Medical Physics · Physics 2017-04-18 Wenxiang Cong , Ge Wang , Qingsong Yang , Jiang Hsieh , Jia Li , Rongjie Lai

The Spallation Neutron Source (SNS) at Oak Ridge National Laboratory (ORNL) operates in the event mode. Time-of-flight (TOF) information about each detected neutron is collected separately and saved as a descriptive entry in a database…

Materials Science · Physics 2024-06-11 Viktor Reshniak , Xiaoping Wang , Guannan Zhang , Siyan Liu , Junqi Yin

The advent of advanced crystallographic techniques has shifted structural biology from static, single-conformer models toward probing protein dynamics. Extracting cooperative motions from temporally and spatially averaged electron density…

Quantitative Methods · Quantitative Biology 2025-09-08 Avinash Mandaiya , Veit Elser

We demonstrate a neutron tomography technique with sub-micrometer spatial resolution. Our method consists of measuring neutron diffraction spectra using a double crystal diffractometer as a function of sample rotation and then using a phase…

Instrumentation and Detectors · Physics 2020-11-13 B. Heacock , D. Sarenac , D. G. Cory , M. G. Huber , J. P. W. MacLean , H. Miao , H. Wen , D. A. Pushin

In a number of tomographic applications, data cannot be fully acquired, resulting in a severely underdetermined image reconstruction. In such cases, conventional methods lead to reconstructions with significant artifacts. To overcome these…

Numerical Analysis · Mathematics 2023-06-21 Simon Göppel , Jürgen Frikel , Markus Haltmeier

The use of ray projections to reconstruct images is a common technique in medical imaging. Dealing with incomplete data is particularly important when a patient is vulnerable to potentially damaging radiation or is unable to cope with the…

Neural and Evolutionary Computing · Computer Science 2024-06-04 Mohammad Majid al-Rifaie , Tim Blackwell

We are currently conceiving, through (MC) simulation, a multi-channel gamma detector array (TIARA for Time-of-flight Imaging ARrAy) for the online monitoring of protontherapy treatments. By measuring the Time-Of-Flight (TOF) between a beam…

Classical reconstruction methods for phase-contrast tomography consist of two stages: phase retrieval and tomographic reconstruction. A novel algebraic method combining the two was suggested by Kostenko et al. (Opt. Express, 21, 12185,…

Numerical Analysis · Computer Science 2015-09-08 Rasmus Dalgas Kongskov , Jakob Sauer Jørgensen , Henning Friis Poulsen , Per Christian Hansen

In this paper we present a novel iterative procedure for multichannel image and data reconstruction using Bregman distances. With the motivation that multiple channels sharing a common subgradient with respect to a suitable regularization…

Numerical Analysis · Mathematics 2014-12-18 Michael Moeller , Eva-Maria Brinkmann , Martin Burger , Tamara Seybold

Propagation-based neutron phase-contrast tomography was demonstrated using the ISIS pulsed spallation source. The proof-of-concept tomogram with Paganin-type phase-retrieval filter applied exhibited an effective net boost of $23\pm 1$ in…

Image and Video Processing · Electrical Eng. & Systems 2023-07-31 David M. Paganin , Morten Sales , Peter M. Kadletz , Winfried Kockelmann , Mario A. Beltran , Henning F. Poulsen , Søren Schmidt

All imaging modalities such as computed tomography (CT), emission tomography and magnetic resonance imaging (MRI) require a reconstruction approach to produce an image. A common image processing task for applications that utilise those…

Spectral Computed Tomography (CT) is an emerging technology that enables to estimate the concentration of basis materials within a scanned object by exploiting different photon energy spectra. In this work, we aim at efficiently solving a…

Optimization and Control · Mathematics 2021-03-26 Alessandro Perelli , Martin S. Andersen

We propose a model-based image reconstruction method for photoacoustic tomography(PAT) involving a novel form of regularization and demonstrate its ability to recover good quality images from significantly reduced size datasets. The…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Nadaparambil Aravindakshan Rejesh , Sandeep Kumar Kalva , Manojit Pramanik , Muthuvel Arigovindan

We present a general analytic approach to spatially resolve the nano-scale lattice distortion field of strained and defected compact crystals with Bragg coherent x-ray diffraction imaging (BCDI). Our approach relies on fitting a…

Bragg coherent diffraction imaging (BCDI) phase retrieval becomes rapidly difficult in the strong-phase regime, where a crystal contains distortions beyond half a lattice spacing. An important special case is the phase domain problem, where…

Optics · Physics 2026-02-13 Jialun Liu , David Yang , Ian Robinson

High radiation dose in CT scans increases a lifetime risk of cancer and has become a major clinical concern. Recently, iterative reconstruction algorithms with Total Variation (TV) regularization have been developed to reconstruct CT images…

Medical Physics · Physics 2015-05-19 Zhen Tian , Xun Jia , Kehong Yuan , Tinsu Pan , Steve B. Jiang

Based on phase retrieval, lensless coherent imaging and in particular holography offers quantitative phase and amplitude images. This is of particular importance for spectral ranges where suitable lenses are challenging, such as for hard…

Image and Video Processing · Electrical Eng. & Systems 2022-09-01 Simon Huhn , Leon Merten Lohse , Jens Lucht , Tim Salditt

The physical properties of polycrystalline materials depend on their microstructure, which is the nano-to-centimeter-scale arrangement of phases and defects in their interior. Such microstructure depends on the shape, crystallographic phase…

Multilayer position-sensitive 10B-RPC thermal neutron detectors offer an attractive combination of sub-millimeter spatial resolution and high (>50%) detection efficiency. Here we describe a new position reconstruction method based on a…

Instrumentation and Detectors · Physics 2021-09-01 A. Morozov , L. M. S. Margato , V. Solovov , A. Blanco , J. Saraiva , T. Wilpert , K. Zeitelhack , K. Roemer , C. Höglund , L. Robinson , R. Hall-Wilton