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Convolutional Neural Networks (CNNs) have shown remarkable progress in medical image segmentation. However, lesion segmentation remains a challenge to state-of-the-art CNN-based algorithms due to the variance in scales and shapes. On the…

Convolutional Neural Network (CNN)-based machine learning systems have made breakthroughs in feature extraction and image recognition tasks in two dimensions (2D). Although there is significant ongoing work to apply CNN technology to…

Despite impressive performance on numerous visual tasks, Convolutional Neural Networks (CNNs) --- unlike brains --- are often highly sensitive to small perturbations of their input, e.g. adversarial noise leading to erroneous decisions. We…

Early and accurate detection through Pap smear analysis is critical to improving patient outcomes and reducing mortality of Cervical cancer. State-of-the-art (SOTA) Convolutional Neural Networks (CNNs) require substantial computational…

Convolutional Neural Networks (CNNs) are known to be significantly over-parametrized, and difficult to interpret, train and adapt. In this paper, we introduce a structural regularization across convolutional kernels in a CNN. In our…

Lesion segmentation in medical imaging serves as an effective tool for assessing tumor sizes and monitoring changes in growth. However, not only is manual lesion segmentation time-consuming, but it is also expensive and requires expert…

Weakly supervised object localization (WSOL) strives to learn to localize objects with only image-level supervision. Due to the local receptive fields generated by convolution operations, previous CNN-based methods suffer from partial…

Weakly supervised segmentation requires assigning a label to every pixel based on training instances with partial annotations such as image-level tags, object bounding boxes, labeled points and scribbles. This task is challenging, as coarse…

The detailed images produced by Magnetic Resonance Imaging (MRI) provide life-critical information for the diagnosis and treatment of prostate cancer. To provide standardized acquisition, interpretation and usage of the complex MRI images,…

Localization of chest pathologies in chest X-ray images is a challenging task because of their varying sizes and appearances. We propose a novel weakly supervised method to localize chest pathologies using class aware deep multiscale…

Single cell segmentation is critical and challenging in live cell imaging data analysis. Traditional image processing methods and tools require time-consuming and labor-intensive efforts of manually fine-tuning parameters. Slight variations…

Convolutional Neural Networks (CNNs) have been used for automated detection of prostate cancer where Area Under Receiver Operating Characteristic (ROC) curve (AUC) is usually used as the performance metric. Given that AUC is not…

Medical image registration is one of the key processing steps for biomedical image analysis such as cancer diagnosis. Recently, deep learning based supervised and unsupervised image registration methods have been extensively studied due to…

Recently, significant improvement has been made on semantic object segmentation due to the development of deep convolutional neural networks (DCNNs). Training such a DCNN usually relies on a large number of images with pixel-level…

Despite the remarkable progress, weakly supervised segmentation approaches are still inferior to their fully supervised counterparts. We obverse the performance gap mainly comes from their limitation on learning to produce high-quality…

Weakly supervised learning of object detection is an important problem in image understanding that still does not have a satisfactory solution. In this paper, we address this problem by exploiting the power of deep convolutional neural…

Deep learning has shown remarkable progress in medical image semantic segmentation, yet its success heavily depends on large-scale expert annotations and consistent data distributions. In practice, annotations are scarce, and images are…

Polyp segmentation is a crucial step towards computer-aided diagnosis of colorectal cancer. However, most of the polyp segmentation methods require pixel-wise annotated datasets. Annotated datasets are tedious and time-consuming to produce,…

Convolutional neural networks (CNNs) are the cutting edge model for supervised machine learning in computer vision. In recent years CNNs have outperformed traditional approaches in many computer vision tasks such as object detection, image…

Automatic pancreas segmentation in radiology images, eg., computed tomography (CT) and magnetic resonance imaging (MRI), is frequently required by computer-aided screening, diagnosis, and quantitative assessment. Yet pancreas is a…