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In this work we present a flexible, probabilistic and reference-free method of error correction for high throughput DNA sequencing data. The key is to exploit the high coverage of sequencing data and model short sequence outputs as…

Information Theory · Computer Science 2013-02-04 Xin Yin , Zhao Song , Karin Dorman , Aditya Ramamoorthy

The hidden Markov model (HMM) is a fundamental tool for sequence modeling that cleanly separates the hidden state from the emission structure. However, this separation makes it difficult to fit HMMs to large datasets in modern NLP, and they…

Computation and Language · Computer Science 2020-11-10 Justin T. Chiu , Alexander M. Rush

Maximum a posteriori (MAP) inference is an important task for graphical models. Due to complex dependencies among variables in realistic model, finding an exact solution for MAP inference is often intractable. Thus, many approximation…

Machine Learning · Computer Science 2020-01-22 Baoyuan Wu , Li Shen , Tong Zhang , Bernard Ghanem

To estimate the emission parameters in hidden Markov models one commonly uses the EM algorithm or its variation. Our primary motivation, however, is the Philips speech recognition system wherein the EM algorithm is replaced by the Viterbi…

Statistics Theory · Mathematics 2007-09-17 J. Lember , A. Koloydenko

The paper describes an improved parallel MPI-based implementation of VBARMS, a variable block variant of the pARMS preconditioner proposed by Li,~Saad and Sosonkina [NLAA, 2003] for solving general nonsymmetric linear systems. The parallel…

Numerical Analysis · Mathematics 2015-08-11 Bruno Carpentieri , Jia Liao , Masha Sosonkina , Aldo Bonfiglioli

With the rapid growth of large language models (LLMs), a wide range of methods have been developed to distribute computation and memory across hardware devices for efficient training and inference. While existing surveys provide descriptive…

Machine Learning · Computer Science 2026-02-11 Hossam Amer , Rezaul Karim , Ali Pourranjbar , Weiwei Zhang , Walid Ahmed , Boxing Chen

Bayesian inference for hierarchical models can be very challenging. MCMC methods have difficulty scaling to large models with many observations and latent variables. While variational inference (VI) and reweighted wake-sleep (RWS) can be…

Machine Learning · Statistics 2025-03-12 Thomas Heap , Sam Bowyer , Laurence Aitchison

We investigate a novel modeling approach for end-to-end neural network training using hidden Markov models (HMM) where the transition probabilities between hidden states are modeled and learned explicitly. Most contemporary…

Machine Learning · Computer Science 2023-10-10 Daniel Mann , Tina Raissi , Wilfried Michel , Ralf Schlüter , Hermann Ney

Matrix multiplication is a fundamental computation in many scientific disciplines. In this paper, we show that novel fast matrix multiplication algorithms can significantly outperform vendor implementations of the classical algorithm and…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-01-08 Austin R. Benson , Grey Ballard

This paper presents an algorithm for sampling random variables that allows to separation of the sampling process into subproblems by dividing the sample space into overlapping parts. The subproblems can be solved independently of each other…

Computation · Statistics 2016-01-26 Jonas Hallgren , Timo Koski

As it has become common to use many computer cores in routine applications, finding good ways to parallelize popular algorithms has become increasingly important. In this paper, we present a parallelization scheme for Markov chain Monte…

Methodology · Statistics 2016-06-01 Guillaume W. Basse , Natesh S. Pillai , Aaron Smith

A parallel numerical simulation algorithm is presented for fractional-order systems involving Caputo-type derivatives, based on the Adams-Bashforth-Moulton (ABM) predictor-corrector scheme. The parallel algorithm is implemented using…

Mathematical Software · Computer Science 2017-10-04 Cosmin Bonchis , Eva Kaslik , Florin Rosu

Bayesian inference in hidden Markov models (HMMs) can be challenging due to the presence of multimodality in the likelihood function, and consequently in the joint posterior distribution, even after correcting for label switching. The…

Applications · Statistics 2026-05-01 Marco A. Gallegos-Herrada , Vianey Leos-Barajas , Jeffrey S. Rosenthal

Scripts have been proposed to model the stereotypical event sequences found in narratives. They can be applied to make a variety of inferences including filling gaps in the narratives and resolving ambiguous references. This paper proposes…

Computation and Language · Computer Science 2018-09-12 J. Walker Orr , Prasad Tadepalli , Janardhan Rao Doppa , Xiaoli Fern , Thomas G. Dietterich

This paper introduces a computational framework to incorporate flexible regularization techniques in ensemble Kalman methods for nonlinear inverse problems. The proposed methodology approximates the maximum a posteriori (MAP) estimate of a…

Computation · Statistics 2022-05-20 Hwanwoo Kim , Daniel Sanz-Alonso , Alexander Strang

We show that maximum entropy (maxent) models can be modeled with certain kinds of HMMs, allowing us to construct maxent models with hidden variables, hidden state sequences, or other characteristics. The models can be trained using the…

Artificial Intelligence · Computer Science 2013-01-07 Joshua Goodman

We introduce a framework for inference in general state-space hidden Markov models (HMMs) under likelihood misspecification. In particular, we leverage the loss-theoretic perspective of Generalized Bayesian Inference (GBI) to define…

Methodology · Statistics 2020-10-22 Ayman Boustati , Ömer Deniz Akyildiz , Theodoros Damoulas , Adam M. Johansen

We present a general framework for accelerating a large class of widely used Markov chain Monte Carlo (MCMC) algorithms. Our approach exploits fast, iterative approximations to the target density to speculatively evaluate many potential…

Machine Learning · Statistics 2014-03-31 Elaine Angelino , Eddie Kohler , Amos Waterland , Margo Seltzer , Ryan P. Adams

The parallel linear equations solver capable of effectively using 1000+ processors becomes the bottleneck of large-scale implicit engineering simulations. In this paper, we present a new hierarchical parallel master-slave-structural…

Computational Physics · Physics 2015-06-11 Ran Xu , Bin Liu , Yuan Dong

We propose a parallel adaptive constraint-tightening approach to solve a linear model predictive control problem for discrete-time systems, based on inexact numerical optimization algorithms and operator splitting methods. The underlying…

Optimization and Control · Mathematics 2015-03-24 Laura Ferranti , Tamas Keviczky