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Biological systems tightly regulate their physiological state using control signals. This includes the actomyosin cytoskeleton, a contractile active gel that consumes chemical free energy to drive many examples of cellular mechanical…

Soft Condensed Matter · Physics 2025-03-03 James Clarke , Francis Cavanna , Aniket Marne , Anthony Davolio , José Alvarado

We study numerically the behaviour of a mixture of a passive isotropic fluid and an active polar gel, in the presence of a surfactant favouring emulsification. Focussing on parameters for which the underlying free energy favours the…

Engineering synthetic materials that mimic the remarkable complexity of living organisms is a fundamental challenge in science and technology. We study the spatiotemporal patterns that emerge when an active nematicfilm of microtubules and…

Activity-mediated unjamming of a confluent glassy system is crucial for several biological processes, such as embryogenesis and cancer metastasis. During these processes, the cells progressively change their junction properties,…

Soft Condensed Matter · Physics 2025-05-13 Souvik Sadhukhan , Chandan Dasgupta , Saroj Kumar Nandi

The self-organization of active particles is governed by their dynamic effective interactions. Such interactions are controlled by the medium in which such active agents reside. Here, we study the interactions between active agents in a…

Soft Condensed Matter · Physics 2016-06-08 J. L. Aragones , J. P. Steimel , A. Alexander-Katz

Active polar fluids exhibit spontaneous flow when sufficient active stress is generated by internal molecular mechanisms. This is also referred to as an active Fr\'{e}edericksz transition. Experiments have revealed the existence of…

Soft Condensed Matter · Physics 2023-10-17 Abhinav Singh , Quentin Vagne , Frank Jülicher , Ivo F. Sbalzarini

Sustained rhythmic oscillations, pulsing dynamics, emerge spontaneously when the local connection scheme is randomised in 3-value cellular automata that feature"glider" dynamics. Time-plots of pulsing measures maintain a distinct waveform…

Cellular Automata and Lattice Gases · Physics 2021-03-02 Andrew Wuensche , Edward Coxon

Biological cells can actively tune their intracellular architecture according to their overall shape. Here we explore the rheological implication of such coupling in a minimal model of a dense cellular material where each cell exerts an…

Soft Condensed Matter · Physics 2022-04-13 Shao-Zhen Lin , Matthias Merkel , Jean-François Rupprecht

A number of factors, such as, cell-cell interactions and self-propulsion of cells driven by cytoskeletal forces determine tissue morphologies and dynamics. To explore the interplay between these factors in controlling the dynamics at the…

Soft Condensed Matter · Physics 2025-05-12 Rajsekhar Das , Xin Li , Sumit Sinha , D. Thirumalai

We propose a model for the dynamics of a probe embedded in a living cell, where both thermal fluctuations and nonequilibrium activity coexist. The model is based on a confining harmonic potential describing the elastic cytoskeletal matrix,…

Biological Physics · Physics 2015-06-18 É. Fodor , M. Guo , N. S. Gov , P. Visco , D. A. Weitz , F. van Wijland

Pattern formation in active biological matter typically arises from the feedback between chemical concentration fields and mechanical stresses. The actomyosin cortex of cells is an archetypal example of an active thin film that displays…

Biological Physics · Physics 2025-10-17 Jason R. Picardo , V. Jemseena , K. Vijay Kumar

When the motion of a motile cell is observed closely, it appears erratic, and yet the combination of nonequilibrium forces and surfaces can produce striking examples of organization in microbial systems. While most of our current…

Active matter embraces systems that self-organize at different length and time scales, often exhibiting turbulent flows. Here, we use a quasi-two-dimensional nematically ordered layer of a protein-based active gel to experimentally…

Soft Condensed Matter · Physics 2017-11-01 Pau Guillamat , Jordi Ignés-Mullol , Francesc Sagués

Phase separating systems that are maintained away from thermodynamic equilibrium via molecular processes represent a class of active systems, which we call active emulsions. These systems are driven by external energy input for example…

Soft Condensed Matter · Physics 2019-06-07 Christoph A. Weber , David Zwicker , Frank Jülicher , Chiu Fan Lee

We study the flow behavior and unjamming transition in dense assemblies of actively deforming particles that periodically change size, a process that we refer to as breathing. Using extensive molecular dynamics simulations and a…

Soft Condensed Matter · Physics 2025-05-21 Sayantan Ghosh , Magali Le Goff , Pinaki Chaudhuri , Kirsten Martens

A flexible membrane deforming its shape in time can self-propel in a viscous fluid. Alternatively, if the membrane is anchored, its deformation will lead to fluid transport. Past work in this area focused on situations where the deformation…

Soft Condensed Matter · Physics 2013-02-12 Arthur A. Evans , Eric Lauga

Active gels play an important role in biology and in inspiring biomimetic active materials, due to their ability to change shape, size and create their own morphology; the relevant mechanics behind these changes is driven by…

Soft Condensed Matter · Physics 2023-09-22 Anne Bernheim-Groswasser , Gefen Livne , Paola Nardinocchi , Filippo Recrosi , Luciano Teresi

Active matter consists of units that generate mechanical work by consuming energy. Examples include living systems, such as assemblies of bacteria and biological tissues, biopolymers driven by molecular motors, and suspensions of synthetic…

Soft Condensed Matter · Physics 2021-02-04 Song Liu , Suraj Shankar , M. Cristina Marchetti , Yilin Wu

The intracellular environment is a dynamic space filled with various organelles moving in all directions. Included in this diverse group of organelles are vesicles, which are involved in transport of molecular cargo throughout the cell.…

Biological Physics · Physics 2018-09-07 Danielle Posey , Paris Blaisdell-Pijuan , Samantha K. Knoll , Taher A. Saif , Wylie W. Ahmed

I put forward a continuum theory for active nematic gels, defined as fluids or suspensions of orientable rodlike objects endowed with active dynamics, that is based on symmetry arguments and compatibility with thermodynamics. The starting…

Soft Condensed Matter · Physics 2017-11-15 Stefano S Turzi