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Estimating a causal query from observational data is an essential task in the analysis of biomolecular networks. Estimation takes as input a network topology, a query estimation method, and observational measurements on the network…

Estimation of causal effects involves crucial assumptions about the data-generating process, such as directionality of effect, presence of instrumental variables or mediators, and whether all relevant confounders are observed. Violation of…

Machine Learning · Computer Science 2021-09-01 Amit Sharma , Vasilis Syrgkanis , Cheng Zhang , Emre Kıcıman

Do-calculus is concerned with estimating the interventional distribution of an action from the observed joint probability distribution of the variables in a given causal structure. All identifiable causal effects can be derived using the…

Methodology · Statistics 2018-06-20 Santtu Tikka , Juha Karvanen

Large language models (LLMs) are increasingly being applied to tasks that involve causal reasoning. However, current benchmarks often rely on string matching or surface-level metrics that do not capture whether the output of a model is…

Artificial Intelligence · Computer Science 2026-01-30 Paul He , Yinya Huang , Mrinmaya Sachan , Zhijing Jin

We prove the main rules of causal calculus (also called do-calculus) for i/o structural causal models (ioSCMs), a generalization of a recently proposed general class of non-/linear structural causal models that allow for cycles, latent…

Machine Learning · Statistics 2022-08-31 Patrick Forré , Joris M. Mooij

Using deep latent variable models in causal inference has attracted considerable interest recently, but an essential open question is their ability to yield consistent causal estimates. While they have demonstrated promising results and…

Machine Learning · Computer Science 2022-01-25 Severi Rissanen , Pekka Marttinen

The standard approach to answering an identifiable causal-effect query (e.g., $P(Y|do(X)$) when given a causal diagram and observational data is to first generate an estimand, or probabilistic expression over the observable variables, which…

Artificial Intelligence · Computer Science 2024-08-28 Anna Raichev , Alexander Ihler , Jin Tian , Rina Dechter

Objective: The growing availability of large-scale observational clinical datasets and challenges in conducting randomized controlled trials have spurred enthusiasm in using causal machine learning (ML) for causal inference in observational…

In addition to efficient statistical estimators of a treatment's effect, successful application of causal inference requires specifying assumptions about the mechanisms underlying observed data and testing whether they are valid, and to…

Methodology · Statistics 2020-11-10 Amit Sharma , Emre Kiciman

The do-calculus is a well-known deductive system for deriving connections between interventional and observed distributions, and has been proven complete for a number of important identifiability problems in causal inference. Nevertheless,…

Methodology · Statistics 2019-03-12 Daniel Malinsky , Ilya Shpitser , Thomas Richardson

Deep learning vulnerability detection has shown promising results in recent years. However, an important challenge that still blocks it from being very useful in practice is that the model is not robust under perturbation and it cannot…

Software Engineering · Computer Science 2024-01-17 Md Mahbubur Rahman , Ira Ceka , Chengzhi Mao , Saikat Chakraborty , Baishakhi Ray , Wei Le

Knowing the effect of an intervention is critical for human decision-making, but current approaches for causal effect estimation rely on manual data collection and structuring, regardless of the causal assumptions. This increases both the…

Machine Learning · Computer Science 2024-10-29 Nikita Dhawan , Leonardo Cotta , Karen Ullrich , Rahul G. Krishnan , Chris J. Maddison

Epidemiological evidence is based on multiple data sources including clinical trials, cohort studies, surveys, registries and expert opinions. Merging information from different sources opens up new possibilities for the estimation of…

Applications · Statistics 2024-07-03 Juha Karvanen , Santtu Tikka , Antti Hyttinen

Recent claims of strong performance by Large Language Models (LLMs) on causal discovery are undermined by a key flaw: many evaluations rely on benchmarks likely included in pretraining corpora. Thus, apparent success suggests that LLM-only…

Causal learning has long concerned itself with the accurate recovery of underlying causal mechanisms. Such causal modelling enables better explanations of out-of-distribution data. Prior works on causal learning assume that the high-level…

Estimation of causal effects is fundamental in situations were the underlying system will be subject to active interventions. Part of building a causal inference engine is defining how variables relate to each other, that is, defining the…

Methodology · Statistics 2021-03-02 Sergio Garrido , Stanislav S. Borysov , Jeppe Rich , Francisco C. Pereira

The concept of causality has a controversial history. The question of whether it is possible to represent and address causal problems with probability theory, or if fundamentally new mathematics such as the do-calculus is required has been…

Machine Learning · Statistics 2019-10-22 Finnian Lattimore , David Rohde

Latent variable models provide a powerful framework for incorporating and inferring unobserved factors in observational data. In causal inference, they help account for hidden factors influencing treatment or outcome, thereby addressing…

Machine Learning · Computer Science 2025-08-29 Tetsuro Morimura , Tatsushi Oka , Yugo Suzuki , Daisuke Moriwaki

Causal effect identification considers whether an interventional probability distribution can be uniquely determined without parametric assumptions from measured source distributions and structural knowledge on the generating system. While…

Machine Learning · Statistics 2021-08-30 Santtu Tikka , Antti Hyttinen , Juha Karvanen

Learning individual-level causal effects from observational data, such as inferring the most effective medication for a specific patient, is a problem of growing importance for policy makers. The most important aspect of inferring causal…

Machine Learning · Statistics 2017-11-07 Christos Louizos , Uri Shalit , Joris Mooij , David Sontag , Richard Zemel , Max Welling
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