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Despite the widespread testing protocols for COVID-19, there are still significant challenges in early detection of the disease, which is crucial for preventing its spread and optimizing patient outcomes. Owing to the limited testing…

Machine Learning · Computer Science 2023-12-13 Moyosolu Akinloye

Epidemiological forecasts are beset by uncertainties about the underlying epidemiological processes, and the surveillance process through which data are acquired. We present a Bayesian inference methodology that quantifies these…

Large Language Models (LLMs) hold great promise to revolutionize current clinical systems for their superior capacities on medical text processing tasks and medical licensing exams. Meanwhile, traditional ML models such as SVM and XGBoost…

Computation and Language · Computer Science 2024-11-12 Canyu Chen , Jian Yu , Shan Chen , Che Liu , Zhongwei Wan , Danielle Bitterman , Fei Wang , Kai Shu

Machine learning (ML) models have been quite successful in predicting outcomes in many applications. However, in some cases, domain experts might have a judgment about the expected outcome that might conflict with the prediction of ML…

Machine Learning · Computer Science 2023-05-02 Hogun Park , Aly Megahed , Peifeng Yin , Yuya Ong , Pravar Mahajan , Pei Guo

Motivated by chemical reaction rules, we introduce a rule-based epidemiological framework for the systematic mathematical modelling of future pandemics. Here we stress that we do not have a specific model in mind, but a whole collection of…

Populations and Evolution · Quantitative Biology 2024-05-24 David Alonso , Steffen Bauer , Markus Kirkilionis , Lisa Maria Kreusser , Luca Sbano

There is growing interest in hypothesis generation with large language models (LLMs). However, fundamental questions remain: what makes a good hypothesis, and how can we systematically evaluate methods for hypothesis generation? To address…

Artificial Intelligence · Computer Science 2026-02-12 Haokun Liu , Sicong Huang , Jingyu Hu , Yangqiaoyu Zhou , Chenhao Tan

Developing safe, effective, and practically useful clinical prediction models (CPMs) traditionally requires iterative collaboration between clinical experts, data scientists, and informaticists. This process refines the often small but…

Artificial Intelligence · Computer Science 2026-01-15 Jean Feng , Avni Kothari , Patrick Vossler , Andrew Bishara , Lucas Zier , Newton Addo , Aaron Kornblith , Yan Shuo Tan , Chandan Singh

This paper quantitatively reveals the state-of-the-art and state-of-the-practice AI systems only achieve acceptable performance on the stringent conditions that all categories of subjects are known, which we call closed clinical settings,…

COVID-19 had an unprecedented impact on scientific collaboration. The pandemic and its broad response from the scientific community has forged new relationships among domain experts, mathematical modelers, and scientific computing…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-05-11 Nicholson Collier , Justin M. Wozniak , Abby Stevens , Yadu Babuji , Mickaël Binois , Arindam Fadikar , Alexandra Würth , Kyle Chard , Jonathan Ozik

The COVID-19 pandemic has emphasized the need for a robust understanding of epidemic models. Current models of epidemics are classified as either mechanistic or non-mechanistic: mechanistic models make explicit assumptions on the dynamics…

Machine Learning · Statistics 2022-01-14 Arnab Sarker , Ali Jadbabaie , Devavrat Shah

Predictive models are increasingly used to make various consequential decisions in high-stakes domains such as healthcare, finance, and policy. It becomes critical to ensure that these models make accurate predictions, are robust to shifts…

Machine Learning · Computer Science 2022-09-22 Murtuza N Shergadwala , Himabindu Lakkaraju , Krishnaram Kenthapadi

In the rapidly evolving field of artificial intelligence (AI), traditional benchmarks can fall short in attempting to capture the nuanced capabilities of AI models. We focus on the case of physical world modeling and propose a novel…

Artificial Intelligence · Computer Science 2025-09-08 Sasha Mitts

Producing high-quality forecasts of key climate variables, such as temperature and precipitation, on subseasonal time scales has long been a gap in operational forecasting. This study explores an application of machine learning (ML) models…

Machine Learning · Computer Science 2024-09-17 Elena Orlova , Haokun Liu , Raphael Rossellini , Benjamin A. Cash , Rebecca Willett

Providing accurate and reliable predictions about the future of an epidemic is an important problem for enabling informed public health decisions. Recent works have shown that leveraging data-driven solutions that utilize advances in deep…

Machine Learning · Computer Science 2023-11-21 Harshavardhan Kamarthi , B. Aditya Prakash

Modelling epidemic events such as COVID-19 cases in both time and space dimensions is an important but challenging task. Building on in-depth review and assessment of two popular graph neural network (GNN)-based regional epidemic…

Computation · Statistics 2025-11-20 Xiangxin Kong , Hang Wang , Yutong Li , Yanghao Chen , Zudi Lu

The lack of standardization in seizure forecasting slows progress in the field and limits the clinical translation of forecasting models. In this work, we introduce a Python-based framework aimed at streamlining the development, assessment,…

Quantitative Methods · Quantitative Biology 2025-10-14 Ana Sofia Carmo , Lourenço Abrunhosa Rodrigues , Ana Rita Peralta , Ana Fred , Carla Bentes , Hugo Plácido da Silva

Advances in deep learning systems have allowed large models to match or surpass human accuracy on a number of skills such as image classification, basic programming, and standardized test taking. As the performance of the most capable…

Machine Learning · Computer Science 2024-06-10 Sarah Pratt , Seth Blumberg , Pietro Kreitlon Carolino , Meredith Ringel Morris

Machine learning has recently demonstrated impressive progress in predictive accuracy across a wide array of tasks. Most ML approaches focus on generalization performance on unseen data that are similar to the training data…

Machine Learning · Computer Science 2021-07-20 Anand Avati , Martin Seneviratne , Emily Xue , Zhen Xu , Balaji Lakshminarayanan , Andrew M. Dai

Controlling infectious diseases is a major health priority because they can spread and infect humans, thus evolving into epidemics or pandemics. Therefore, early detection of infectious diseases is a significant need, and many researchers…

Machine Learning · Computer Science 2022-06-16 Eman Yahia Alqaissi , Fahd Saleh Alotaibi , Muhammad Sher Ramzan

Solving expert-level multimodal tasks is a key milestone towards general intelligence. As the capabilities of multimodal large language models (MLLMs) continue to improve, evaluation of such advanced multimodal intelligence becomes…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Yan Yang , Dongxu Li , Haoning Wu , Bei Chen , Liu Liu , Liyuan Pan , Junnan Li