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Attenuation compensation (AC), while being beneficial for visual-interpretation tasks in myocardial perfusion imaging (MPI) by SPECT, typically requires the availability of a separate X-ray CT component, leading to additional radiation…

Attenuation compensation (AC) is beneficial for visual interpretation tasks in single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI). However, traditional AC methods require the availability of a transmission…

Medical Physics · Physics 2023-03-21 Zitong Yu , Md Ashequr Rahman , Craig K. Abbey , Barry A. Siegel , Abhinav K. Jha

Reliable attenuation and scatter compensation (ASC) is a prerequisite for quantification and beneficial for visual interpretation tasks in SPECT. In this paper, we develop a reconstruction method that uses the entire SPECT emission data,…

Medical Physics · Physics 2020-03-02 Md Ashequr Rahman , Richard Laforest , Abhinav K. Jha

Attenuation artifacts remain a significant challenge in cardiac Myocardial Perfusion Imaging (MPI) using Single-Photon Emission Computed Tomography (SPECT), often compromising diagnostic accuracy and reducing clinical interpretability.…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Trung Kien Pham , Hoang Minh Vu , Anh Duc Chu , Dac Thai Nguyen , Trung Thanh Nguyen , Thao Nguyen Truong , Mai Hong Son , Thanh Trung Nguyen , Phi Le Nguyen

Quantitative measures of dopamine transporter (DaT) uptake in caudate, putamen, and globus pallidus derived from DaT-single-photon emission computed tomography (SPECT) images are being investigated as biomarkers to diagnose, assess disease…

Recent developments in artificial intelligence technology have enabled new developments that can improve attenuation and scatter correction in PET and SPECT. These technologies will enable the use of accurate and quantitative imaging…

Medical Physics · Physics 2021-08-30 Alan B. McMillan , Tyler J. Bradshaw

Attenuation and scatter correction (AC) is crucial for quantitative Positron Emission Tomography (PET) imaging. Recently, direct application of AC in the image domain using deep learning approaches has been proposed for the hybrid PET/MR…

Medical Physics · Physics 2022-06-30 Reza Jahangir , Alireza Kamali-Asl , Hossein Arabi

The potential to perform attenuation and scatter compensation (ASC) in single-photon emission computed tomography (SPECT) imaging using only the SPECT emission data is highly significant. In this context, attenuation in SPECT is primarily…

Photon attenuation and scatter are the two main physical factors affecting the diagnostic quality of SPECT in its applications in brain imaging. In this work, we present a novel Bayesian Optimization approach for Attenuation Correction…

Medical Physics · Physics 2021-09-27 Loizos Koutsantonis , Ayman Makki , Tiago Carneiro , Emmanuel Kieffer , Pascal Bouvry

Objective: In this work, we set out to investigate the accuracy of direct attenuation correction (AC) in the image domain for the myocardial perfusion SPECT imaging (MPI-SPECT) using two residual (ResNet) and UNet deep convolutional neural…

The Compton camera is a promising alternative to the Anger camera for imaging gamma radiation, with the potential to significantly increase the sensitivity of SPECT. Two-dimensional Compton camera image reconstruction can be implemented by…

Numerical Analysis · Mathematics 2016-09-13 Markus Haltmeier , Sunghwan Moon , Daniela Schiefeneder

Positron Emission Tomography (PET) imaging requires accurate attenuation correction (AC) to account for photon loss due to tissue density variations. In PET/MR systems, computed tomography (CT), which offers a straightforward estimation of…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Weijie Chen , James Wang , Alan McMillan

Attenuation correction (AC) is essential for the generation of artifact-free and quantitatively accurate positron emission tomography (PET) images. However, AC of PET faces challenges including inter-scan motion and erroneous transformation…

Image and Video Processing · Electrical Eng. & Systems 2023-10-04 Yu Guan , Bohui Shen , Xinchong Shi , Xiangsong Zhang , Bingxuan Li , Qiegen Liu

SPECT (Single-photon Emission Computerized Tomography) and PET (Positron Emission Tomography) are essential medical imaging tools, for which the sampling angle number, scan time should be chosen carefully to compromise between image quality…

Medical Physics · Physics 2015-06-16 Xiaolin Zhou , Minkai Yun , Xuexiang Cao , Shuangquan Liu , Lu Wang , Xianchao Huang , Long Wei

Single-photon avalanche diodes (SPADs) have emerged as a promising candidate for optical wireless communication (OWC) owing to their ultra-high sensitivity and singlephoton detection capability. However, under strong background radiation or…

Signal Processing · Electrical Eng. & Systems 2026-05-28 Chen Wang , Zhiyong Xu , Jingyuan Wang , Jianhua Li , Weifeng Mou , Huatao Zhu

Computed tomography (CT) reconstruction plays a crucial role in industrial nondestructive testing and medical diagnosis. Sparse view CT reconstruction aims to reconstruct high-quality CT images while only using a small number of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-12 Wangduo Xie , Richard Schoonhoven , Tristan van Leeuwen , Matthew B. Blaschko

A recently proposed scatter-window and deep learning-based attenuation compensation (AC) method for myocardial perfusion imaging (MPI) by single-photon emission computed tomography (SPECT), namely CTLESS, demonstrated promising performance…

Medical Physics · Physics 2025-03-24 Zitong Yu , Nu Ri Choi , Zezhang Yang , Nancy A. Obuchowski , Barry A. Siegel , Abhinav K. Jha

Recently, spectral CT has been drawing a lot of attention in a variety of clinical applications primarily due to its capability of providing quantitative information about material properties. The quantitative integrity of the reconstructed…

Medical Physics · Physics 2018-01-12 Shiyu Xu , Peter Prinsen , Jens Wiegert , Ravindra Manjeshwar

Single Photon Emission Computed Tomography (SPECT) is one of the nuclear medicine imaging modalities used for functional analysis of animal and human organs. Gamma rays emitted from the scanned body are filtered with collimators and…

Image and Video Processing · Electrical Eng. & Systems 2020-12-15 Manu Francis , Muhammed Tarek , Mark Pickering , Murat Tahtali

Myocardial perfusion imaging (MPI) with single-photon emission computed tomography (SPECT) is a widely used and cost-effective diagnostic tool for coronary artery disease. However, the lengthy scanning time in this imaging procedure can…

Computer Vision and Pattern Recognition · Computer Science 2025-04-24 Zezhang Yang , Zitong Yu , Nuri Choi , Abhinav K. Jha
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