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Accurately imputing traffic flow at unsensed locations is difficult: loop detectors provide precise but sparse measurements, speed from probe vehicles is widely available yet only weakly correlated with flow, and nearby links often exhibit…

Machine Learning · Computer Science 2025-12-23 Mohammadmahdi Rahimiasl , Ynte Vanderhoydonc , Siegfried Mercelis

Heterogeneous treatment effects (HTEs) are commonly identified during randomized controlled trials (RCTs). Identifying subgroups of patients with similar treatment effects is of high interest in clinical research to advance precision…

Machine Learning · Computer Science 2022-12-06 Peniel N. Argaw , Elizabeth Healey , Isaac S. Kohane

Drug-target interaction (DTI) prediction is crucial for drug development and repositioning. Methods using heterogeneous graph neural networks (HGNNs) for DTI prediction have become a promising approach, with attention-based models often…

Biomolecules · Quantitative Biology 2024-11-05 Junwei Hu , Michael Bewong , Selasi Kwashie , Wen Zhang , Vincent M. Nofong , Guangsheng Wu , Zaiwen Feng

In medicine, treatments often influence multiple, interdependent outcomes, such as primary endpoints, complications, adverse events, or other secondary endpoints. Hence, to make optimal treatment decisions, clinicians are interested in…

Machine Learning · Computer Science 2025-06-03 Yuchen Ma , Jonas Schweisthal , Hengrui Zhang , Stefan Feuerriegel

Deploying deep neural networks for risk-sensitive tasks necessitates an uncertainty estimation mechanism. This paper introduces hierarchical selective classification, extending selective classification to a hierarchical setting. Our…

Machine Learning · Computer Science 2025-01-07 Shani Goren , Ido Galil , Ran El-Yaniv

Proteins perform their functions usually by interacting with other proteins. Predicting which proteins interact is a fundamental problem. Experimental methods are slow, expensive, and have a high rate of error. Many computational methods…

Biomolecules · Quantitative Biology 2017-05-22 Yiwei Li , Lucian Ilie

Link and sign prediction in complex networks bring great help to decision-making and recommender systems, such as in predicting potential relationships or relative status levels. Many previous studies focused on designing the special…

Physics and Society · Physics 2021-08-04 Chuang Liu , Shimin Yu , Ying Huang , Zi-Ke Zhang

Modern high-dimensional point process data, especially those from neuroscience experiments, often involve observations from multiple conditions and/or experiments. Networks of interactions corresponding to these conditions are expected to…

Methodology · Statistics 2021-09-27 Xu Wang , Ali Shojaie

Outcome prediction from clinical text can prevent doctors from overlooking possible risks and help hospitals to plan capacities. We simulate patients at admission time, when decision support can be especially valuable, and contribute a…

Computation and Language · Computer Science 2021-02-09 Betty van Aken , Jens-Michalis Papaioannou , Manuel Mayrdorfer , Klemens Budde , Felix A. Gers , Alexander Löser

Estimating heterogeneous treatment effects is an important problem across many domains. In order to accurately estimate such treatment effects, one typically relies on data from observational studies or randomized experiments. Currently,…

Machine Learning · Statistics 2022-02-28 Tobias Hatt , Jeroen Berrevoets , Alicia Curth , Stefan Feuerriegel , Mihaela van der Schaar

Network embedding is an effective way to solve the network analytics problems such as node classification, link prediction, etc. It represents network elements using low dimensional vectors such that the graph structural information and…

Social and Information Networks · Computer Science 2019-09-04 Yucheng Lin , Xiaoqing Yang , Zang Li , Jieping Ye

Click-Through Rate (CTR) prediction, which aims to estimate the probability that a user will click an item, is an essential component of online advertising. Existing methods mainly attempt to mine user interests from users' historical…

Information Retrieval · Computer Science 2022-07-25 Erxue Min , Yu Rong , Tingyang Xu , Yatao Bian , Peilin Zhao , Junzhou Huang , Da Luo , Kangyi Lin , Sophia Ananiadou

The link prediction task aims to predict missing entities or relations in the knowledge graph and is essential for the downstream application. Existing well-known models deal with this task by mainly focusing on representing knowledge graph…

Computation and Language · Computer Science 2023-03-29 Jin Liu , Jianye Chen , Chongfeng Fan , Fengyu Zhou

Medicinal synergy prediction is a powerful tool in drug discovery and development that harnesses the principles of combination therapy to enhance therapeutic outcomes by improving efficacy, reducing toxicity, and preventing drug resistance.…

Computational Engineering, Finance, and Science · Computer Science 2024-11-26 Jiawei Wu , Jun Wen , Mingyuan Yan , Anqi Dong , Shuai Gao , Ren Wang , Can Chen

Matching is an appealing way to design observational studies because it mimics the data structure produced by stratified randomized trials, pairing treated individuals with similar controls. After matching, inference is often conducted…

Methodology · Statistics 2024-03-05 Samuel D. Pimentel , Ruoqi Yu

Motivation: Identifying drug-target interactions (DTIs) is a key step in drug repositioning. In recent years, the accumulation of a large number of genomics and pharmacology data has formed mass drug and target related heterogeneous…

Machine Learning · Computer Science 2022-10-19 Hongzhun Wang , Feng Huang , Wen Zhang

Heterogeneous information networks(HINs) become popular in recent years for its strong capability of modelling objects with abundant information using explicit network structure. Network embedding has been proved as an effective method to…

Machine Learning · Computer Science 2021-04-12 Xinyi Zhang , Lihui Chen

Effectively medication recommendation with complex multimorbidity conditions is a critical task in healthcare. Most existing works predicted medications based on longitudinal records, which assumed the information transmitted patterns of…

Machine Learning · Computer Science 2023-09-13 Sicen Liu , Xiaolong Wang , JIngcheng Du , Yongshuai Hou , Xianbing Zhao , Hui Xu , Hui Wang , Yang Xiang , Buzhou Tang

Heterogeneous information networks (HINs) are ubiquitous in real-world applications. In the meantime, network embedding has emerged as a convenient tool to mine and learn from networked data. As a result, it is of interest to develop HIN…

Social and Information Networks · Computer Science 2018-07-11 Yu Shi , Qi Zhu , Fang Guo , Chao Zhang , Jiawei Han

Heterogeneous information network (HIN) embedding aims to embed multiple types of nodes into a low-dimensional space. Although most existing HIN embedding methods consider heterogeneous relations in HINs, they usually employ one single…

Social and Information Networks · Computer Science 2019-05-21 Yuanfu Lu , Chuan Shi , Linmei Hu , Zhiyuan Liu
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