English
Related papers

Related papers: On Utility and Privacy in Synthetic Genomic Data

200 papers

Private synthetic data sharing is preferred as it keeps the distribution and nuances of original data compared to summary statistics. The state-of-the-art methods adopt a select-measure-generate paradigm, but measuring large domain…

Cryptography and Security · Computer Science 2023-10-11 Meifan Zhang , Dihang Deng , Lihua Yin

Machine learning practitioners frequently seek to leverage the most informative available data, without violating the data owner's privacy, when building predictive models. Differentially private data synthesis protects personal details…

Machine Learning · Computer Science 2020-11-12 Lucas Rosenblatt , Xiaoyan Liu , Samira Pouyanfar , Eduardo de Leon , Anuj Desai , Joshua Allen

As privacy regulations become more stringent and access to real-world data becomes increasingly constrained, synthetic data generation has emerged as a vital solution, especially for tabular datasets, which are central to domains like…

Machine Learning · Computer Science 2025-07-17 Raju Challagundla , Mohsen Dorodchi , Pu Wang , Minwoo Lee

As Deep Learning algorithms continue to evolve and become more sophisticated, they require massive datasets for model training and efficacy of models. Some of those data requirements can be met with the help of existing datasets within the…

Machine Learning · Statistics 2022-04-07 Monik Raj Behera , Sudhir Upadhyay , Suresh Shetty , Sudha Priyadarshini , Palka Patel , Ker Farn Lee

Synthetic Data is not new, but recent advances in Generative AI have raised interest in expanding the research toolbox, creating new opportunities and risks. This article provides a taxonomy of the full breadth of the Synthetic Data domain.…

Human-Computer Interaction · Computer Science 2024-08-29 Richard Timpone , Yongwei Yang

While location trajectories represent a valuable data source for analyses and location-based services, they can reveal sensitive information, such as political and religious preferences. Differentially private publication mechanisms have…

Cryptography and Security · Computer Science 2024-06-28 Erik Buchholz , Alsharif Abuadbba , Shuo Wang , Surya Nepal , Salil S. Kanhere

This paper explores the strategic use of modern synthetic data generation and advanced data perturbation techniques to enhance security, maintain analytical utility, and improve operational efficiency when managing large datasets, with a…

Cryptography and Security · Computer Science 2025-04-29 Anantha Sharma , Swetha Devabhaktuni , Eklove Mohan

Deep learning models have demonstrated superior performance in several application problems, such as image classification and speech processing. However, creating a deep learning model using health record data requires addressing certain…

Machine Learning · Computer Science 2021-12-14 Amirsina Torfi , Edward A. Fox , Chandan K. Reddy

The generation of privacy-preserving synthetic datasets is a promising avenue for overcoming data scarcity in medical AI research. Post-hoc privacy filtering techniques, designed to remove samples containing personally identifiable…

Machine Learning · Computer Science 2025-10-03 Adil Koeken , Alexander Ziller , Moritz Knolle , Daniel Rueckert

Financial regulators such as central banks collect vast amounts of data, but access to the resulting fine-grained banking microdata is severely restricted by banking secrecy laws. Recent developments have resulted in mechanisms that…

Computational Finance · Quantitative Finance 2024-10-31 Hugo E. Caceres , Ben Moews

Synthetic data generation is a promising technique to facilitate the use of sensitive data while mitigating the risk of privacy breaches. However, for synthetic data to be useful in downstream analysis tasks, it needs to be of sufficient…

Machine Learning · Statistics 2024-08-26 Thom Benjamin Volker , Peter-Paul de Wolf , Erik-Jan van Kesteren

Trajectory data is fundamental to modern urban intelligence, yet its sensitivity raises significant privacy concerns. Generative models such as Generative Adversarial Networks, Variational Autoencoders, and Diffusion Models have been…

Recent advances in synthetic data generation (SDG) have been hailed as a solution to the difficult problem of sharing sensitive data while protecting privacy. SDG aims to learn statistical properties of real data in order to generate…

Machine Learning · Computer Science 2024-05-10 Meenatchi Sundaram Muthu Selva Annamalai , Andrea Gadotti , Luc Rocher

Generative models trained with Differential Privacy (DP) can produce synthetic data while reducing privacy risks. However, navigating their privacy-utility tradeoffs makes finding the best models for specific settings/tasks challenging.…

Machine Learning · Computer Science 2024-08-30 Georgi Ganev , Kai Xu , Emiliano De Cristofaro

The synthetic data approach to data confidentiality has been actively researched on, and for the past decade or so, a good number of high quality work on developing innovative synthesizers, creating appropriate utility measures and risk…

Methodology · Statistics 2021-05-11 Jingchen Hu

Differential privacy (DP) data synthesizers support public release of sensitive information, offering theoretical guarantees for privacy but limited evidence of utility in practical settings. Utility is typically measured as the error on…

Polygenic risk scores and other genomic analyses require large individual-level genotype datasets, yet strict data access restrictions impede sharing. Synthetic genotype generation offers a privacy-preserving alternative, but most existing…

In this work, we develop a privacy-by-design generative model for synthesizing the activity diary of the travel population using state-of-art deep learning approaches. This proposed approach extends literature on population synthesis by…

Machine Learning · Computer Science 2021-01-01 Godwin Badu-Marfo , Bilal Farooq , Zachary Patterson

Sequential data is everywhere, and it can serve as a basis for research that will lead to improved processes. For example, road infrastructure can be improved by identifying bottlenecks in GPS data, or early diagnosis can be improved by…

Cryptography and Security · Computer Science 2020-02-25 Sigal Shaked , Lior Rokach

With the reduction of sequencing costs and the pervasiveness of computing devices, genomic data collection is continually growing. However, data collection is highly fragmented and the data is still siloed across different repositories.…

Cryptography and Security · Computer Science 2022-03-14 Leonard Dervishi , Xinyue Wang , Wentao Li , Anisa Halimi , Jaideep Vaidya , Xiaoqian Jiang , Erman Ayday