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Disease mapping analyses the distribution of several disease outcomes within a territory. Primary goals include identifying areas with unexpected changes in mortality rates, studying the relation among multiple diseases, and dividing the…

Methodology · Statistics 2025-08-19 Andrea Sottosanti , Enrico Bovo , Pietro Belloni , Giovanna Boccuzzo

In the realm of heterogeneous mixed autonomy, vehicles experience dynamic spatial correlations and nonlinear temporal interactions in a complex, non-Euclidean space. These complexities pose significant challenges to traditional…

Multiagent Systems · Computer Science 2024-08-19 Xin Gao , Zhaoyang Ma , Xueyuan Li , Xiaoqiang Meng , Zirui Li

Multi-parametric magnetic resonance imaging (mpMRI) plays an increasingly important role in the diagnosis of prostate cancer. Various computer-aided detection algorithms have been proposed for automated prostate cancer detection by…

Applications · Statistics 2020-01-22 Jin Jin , Lin Zhang , Ethan Leng , Gregory J. Metzger , Joseph S. Koopmeiners

Medical researchers are coming to appreciate that many diseases are in fact complex, heterogeneous syndromes composed of subpopulations that express different variants of a related complication. Time series data extracted from individual…

Machine Learning · Statistics 2016-06-30 Peter Schulam , Raman Arora

This work is motivated by multimodality breast cancer imaging data, which is quite challenging in that the signals of discrete tumor-associated microvesicles (TMVs) are randomly distributed with heterogeneous patterns. This imposes a…

Machine Learning · Statistics 2019-03-22 Xiwei Tang , Xuan Bi , Annie Qu

We propose an approach termed ``qDAGx'' for Bayesian covariate-dependent quantile directed acyclic graphs (DAGs) where these DAGs are individualized, in the sense that they depend on individual-specific covariates. The individualized DAG…

Methodology · Statistics 2023-05-24 Ksheera Sagar , Yang Ni , Veerabhadran Baladandayuthapani , Anindya Bhadra

Multivariate spatial disease mapping has become a pivotal part of everyday practice in social epidemiology. Despite the existence of several specifications for the relation between different outcomes, there is still a need for a new…

Applications · Statistics 2024-10-30 P. Escobar-Hernández , A. López-Quílez , F. Palmí-Perales , M. Marco

Simulations are ubiquitous in machine learning. Especially in graph learning, simulations of Directed Acyclic Graphs (DAG) are being deployed for evaluating new algorithms. In the literature, it was recently argued that…

Machine Learning · Computer Science 2022-06-16 Jonas Seng , Matej Zečević , Devendra Singh Dhami , Kristian Kersting

Appropriate models for spatially autocorrelated data account for the fact that observations are not independent. A popular model in this context is the simultaneous autoregressive (SAR) model that allows to model the spatial dependency…

Methodology · Statistics 2017-07-12 A. Kreuzer , T. Erhardt , T. Nagler , C. Czado

In this paper, we introduce a new spatial model that incorporates heteroscedastic variance depending on neighboring locations. The proposed process is regarded as the spatial equivalent to the temporal autoregressive conditional…

Statistics Theory · Mathematics 2020-10-20 Philipp Otto , Wolfgang Schmid , Robert Garthoff

Multi-modal data comprising imaging (MRI, fMRI, PET, etc.) and non-imaging (clinical test, demographics, etc.) data can be collected together and used for disease prediction. Such diverse data gives complementary information about the…

Machine Learning · Computer Science 2018-12-27 Anees Kazi , S. Arvind krishna , Shayan Shekarforoush , Karsten Kortuem , Shadi Albarqouni , Nassir Navab

We consider the problem of estimating the differences between two causal directed acyclic graph (DAG) models with a shared topological order given i.i.d. samples from each model. This is of interest for example in genomics, where changes in…

Methodology · Statistics 2018-11-08 Yuhao Wang , Chandler Squires , Anastasiya Belyaeva , Caroline Uhler

Model-based disease mapping remains a fundamental policy-informing tool in the fields of public health and disease surveillance. Hierarchical Bayesian models have emerged as the state-of-the-art approach for disease mapping since they are…

Machine Learning · Computer Science 2023-07-18 Elizaveta Semenova , Swapnil Mishra , Samir Bhatt , Seth Flaxman , H Juliette T Unwin

We investigate spatial confounding in the presence of multivariate disease dependence. In the "analysis model perspective" of spatial confounding, adding a spatially dependent random effect can lead to significant variance inflation of the…

Methodology · Statistics 2026-02-13 Kyle Lin Wu , Sudipto Banerjee

Prevalence mapping in low resource settings is an increasingly important endeavor to guide policy making and to spatially and temporally characterize the burden of disease. We will focus our discussion on consideration of the complex design…

Methodology · Statistics 2016-08-15 Jon Wakefield , Daniel Simpson , Jessica Godwin

Graphical models are powerful tools to investigate complex dependency structures in high-throughput datasets. However, most existing graphical models make one of the two canonical assumptions: (i) a homogeneous graph with a common network…

Methodology · Statistics 2023-10-31 Tsung-Hung Yao , Yang Ni , Anindya Bhadra , Jian Kang , Veerabhadran Baladandayuthapani

We propose a joint order-based scoring framework for causal structure learning of directed acyclic graph (DAG) models under heterogeneous data settings. We show that leveraging heterogeneity improves the accuracy of causal ordering…

Methodology · Statistics 2026-05-18 Hyunwoong Chang , Fariha Taskin

To date, we have seen the emergence of a large literature on multivariate disease mapping. That is, incidence of (or mortality from) multiple diseases is recorded at the scale of areal units where incidence (mortality) across the diseases…

Methodology · Statistics 2026-04-17 Garazi Retegui , María Dolores Ugarte , Jaione Etxeberria , Alan E. Gelfand

Benefiting from the powerful expressive capability of graphs, graph-based approaches have achieved impressive performance in various biomedical applications. Most existing methods tend to define the adjacency matrix among samples manually…

Machine Learning · Computer Science 2021-07-02 Shuai Zheng , Zhenfeng Zhu , Zhizhe Liu , Zhenyu Guo , Yang Liu , Yao Zhao

Envelope model also known as multivariate regression model was proposed to solve the multiple response regression problems. It measures the linear association between predictors and multiple responses by using the minimal reducing subspace…

Methodology · Statistics 2018-05-07 Bochao Jia