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Quantum computers promise scalable treatments of electronic structure, yet applying variational quantum eigensolvers (VQE) on realistic drug-like molecules remains constrained by the performance limitations of near-term quantum hardwares. A…

Chemical Physics · Physics 2025-12-23 Zhi Yin , Xiaoran Li , Zhupeng Han , Shengyu Zhang , Xin Li , Zhihong Zhang , Runqing Zhang , Anbang Wang , Xiaojin Zhang

Quantum chemistry provides key applications for near-term quantum computing, but these are greatly complicated by the presence of noise. In this work we present an efficient ansatz for the computation of two-electron atoms and molecules…

Quantum Physics · Physics 2020-04-23 Scott E. Smart , David A. Mazziotti

Due to numerous limitations including restrictive qubit topologies, short coherence times and prohibitively high noise floors, few quantum chemistry experiments performed on existing noisy intermediate-scale quantum hardware have achieved…

Quantum Physics · Physics 2023-10-20 Tim Weaving , Alexis Ralli , William M. Kirby , Peter J. Love , Sauro Succi , Peter V. Coveney

The method of increments and frozen natural orbital (MI-FNO) framework is introduced to help expedite the application of noisy, intermediate-scale quantum~(NISQ) devices for quantum chemistry simulations. The MI-FNO framework provides a…

Before the availability of large scale fault-tolerant quantum devices, one has to find ways to make the most of current noisy intermediate-scale quantum devices. One possibility is to seek smaller repetitive hybrid quantum-classical tasks…

Quantum Physics · Physics 2023-04-12 Teiko Heinosaari , Daniel Reitzner , Alessandro Toigo

Quantum phase estimation (QPE) is one of the core algorithms for quantum computing. It has been extensively studied and applied in a variety of quantum applications such as the Shor's factoring algorithm, quantum sampling algorithms and the…

Noise dominates every aspect of near-term quantum computers, rendering it exceedingly difficult to carry out even small computations. In this paper we are concerned with the modelling of noise in Noisy Intermediate-Scale Quantum (NISQ)…

Quantum Physics · Physics 2021-12-20 Konstantinos Georgopoulos , Clive Emary , Paolo Zuliani

Quantum sensing exploits non-classical effects to overcome limitations of classical sensors, with applications ranging from gravitational-wave detection to nanoscale imaging. However, practical quantum sensors built on noisy…

Quantum Physics · Physics 2025-05-30 Ivana Nikoloska , Hamdi Joudeh , Ruud van Sloun , Osvaldo Simeone

One of the requirements imposed on the realistic quantum computers is to provide computation results which can be repeated and reproduced. In the situation when one needs to repeat the quantum computation procedure several times, it is…

Quantum Physics · Physics 2022-10-05 Akash Kundu , Jarosław Adam Miszczak

Conventional computers have evolved to device components that demonstrate failure rates of 1e-17 or less, while current quantum computing devices typically exhibit error rates of 1e-2 or greater. This raises concerns about the reliability…

Quantum Physics · Physics 2022-11-02 Samudra Dasgupta , Travis S. Humble

We outline a proposal to test quantum mechanics in the high-complexity regime using noisy intermediate-scale quantum (NISQ) devices. The procedure involves simulating a non-Clifford random circuit, followed by its inverse, and then checking…

Quantum Physics · Physics 2022-08-26 Kevin Slagle

Quantum computers have the potential to help solve a range of physics and chemistry problems, but noise in quantum hardware currently limits our ability to obtain accurate results from the execution of quantum-simulation algorithms. Various…

Quantum Physics · Physics 2022-01-13 Eliott Rosenberg , Paul Ginsparg , Peter L. McMahon

Quantum reservoir computing algorithms recently emerged as a standout approach in the development of successful methods for the NISQ era, because of its superb performance and compatibility with current quantum devices. By harnessing the…

A practical fault-tolerant quantum computer is worth looking forward to as it provides applications that outperform their known classical counterparts. However, millions of interacting qubits with stringent criteria are required, which is…

Quantum Physics · Physics 2021-05-31 Keren Li

Determining the exponentially scaled ground state wavefunction and the associated molecular properties remains one of the central challenges in quantum chemistry. Hybrid quantum-classical algorithms implemented on quantum computers offer a…

Quantum Physics · Physics 2026-04-22 Dibyendu Mondal , Ashish Kumar Patra , Rahul Maitra

The advent of cloud quantum computing has led to the rapid development of quantum algorithms. In particular, it is necessary to study variational quantum-classical hybrid algorithms, which are executable on noisy intermediate-scale quantum…

Quantum Physics · Physics 2020-07-02 Ikko Hamamura , Takashi Imamichi

Quantum computers have the potential to simulate chemical systems beyond the capability of classical computers. Recent developments in hybrid quantum-classical approaches enable the determinations of the ground or low energy states of…

Quantum Physics · Physics 2021-12-06 Chee-Kong Lee , Jonathan Wei Zhong Lau , Liang Shi , Leong Chuan Kwek

Quantum systems are inherently open and susceptible to environmental noise, which can have both detrimental and beneficial effects on their dynamics. This phenomenon has been observed in bio-molecular systems, where noise enables novel…

Molecular simulations are widely regarded as leading candidates to demonstrate quantum advantage--defined as the point at which quantum methods surpass classical approaches in either accuracy or scale. Yet the qubit counts and error rates…

The main challenge of quantum computing on its way to scalability is the erroneous behaviour of current devices. Understanding and predicting their impact on computations is essential to counteract these errors with methods such as quantum…

Quantum Physics · Physics 2023-06-16 Tom Weber , Kerstin Borras , Karl Jansen , Dirk Krücker , Matthias Riebisch