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Single-Photon Emission Computed Tomography (SPECT) is widely applied for the diagnosis of coronary artery diseases. Low-dose (LD) SPECT aims to minimize radiation exposure but leads to increased image noise. Limited-view (LV) SPECT, such as…

Image and Video Processing · Electrical Eng. & Systems 2024-01-25 Xiongchao Chen , Bo Zhou , Xueqi Guo , Huidong Xie , Qiong Liu , James S. Duncan , Albert J. Sinusas , Chi Liu

Cardiovascular disease (CVD) is the leading cause of death worldwide, and myocardial perfusion imaging using SPECT has been widely used in the diagnosis of CVDs. The GE 530/570c dedicated cardiac SPECT scanners adopt a stationary geometry…

Image and Video Processing · Electrical Eng. & Systems 2023-07-25 Huidong Xie , Bo Zhou , Xiongchao Chen , Xueqi Guo , Stephanie Thorn , Yi-Hwa Liu , Ge Wang , Albert Sinusas , Chi Liu

Objectives: We propose a deep learning (DL) multi-task learning framework using convolutional neural network (CNN) for a direct conversion of single-energy CT (SECT) to three different parametric maps of dual-energy CT (DECT):…

Medical Physics · Physics 2023-09-28 Sangwook Kim , Jimin Lee , Jungye Kim , Bitbyeol Kim , Chang Heon Choi , Seongmoon Jung

A recently proposed scatter-window and deep learning-based attenuation compensation (AC) method for myocardial perfusion imaging (MPI) by single-photon emission computed tomography (SPECT), namely CTLESS, demonstrated promising performance…

Medical Physics · Physics 2025-03-24 Zitong Yu , Nu Ri Choi , Zezhang Yang , Nancy A. Obuchowski , Barry A. Siegel , Abhinav K. Jha

Single-photon emission computed tomography for myocardial perfusion imaging (MPI SPECT) is a widely used diagnostic tool for coronary artery disease. However, the procedure requires considerable scanning time, leading to patient discomfort…

Image and Video Processing · Electrical Eng. & Systems 2026-04-27 Zezhang Yang , Zitong Yu , Nuri Choi , Janice Tania , Wenxuan Xue , Barry A. Siegel , Abhinav K. Jha

Photoacoustic imaging (PAI) is a non-invasive imaging modality that detects the ultrasound signal generated from tissue with light excitation. Photoacoustic computed tomography (PACT) uses unfocused large-area light to illuminate the target…

Image and Video Processing · Electrical Eng. & Systems 2022-04-13 Hengrong Lan , Jiali Gong , Fei Gao

Dynamic computed tomography perfusion (CTP) imaging is a promising approach for acute ischemic stroke diagnosis and evaluation. Hemodynamic parametric maps of cerebral parenchyma are calculated from repeated CT scans of the first pass of…

Medical Physics · Physics 2020-05-21 Dufan Wu , Hui Ren , Quanzheng Li

One primary technical challenge in photoacoustic microscopy (PAM) is the necessary compromise between spatial resolution and imaging speed. In this study, we propose a novel application of deep learning principles to reconstruct…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Anthony DiSpirito , Daiwei Li , Tri Vu , Maomao Chen , Dong Zhang , Jianwen Luo , Roarke Horstmeyer , Junjie Yao

Myocardial perfusion imaging using single-photon emission computed tomography (SPECT), or myocardial perfusion SPECT (MPS) is a widely used clinical imaging modality for the diagnosis of coronary artery disease. Current clinical protocols…

Medical Physics · Physics 2024-03-27 Nu Ri Choi , Md Ashequr Rahman , Zitong Yu , Barry A. Siegel , Abhinav K. Jha

Purpose: To develop and evaluate the accuracy of a multi-view deep learning approach to the analysis of high-resolution synthetic mammograms from digital breast tomosynthesis screening cases, and to assess the effect on accuracy of image…

Image and Video Processing · Electrical Eng. & Systems 2020-09-29 Saeed Seyyedi , Margaret J. Wong , Debra M. Ikeda , Curtis P. Langlotz

Positron Emission Tomography (PET) imaging requires accurate attenuation correction (AC) to account for photon loss due to tissue density variations. In PET/MR systems, computed tomography (CT), which offers a straightforward estimation of…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Weijie Chen , James Wang , Alan McMillan

The ability to synthesise Computed Tomography images - commonly known as pseudo CT, or pCT - from MRI input data is commonly assessed using an intensity-wise similarity, such as an L2-norm between the ground truth CT and the pCT. However,…

Image and Video Processing · Electrical Eng. & Systems 2020-04-15 Kerstin Kläser , Thomas Varsavsky , Pawel Markiewicz , Tom Vercauteren , David Atkinson , Kris Thielemans , Brian Hutton , M Jorge Cardoso , Sebastien Ourselin

Increasing use of CT in modern medical practice has raised concerns over associated radiation dose. Reduction of radiation dose associated with CT can increase noise and artifacts, which can adversely affect diagnostic confidence. Denoising…

Computer Vision and Pattern Recognition · Computer Science 2017-02-24 Qingsong Yang , Pingkun Yan , Mannudeep K. Kalra , Ge Wang

Accurate segmentation of the left ventricle myocardium in cardiac CT angiography (CCTA) is essential for e.g. the assessment of myocardial perfusion. Automatic deep learning methods for segmentation in CCTA might suffer from differences in…

Computer Vision and Pattern Recognition · Computer Science 2019-01-29 Steffen Bruns , Jelmer M. Wolterink , Robbert W. van Hamersvelt , Majd Zreik , Tim Leiner , Ivana Išgum

Positron Emission Tomography (PET) is a functional imaging modality widely used in neuroscience studies. To obtain meaningful quantitative results from PET images, attenuation correction is necessary during image reconstruction. For PET/MR…

Medical Physics · Physics 2018-08-01 Kuang Gong , Jaewon Yang , Kyungsang Kim , Georges El Fakhri , Youngho Seo , Quanzheng Li

Purpose: Optical Coherence Tomography Angiography (OCT-A) permits visualization of the changes to the retinal circulation due to diabetic retinopathy (DR), a microvascular complication of diabetes. We demonstrate accurate segmentation of…

Image and Video Processing · Electrical Eng. & Systems 2021-01-13 Julian Lo , Morgan Heisler , Vinicius Vanzan , Sonja Karst , Ivana Zadro Matovinovic , Sven Loncaric , Eduardo V. Navajas , Mirza Faisal Beg , Marinko V. Sarunic

Self-supervised pre-training of deep learning models with contrastive learning is a widely used technique in image analysis. Current findings indicate a strong potential for contrastive pre-training on medical images. However, further…

Image and Video Processing · Electrical Eng. & Systems 2024-10-21 Daniel Wolf , Tristan Payer , Catharina Silvia Lisson , Christoph Gerhard Lisson , Meinrad Beer , Michael Götz , Timo Ropinski

Chromatic dispersion is a common problem to degrade the system resolution in optical coherence tomography (OCT). This study is to develop a deep learning network for automated dispersion compensation (ADC-Net) in OCT. The ADC-Net is based…

Pathological alterations in the human vascular system underlie many chronic diseases, such as atherosclerosis and aneurysms. However, manually analyzing diagnostic images of the vascular system, such as computed tomographic angiograms…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Alireza Bagheri Rajeoni , Breanna Pederson , Ali Firooz , Hamed Abdollahi , Andrew K. Smith , Daniel G. Clair , Susan M. Lessner , Homayoun Valafar

Recent developments in artificial intelligence technology have enabled new developments that can improve attenuation and scatter correction in PET and SPECT. These technologies will enable the use of accurate and quantitative imaging…

Medical Physics · Physics 2021-08-30 Alan B. McMillan , Tyler J. Bradshaw