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Related papers: On Utility and Privacy in Synthetic Genomic Data

200 papers

Synthetic data is emerging as a cost-effective solution necessary to meet the increasing data demands of AI development, created either from existing knowledge or derived from real data. The traditional classification of synthetic data…

Machine Learning · Computer Science 2025-08-07 Vibeke Binz Vallevik , Serena Elizabeth Marshall , Aleksandar Babic , Jan Franz Nygaard

Preservation of private user data is of paramount importance for high Quality of Experience (QoE) and acceptability, particularly with services treating sensitive data, such as IT-based health services. Whereas anonymization techniques were…

Machine Learning · Computer Science 2024-03-04 Navid Ashrafi , Vera Schmitt , Robert P. Spang , Sebastian Möller , Jan-Niklas Voigt-Antons

Techniques to deliver privacy-preserving synthetic datasets take a sensitive dataset as input and produce a similar dataset as output while maintaining differential privacy. These approaches have the potential to improve data sharing and…

Databases · Computer Science 2018-08-24 Luke Rodriguez , Bill Howe

Synthetic health data have the potential to mitigate privacy concerns when sharing data to support biomedical research and the development of innovative healthcare applications. Modern approaches for data generation based on machine…

Machine Learning · Computer Science 2023-01-11 Chao Yan , Yao Yan , Zhiyu Wan , Ziqi Zhang , Larsson Omberg , Justin Guinney , Sean D. Mooney , Bradley A. Malin

Artificial intelligence and data access are already mainstream. One of the main challenges when designing an artificial intelligence or disclosing content from a database is preserving the privacy of individuals who participate in the…

Cryptography and Security · Computer Science 2023-12-13 Clément Pierquin , Bastien Zimmermann , Matthieu Boussard

The rapid growth in data availability has facilitated research and development, yet not all industries have benefited equally due to legal and privacy constraints. The healthcare sector faces significant challenges in utilizing patient data…

Methodology · Statistics 2025-11-18 Katariina Perkonoja , Kari Auranen , Joni Virta

For sharing privacy-sensitive data, de-identification is commonly regarded as adequate for safeguarding privacy. Synthetic data is also being considered as a privacy-preserving alternative. Recent successes with numerical and tabular data…

Computation and Language · Computer Science 2025-03-05 Atiquer Rahman Sarkar , Yao-Shun Chuang , Noman Mohammed , Xiaoqian Jiang

Synthetic data generation, a cornerstone of Generative Artificial Intelligence, promotes a paradigm shift in data science by addressing data scarcity and privacy while enabling unprecedented performance. As synthetic data becomes more…

Machine Learning · Statistics 2024-03-12 Xiaotong Shen , Yifei Liu , Rex Shen

There is a need for synthetic training and test datasets that replicate statistical distributions of original datasets without compromising their confidentiality. A lot of research has been done in leveraging Generative Adversarial Networks…

Machine Learning · Computer Science 2026-02-06 Laura Plein , Alexi Turcotte , Arina Hallemans , Andreas Zeller

Institutions collect massive learning traces but they may not disclose it for privacy issues. Synthetic data generation opens new opportunities for research in education. In this paper we present a generative model for educational data that…

Computers and Society · Computer Science 2022-07-09 Jill-Jênn Vie , Tomas Rigaux , Sein Minn

Machine learning has the potential to assist many communities in using the large datasets that are becoming more and more available. Unfortunately, much of that potential is not being realized because it would require sharing data in a way…

Machine Learning · Computer Science 2018-07-02 James Jordon , Jinsung Yoon , Mihaela van der Schaar

Generative AI technologies are gaining unprecedented popularity, causing a mix of excitement and apprehension through their remarkable capabilities. In this paper, we study the challenges associated with deploying synthetic data, a subfield…

Machine Learning · Computer Science 2023-07-11 Lauren Arthur , Jason Costello , Jonathan Hardy , Will O'Brien , James Rea , Gareth Rees , Georgi Ganev

Differential privacy allows quantifying privacy loss resulting from accessing sensitive personal data. Repeated accesses to underlying data incur increasing loss. Releasing data as privacy-preserving synthetic data would avoid this…

Machine Learning · Statistics 2021-06-10 Joonas Jälkö , Eemil Lagerspetz , Jari Haukka , Sasu Tarkoma , Antti Honkela , Samuel Kaski

Privacy poses a significant obstacle to the progress of learning analytics (LA), presenting challenges like inadequate anonymization and data misuse that current solutions struggle to address. Synthetic data emerges as a potential remedy,…

Cryptography and Security · Computer Science 2024-01-17 Qinyi Liu , Mohammad Khalil , Ronas Shakya , Jelena Jovanovic

Advances in generative models have transformed the field of synthetic image generation for privacy-preserving data synthesis (PPDS). However, the field lacks a comprehensive survey and comparison of synthetic image generation methods across…

Cryptography and Security · Computer Science 2025-06-27 Yunsung Chung , Yunbei Zhang , Nassir Marrouche , Jihun Hamm

Artificial intelligence (AI) has the potential to transform healthcare, but it requires access to health data. Synthetic data that is generated through machine learning models trained on real data, offers a way to share data while…

Computers and Society · Computer Science 2025-08-13 Vibeke Binz Vallevik , Anne Kjersti C. Befring , Severin Elvatun , Jan Franz Nygaard

The digitization of medical records ushered in a new era of big data to clinical science, and with it the possibility that data could be shared, to multiply insights beyond what investigators could abstract from paper records. The need to…

Machine Learning · Computer Science 2021-06-03 Ofer Mendelevitch , Michael D. Lesh

Synthetic data has been advertised as a silver-bullet solution to privacy-preserving data publishing that addresses the shortcomings of traditional anonymisation techniques. The promise is that synthetic data drawn from generative models…

Machine Learning · Computer Science 2022-01-25 Theresa Stadler , Bristena Oprisanu , Carmela Troncoso

Synthetic data has been considered a better privacy-preserving alternative to traditionally sanitized data across various applications. However, a recent article challenges this notion, stating that synthetic data does not provide a better…

Cryptography and Security · Computer Science 2025-07-28 Fatima Jahan Sarmin , Atiquer Rahman Sarkar , Yang Wang , Noman Mohammed

Genome sequencing technology has advanced at a rapid pace and it is now possible to generate highly-detailed genotypes inexpensively. The collection and analysis of such data has the potential to support various applications, including…

Cryptography and Security · Computer Science 2015-06-18 Muhammad Naveed , Erman Ayday , Ellen W. Clayton , Jacques Fellay , Carl A. Gunter , Jean-Pierre Hubaux , Bradley A. Malin , XiaoFeng Wang