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Reliable attenuation and scatter compensation (ASC) is a prerequisite for quantification and beneficial for visual interpretation tasks in SPECT. In this paper, we develop a reconstruction method that uses the entire SPECT emission data,…

Medical Physics · Physics 2020-03-02 Md Ashequr Rahman , Richard Laforest , Abhinav K. Jha

SPECT provides a mechanism to perform absorbed-dose quantification tasks for $\alpha$-particle radiopharmaceutical therapies ($\alpha$-RPTs). However, quantitative SPECT for $\alpha$-RPT is challenging due to the low number of detected…

SPECT can enable the quantification of activity uptake in lesions and at-risk organs in {\alpha}-particle-emitting radiopharmaceutical therapies ({\alpha}-RPTs). But this quantification is challenged by the low photon counts, complicated…

Medical Physics · Physics 2024-03-27 Zekun Li , Nadia Benabdallah , Daniel L. J. Thorek , Abhinav K. Jha

We introduce the spiked mixture model (SMM) to address the problem of estimating a set of signals from many randomly scaled and noisy observations. Subsequently, we design a novel expectation-maximization (EM) algorithm to recover all…

Machine Learning · Statistics 2026-01-26 Paul-Louis Delacour , Sander Wahls , Jeffrey M. Spraggins , Lukasz Migas , Raf Van de Plas

Single-photon emission computed tomography (SPECT) provides a mechanism to estimate regional isotope uptake in lesions and at-risk organs after administration of {\alpha}-particle-emitting radiopharmaceutical therapies ({\alpha}-RPTs).…

The past decade has seen an increased interest in human activity recognition based on sensor data. Most often, the sensor data come unannotated, creating the need for fast labelling methods. For assessing the quality of the labelling, an…

Computer Vision and Pattern Recognition · Computer Science 2023-05-04 Michał Ciszewski , Jakob Söhl , Geurt Jongbloed

Recently it has been shown that precise dose control and an increase in the overall acquisition speed of atomic resolution scanning transmission electron microscope (STEM) images can be achieved by acquiring only a small fraction of the…

Photon attenuation and scatter are the two main physical factors affecting the diagnostic quality of SPECT in its applications in brain imaging. In this work, we present a novel Bayesian Optimization approach for Attenuation Correction…

Medical Physics · Physics 2021-09-27 Loizos Koutsantonis , Ayman Makki , Tiago Carneiro , Emmanuel Kieffer , Pascal Bouvry

Myocardial perfusion imaging using single-photon emission computed tomography (SPECT), or myocardial perfusion SPECT (MPS) is a widely used clinical imaging modality for the diagnosis of coronary artery disease. Current clinical protocols…

Medical Physics · Physics 2024-03-27 Nu Ri Choi , Md Ashequr Rahman , Zitong Yu , Barry A. Siegel , Abhinav K. Jha

SPECT (Single-photon Emission Computerized Tomography) and PET (Positron Emission Tomography) are essential medical imaging tools, for which the sampling angle number, scan time should be chosen carefully to compromise between image quality…

Medical Physics · Physics 2015-06-16 Xiaolin Zhou , Minkai Yun , Xuexiang Cao , Shuangquan Liu , Lu Wang , Xianchao Huang , Long Wei

Medical image foundation models have shown the ability to segment organs and tumors with minimal fine-tuning. These models are typically evaluated on task-specific in-distribution (ID) datasets. However, reliable performance on ID datasets…

Image and Video Processing · Electrical Eng. & Systems 2025-01-31 Aneesh Rangnekar , Nishant Nadkarni , Jue Jiang , Harini Veeraraghavan

In this work we explored the use of patient specific reinforced learning to generate 3D activity maps from two 2D planar images (anterior and posterior). The solution of this problem remains unachievable using conventional methodologies and…

Traditional supervised 3D medical image segmentation models need voxel-level annotations, which require huge human effort, time, and cost. Semi-supervised learning (SSL) addresses this limitation of supervised learning by facilitating…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Suruchi Kumari , Aryan Das , Swalpa Kumar Roy , Indu Joshi , Pravendra Singh

A growing body of work studies Blindspot Discovery Methods ("BDM"s): methods that use an image embedding to find semantically meaningful (i.e., united by a human-understandable concept) subsets of the data where an image classifier performs…

Machine Learning · Computer Science 2023-07-13 Gregory Plumb , Nari Johnson , Ángel Alexander Cabrera , Ameet Talwalkar

In the era of large language models (LLMs), weight-activation quantization helps fit models on edge device by reducing memory and compute bit-widths. However, three challenges persist for energy constrained hardware: (1) even after…

Machine Learning · Computer Science 2025-10-23 Chenyu Wang , Zhanglu Yan , Zhi Zhou , Xu Chen , Weng-Fai Wong

In this paper, we demonstrate that an inherent waveform pattern in the attention allocation of large language models (LLMs) significantly affects their performance in tasks demanding a high degree of context awareness, such as utilizing…

Computation and Language · Computer Science 2024-06-05 Yuhan Chen , Ang Lv , Ting-En Lin , Changyu Chen , Yuchuan Wu , Fei Huang , Yongbin Li , Rui Yan

In this paper, we presented an efficient algorithm to implement the regularization reconstruction of SPECT. Image reconstruction with priori assumptions is usually modeled as a constrained optimization problem. However, there is no…

Optimization and Control · Mathematics 2013-06-07 Shousheng Luo , Tie Zhou

Semantic segmentation is one of the core tasks in the field of computer vision, and its goal is to accurately classify each pixel in an image. The traditional Unet model achieves efficient feature extraction and fusion through an…

Computer Vision and Pattern Recognition · Computer Science 2025-02-07 Xuan Li , Quanchao Lu , Yankaiqi Li , Muqing Li , Yijiashun Qi

Aims. The purpose of this study is to create a multi-stage machine learning model to predict cardiac resynchronization therapy (CRT) response for heart failure (HF) patients. This model exploits uncertainty quantification to recommend…

This research aims to optimize intricate learning models by implementing quantization and bit-depth optimization techniques. The objective is to significantly cut time complexity while preserving model efficiency, thus addressing the…

Machine Learning · Computer Science 2025-11-18 Mitul Goswami , Romit Chatterjee
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