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We conduct a systematic exploration of the energy landscape of vesicle morphologies within the framework of the Helfrich model. Vesicle shapes are determined by minimizing the elastic energy subject to constraints of constant area and…

Soft Condensed Matter · Physics 2023-11-27 Rodrigo B. Reboucas , Hammad A. Faizi , Michael J. Miksis , Petia M. Vlahovska

The internal dynamics of active gels, both in artificial (in-vitro) model systems and inside the cytoskeleton of living cells, has been extensively studied by experiments of recent years. These dynamics are probed using tracer particles…

Soft Condensed Matter · Physics 2015-07-28 E. Ben Isaac , É. Fodor , P. Visco , F. van Wijland , N. S. Gov

The deformation and rupture of a lipid vesicle due to the forced normal approach of an inclusion are essential for optimizing the design of magnetic giant unilamellar vesicles [magGUVs, Malik et al., Nanoscale 17, 13720 (2025)], with…

Soft Condensed Matter · Physics 2025-12-16 Yuan-Nan Young , Bryan Quaife , Herve Nganguia , On Shun Pak , Jie Feng , Howard A. Stone

We simulate the nonlocal Stokesian hydrodynamics of an elastic filament which is active due a permanent distribution of stresslets along its contour. A bending instability of an initially straight filament spontaneously breaks flow symmetry…

Active soft bodies can affect their shape through an internal actuation mechanism that induces a deformation. Similar to recent work, this paper utilizes a differentiable, quasi-static, and physics-based simulation layer to optimize for…

Computer Vision and Pattern Recognition · Computer Science 2024-01-29 Lingchen Yang , Byungsoo Kim , Gaspard Zoss , Baran Gözcü , Markus Gross , Barbara Solenthaler

Pattern-forming metamaterials feature microstructures specifically designed to change the material's macroscopic properties due to internal instabilities. These can be triggered either by mechanical deformation or, in the case of active…

We consider a three-dimensional network of aqueous droplets joined by single lipid bilayers to form a cohesive, tissue-like material. The droplets in these networks can be programmed to have distinct osmolarities so that osmotic gradients…

Soft Condensed Matter · Physics 2016-03-23 T. Zhang , Duanduan Wan , J. M. Schwarz , M. J. Bowick

We present a microscopic model of a disordered viscoelastic active solid, i.e. an active material whose long time behaviour is elastic as opposed to viscous. It is composed of filaments, passive crosslinks and molecular motors powered by…

Soft Condensed Matter · Physics 2014-07-15 Rhoda J. Hawkins , Tanniemola B. Liverpool

We introduce a phenomenological model to study the properties of bundles of polar filaments which interact via active elements. The stability of the homogeneous state, the attractors of the dynamics in the unstable regime and the tensile…

Statistical Mechanics · Physics 2009-10-31 Karsten Kruse , Frank Julicher

We present a continuum model of the coupling between cells and substrate that accounts for some of the observed substrate-stiffness dependence of cell properties. The cell is modeled as an elastic active gel, adapting recently developed…

Cell Behavior · Quantitative Biology 2015-05-28 Shiladitya Banerjee , M. Cristina Marchetti

Lipid bilayer membranes have a native (albeit small) permeability for water molecules. Under an external load, provided that the bilayer structure stays intact and does not suffer from poration or rupture, a lipid membrane deforms and its…

Soft Condensed Matter · Physics 2021-07-14 Bryan Quaife , Ashley Gannon , Y. -N. Young

In this work, we compare the structural and dynamic behavior of active filaments in two dimensions using tangential and push-pull models, including a variant with passive end monomers. These models serve as valuable frameworks for…

We investigate theoretically the collective dynamics of soft active particles living in a viscous fluid. We focus on a minimal model for active but non-motile particles consisting of $N>1$ elastic dimers deformed by active stresses and…

Soft Condensed Matter · Physics 2010-04-09 Denis Bartolo , Eric Lauga

As a model of soft confinement for polymers, we investigated equilibrium shapes of a flexible vesicle that contains a phase-separating polymer solution. To simulate such a system, we combined the phase field theory (PFT) for the vesicle and…

Biological Physics · Physics 2015-06-19 Yutaka Oya , Toshihiro Kawakatsu

Spontaneous emergence of organized states in materials driven by non-equilibrium conditions is of significant fundamental and technological interest. In many cases, the organized states are complex, hence, with some well-studied exceptions,…

Soft Condensed Matter · Physics 2021-09-17 Geet Raju , Nikos Kyriakopoulos , Jaakko V. I. Timonen

We study the deformations of elastic filaments confined within slowly-shrinking circular boundaries, under contact forces with friction. We perform computations with a spring-lattice model that deforms like a thin inextensible filament of…

Soft Condensed Matter · Physics 2022-02-23 Silas Alben

Connecting cell behavior to tissue shape and mechanics is a key challenge in the physics of morphogenesis. Cytoskeletal turnover precludes a fixed reference state, and tensions are actively generated independently of strain; so conventional…

Soft Condensed Matter · Physics 2026-05-28 Nikolas H. Claussen , Fridtjof Brauns , Boris I. Shraiman

Active nematics are out-of-equilibrium systems in which energy injection at the microscale drives emergent collective behaviors, from spontaneous flows to active turbulence. While the dynamics of these systems have been extensively studied,…

Soft Condensed Matter · Physics 2025-04-15 Ahmet Umut Akduman , Yusuf Sariyar , Giuseppe Negro , Livio Nicola Carenza

Mixtures of active and passive particles are ubiquitous at the microscale. Many essential microbial processes involve interactions with dead or immotile cells or passive crowders. When passive objects are immersed in active baths, their…

Soft Condensed Matter · Physics 2026-02-24 Horacio Serna , C. Miguel Barriuso G. , Ignacio Pagonabarraga , Marco Polin , Chantal Valeriani

The equilibrium state of a flexible fiber settling in a viscous fluid is examined using a combination of macroscopic experiments, numerical simulations and scaling arguments. We identify three regimes having different signatures on this…