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Related papers: Optimal Lockdown Policy for Covid-19: A Modelling …

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Testing is a crucial control mechanism in the beginning phase of an epidemic when the vaccines are not yet available. It enables the public health authority to detect and isolate the infected cases from the population, thereby limiting the…

After the introduction of drastic containment measures aimed at stopping the epidemic contagion from SARS-CoV2, many governments have adopted a strategy based on a periodic relaxation of such measures in the face of a severe economic crisis…

Populations and Evolution · Quantitative Biology 2021-06-10 Giacomo Albi , Lorenzo Pareschi , Mattia Zanella

After the COVID-19 pandemic, we saw an increase in demand for epidemiological mathematical models. The goal of this work is to study the optimal control for an age-structured model as a strategy of quarantine of infected people, which is…

Optimization and Control · Mathematics 2024-11-04 Nelson L. Santos Junior , João A. M. Gondim

Given maximal social distancing duration and intensity, how can one minimize the epidemic final size, or equivalently the total number of individuals infected during the outbreak? A complete answer to this question is provided and…

Optimization and Control · Mathematics 2020-10-01 Pierre-Alexandre Bliman , Michel Duprez

To reduce the impact of COVID-19 pandemic most countries have implemented several counter-measures to control the virus spread including school and border closing, shutting down public transport and workplace and restrictions on gathering.…

Social and Information Networks · Computer Science 2020-09-14 Ahmed Ben Said , Abdelkarim Erradi , Hussein Aly , Abdelmonem Mohamed

We analyze an approach to managing the COVID-19 pandemic without shutting down the economy while staying within the capacity of the healthcare system. We base our analysis on a detailed heterogeneous epidemiological model, which takes into…

Populations and Evolution · Quantitative Biology 2020-05-12 David Gershon , Alexander Lipton , Hagai Levine

This study explores the application of Pontryagin's Maximum Principle to derive optimal strategies for controlling the spread of COVID-19, leveraging a novel compartmental model to capture the disease dynamics. We prioritize three key…

As of December 2020, the COVID-19 pandemic has infected over 75 million people, making it the deadliest pandemic in modern history. This study develops a novel compartmental epidemiological model specific to the SARS-CoV-2 virus and…

Populations and Evolution · Quantitative Biology 2021-11-19 Caden Lin

In this paper, we propose a two-group SIR epidemic model to simulate the outcome of stay-at-home policy and wearing face masks during the first COVID-19 epidemic wave in the United States. Based on our proposed model, we further use the…

Populations and Evolution · Quantitative Biology 2021-01-11 Jun Liu , Xiang-Sheng Wang

A mathematical model for the COVID-19 pandemic spread, which integrates age-structured Susceptible-Exposed-Infected-Recovered-Deceased dynamics with real mobile phone data accounting for the population mobility, is presented. The dynamical…

Applications · Statistics 2021-08-24 Ritabrata Dutta , Susana Gomes , Dante Kalise , Lorenzo Pacchiardi

This paper analyses the optimal control of infectious disease propagation using a classic susceptible-infected-recovered (SIR) model characterised by permanent immunity and the absence of available vaccines. The control is performed over a…

Optimization and Control · Mathematics 2024-06-12 Rocío Balderrama , Mariana Inés Prieto , Constanza Sánchez de la Vega , Federico Vazquez

Given multiple new COVID-19 variants are continuously emerging, non-pharmaceutical interventions are still primary control strategies to curb the further spread of coronavirus. However, implementing strict interventions over extended…

Populations and Evolution · Quantitative Biology 2022-03-01 Xiao Zhou , Xiaohu Zhang , Paolo Santi , Carlo Ratti

The dynamics of epidemics depend on how people's behavior changes during an outbreak. At the beginning of the epidemic, people do not know about the virus, then, after the outbreak of epidemics and alarm, they begin to comply with the…

Physics and Society · Physics 2021-11-29 I. A. Kastalskiy , E. V. Pankratova , E. M. Mirkes , V. B. Kazantsev , A. N. Gorban

After the first lockdown in response to the COVID-19 outbreak, many countries faced difficulties in balancing infection control with economics. Due to limited prior knowledge, economists began researching this issue using cost-benefit…

Populations and Evolution · Quantitative Biology 2021-10-19 Tsuyoshi Hondou

In this study, we present an epidemic-controlled SIRD model with two types of control strategies: mask wear and screening. The aim of this study is to minimize the number of deceased keeping a minimal cost of mask advertising and screening.…

Populations and Evolution · Quantitative Biology 2021-09-06 Amira Bouhali , Walid Ben Aribi , Slimane Ben Miled , Amira Kebir

The COVID-19 crisis has shown that we can only prevent the risk of mass contagion through timely, large-scale, coordinated, and decisive actions. However, frequently the models used by experts [from whom decision-makers get their main…

Applications · Statistics 2021-03-08 Mauricio Herrera

This article considers the minimization of the total number of infected individuals over the course of an epidemic in which the rate of infectious contacts can be reduced by time-dependent nonpharmaceutical interventions. The societal and…

Optimization and Control · Mathematics 2023-03-16 Tom Britton , Lasse Leskelä

Social distancing and lockdown are the two main non-pharmaceutical interventions being used by the UK government to contain and control the COVID-19 epidemic; these are being applied uniformly across the entire country, even though the…

Populations and Evolution · Quantitative Biology 2020-04-28 L C G Rogers

The COVID-19 pandemic due to the SARS-CoV-2 coronavirus has directly impacted the public health and economy worldwide. To overcome this problem, countries have adopted different policies and non-pharmaceutical interventions for controlling…

When effective medical treatment and vaccination are not available, non-pharmaceutical interventions such as social distancing, home quarantine and far-reaching shutdown of public life are the only available strategies to prevent the spread…

Populations and Evolution · Quantitative Biology 2020-08-19 Markus Kantner , Thomas Koprucki