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Related papers: Lowest-cost virus suppression

200 papers

Models for control of epidemics on local, global and small-world networks are considered, with only partial information accessible about the status of individuals and their connections. The main goal of an effective control measure is to…

Physics and Society · Physics 2007-05-23 A. Kleczkowski , B. Dybiec , C. A. Gilligan

In an emerging pandemic, policymakers need to make important decisions with limited information, for example choosing between a mitigation, suppression or elimination strategy. These strategies may require trade-offs to be made between the…

Populations and Evolution · Quantitative Biology 2026-05-27 M J Plank , M Sushames , T Fisher-Taylor , A Afshari , R N Thompson , A Hurford , S C Hendy

An epidemic carries human and fiscal costs. In the case of imported pandemics, the first-best solution is to restrict national borders to identify and isolate infected individuals. However, when that opportunity is not fully seized and…

Populations and Evolution · Quantitative Biology 2022-03-31 Mayteé Cruz-Aponte , José Caraballo-Cueto

We investigate the containment of epidemic spreading in networks from a normative point of view. We consider a susceptible/infected model in which agents can invest in order to reduce the contagiousness of network links. In this setting, we…

Theoretical Economics · Economics 2020-07-16 Geraldine Bouveret , Antoine Mandel

We analyse 'stop-and-go' containment policies that produce infection cycles as periods of tight lockdowns are followed by periods of falling infection rates. The subsequent relaxation of containment measures allows cases to increase again…

Theoretical Economics · Economics 2021-11-22 Claudius Gros , Daniel Gros

The design of an efficient curing policy, able to stem an epidemic process at an affordable cost, has to account for the structure of the population contact network supporting the contagious process. Thus, we tackle the problem of…

Optimization and Control · Mathematics 2017-12-04 Stefania Ottaviano , Francesco De Pellegrini , Stefano Bonaccorsi , Piet Van Mieghem

As a common strategy of contagious disease containment, lockdowns will inevitably weaken the economy. The ongoing COVID-19 pandemic underscores the trade-off arising from public health and economic cost. An optimal lockdown policy to…

Optimization and Control · Mathematics 2022-01-26 Qianqian Ma , Yang-Yu Liu , Alex Olshevsky

When effective medical treatment and vaccination are not available, non-pharmaceutical interventions such as social distancing, home quarantine and far-reaching shutdown of public life are the only available strategies to prevent the spread…

Populations and Evolution · Quantitative Biology 2020-08-19 Markus Kantner , Thomas Koprucki

In this research, we develop a framework to analyze the interaction between the economy and the Covid-19 pandemic using an extension of SIR epidemic model. At the outset, we assume there are two health related investments including general…

Optimization and Control · Mathematics 2022-02-14 Zachariah Sinkala , Vajira Manathunga , Bichaka Fayissa

The recent COVID-19 pandemic highlighted the need of non-pharmaceutical interventions in the first stages of a pandemic. Among these, lockdown policies proved unavoidable yet extremely costly from an economic perspective. To better…

Optimization and Control · Mathematics 2021-12-14 Leonardo Cianfanelli , Francesca Parise , Daron Acemoglu , Giacomo Como , Asuman Ozdaglar

After the first lockdown in response to the COVID-19 outbreak, many countries faced difficulties in balancing infection control with economics. Due to limited prior knowledge, economists began researching this issue using cost-benefit…

Populations and Evolution · Quantitative Biology 2021-10-19 Tsuyoshi Hondou

The rapid spread of the Coronavirus (COVID-19) confronts policy makers with the problem of measuring the effectiveness of containment strategies, balancing public health considerations with the economic costs of social distancing measures.…

Physics and Society · Physics 2021-04-02 Claudius Gros , Roser Valenti , Lukas Schneider , Kilian Valenti , Daniel Gros

Efficient testing and vaccination protocols are critical aspects of epidemic management. To study the optimal allocation of limited testing and vaccination resources in a heterogeneous contact network of interacting susceptible, recovered,…

Populations and Evolution · Quantitative Biology 2026-05-12 Mingtao Xia , Lucas Böttcher , Tom Chou

Given multiple new COVID-19 variants are continuously emerging, non-pharmaceutical interventions are still primary control strategies to curb the further spread of coronavirus. However, implementing strict interventions over extended…

Populations and Evolution · Quantitative Biology 2022-03-01 Xiao Zhou , Xiaohu Zhang , Paolo Santi , Carlo Ratti

We present a local spread model of disease transmission on a regular network and compare different control options ranging from treating the whole population to local control in a well-defined neighborhood of an infectious individual.…

Biological Physics · Physics 2015-05-30 Katarzyna Oles , Ewa Gudowska-Nowak , Adam Kleczkowski

During the COVID-19 pandemic, case isolation emerged as a key non-pharmaceutical intervention in pandemic response. Its effectiveness hinges on the timing of isolation, which is often dictated by the onset of contagiousness. While…

Populations and Evolution · Quantitative Biology 2025-02-03 Jiahao Diao , Rebecca H. Chisholm , Nicholas Geard , James M. McCaw

National responses to the Covid-19 pandemic varied markedly across countries, from business-as-usual to complete shutdowns. Policies aimed at disrupting the viral transmission cycle and preventing the healthcare system from being…

Populations and Evolution · Quantitative Biology 2021-10-27 Arash Saeidpour , Pejman Rohani

We consider the problem of controlling an SIR-model epidemic by temporarily reducing the rate of contact within a population. The control takes the form of a multiplicative reduction in the contact rate of infectious individuals. The…

Optimization and Control · Mathematics 2021-06-29 David I. Ketcheson

During an infectious disease outbreak, policymakers must balance medical costs with social and economic burdens and seek interventions that minimize both. To support this decision-making process, we developed a framework that integrates…

Optimization and Control · Mathematics 2026-04-03 Jongmin Lee , Renier Mendoza , Victoria May P. Mendoza , Eunok Jung

This work introduces a novel epidemiological model that simultaneously considers multiple viral strains, reinfections due to waning immunity response over time and an optimal control formulation. This enables us to derive optimal mitigation…

Systems and Control · Electrical Eng. & Systems 2021-09-10 Edilson F. Arruda , Dayse H. Pastore , Clauda M. Dias , Shyam S. Das