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Active stresses in biological cells and tissues drive many developmental processes. However, increasing experimental evidence suggests that additional mechanical interactions with surrounding material can play a crucial role in guiding…

Soft Condensed Matter · Physics 2026-03-10 Douglas MacMyn Brown , Alexander Mietke

Active matter drives its constituent agents to move autonomously by harnessing free energy, leading to diverse emergent states with relevance to both biological processes and inanimate functionalities. Achieving maximum reconfigurability of…

Soft Condensed Matter · Physics 2024-03-05 Qianhong Yang , Maoqiang Jiang , Francesco Picano , Lailai Zhu

The interplay between active matter and its environment is central to understanding emergent behavior in biological and synthetic systems. Here, we show that coupling active nematic flows to small-amplitude deformations of a compliant…

Soft Condensed Matter · Physics 2026-01-19 Varun Venkatesh , Amin Doostmohammadi

Using numerical simulations, we characterized the behavior of an elastic membrane immersed in an active fluid. Our findings reveal a nontrivial folding and re-expansion of the membrane that is controlled by the interplay of its resistance…

Soft Condensed Matter · Physics 2015-07-24 S. A. Mallory , C. Valeriani , A. Cacciuto

Hollow microgels are elastic polymer shells easily realizable in experiments. Recent works have shown the emergence of buckling events in dilute hollow microgels under the effect of an added osmotic pressure. Here, we perform large-scale…

Soft Condensed Matter · Physics 2026-01-19 Leah Rank , Emanuela Zaccarelli

The organization of live cells to tissues is associated with the mechanical interaction between cells, which is mediated through their elastic environment. We model cells as spherical active force dipoles surrounded by an infinite elastic…

Biological Physics · Physics 2017-06-08 Roman Golkov , Yair Shokef

We theoretically study the behavior of vesicles filled with a liquid of higher density than the surrounding medium, a technique frequently used in experiments. In the presence of gravity, these vesicles sink to the bottom of the container,…

Condensed Matter · Physics 2009-10-28 Martin Kraus , Udo Seifert , Reinhard Lipowsky

We show that a viscoelastic thin sheet driven out of equilibrium by active structural remodelling develops a rich variety of shapes as a result of a competition between viscous relaxation and activity. In the regime where active processes…

Soft Condensed Matter · Physics 2020-02-26 D. A. Matoz-Fernandez , Fordyce A. Davidson , Nicola R. Stanley-Wall , Rastko Sknepnek

Motor proteins drive persistent motion and self-organisation of cytoskeletal filaments. However, state-of-the-art microscopy techniques and continuum modelling approaches focus on large length and time scales. Here, we perform…

Soft Condensed Matter · Physics 2024-06-03 Gerrit Vliegenthart , Arvind Ravichandran , Marisol Ripoll , Thorsten Auth , Gerhard Gompper

Motivated to understand the behavior of biological filaments interacting with membranes of various types, we study a theoretical model for the shape and thermodynamics of intrinsically-helical filaments bound to curved membranes. We show…

Soft Condensed Matter · Physics 2016-11-03 D. A. Quint , A. Gopinathan , G. M. Grason

In biology, cells undergo deformations under the action of flow caused by the fluid surrounding them. These flows lead to shape changes and instabilities that have been explored in detail for single component vesicles. However, cell…

Fluid Dynamics · Physics 2025-10-15 Anirudh Venkatesh , Vivek Narsimhan

Active materials take advantage of their internal sources of energy to self-organize in an automated manner. This feature provides a novel opportunity to design micron-scale machines with minimal required control. However, self-organization…

Soft Condensed Matter · Physics 2021-01-22 Zijie Qu , Jialong Jiang , Heun Jin Lee , Rob Phillips , Shahriar Shadkhoo , Matt Thomson

Biological membranes are host to proteins and molecules which may form domain-like structures resulting in spatially-varying material properties. Vesicles with such heterogeneous membranes can exhibit intricate shapes at equilibrium and…

Soft Condensed Matter · Physics 2023-06-22 Prerna Gera , David Salac , Saverio E. Spagnolie

Soft matters whose constituents are deformable are ubiquitous in nature especially in biological systems-including cells and their organelles-as well as in foams and emulsions. The capacity for deformation in these soft materials gives rise…

Soft Condensed Matter · Physics 2026-03-05 Padmanabha Bose , Smarajit Karmakar

Confinement can significantly alter fluid properties, offering potential for specific technological applications. However, achieving precise control over the structural complexity of confined fluids and soft matter remains challenging, as…

Soft Condensed Matter · Physics 2024-11-20 Fabio Leoni , Erdal C. Oğuz , Giancarlo Franzese

We study the dynamics and patterning of polar contractile filaments on the surface of a cylindrical cell using active hydrodynamic equations that incorporate couplings between curvature and filament orientation. Cables and rings…

Soft Condensed Matter · Physics 2015-06-05 Pragya Srivastava , Roie Shlomovitz , Nir S. Gov , Madan Rao

In active matter systems, self-propelled particles can self-organize to undergo collective motion, leading to persistent dynamical behavior out of equilibrium. In cells, cytoskeletal filaments and motor proteins self-organize into complex…

Soft Condensed Matter · Physics 2020-05-19 Jeffrey M. Moore , Tyler N. Thompson , Matthew A. Glaser , Meredith D. Betterton

Soft, amorphous solids such as tissues, foams, and emulsions are composed of deformable particles. However, the effect of single-particle deformability on the collective behavior of soft solids is still poorly understood. We perform…

Soft Condensed Matter · Physics 2021-06-02 John D. Treado , Dong Wang , Arman Boromand , Michael P. Murrell , Mark D. Shattuck , Corey S. O'Hern

Spontaneous growth of long-wavelength deformations is a defining feature of active fluids with orientational order. We investigate the effect of biaxial rectangular confinement on the instability of initially shear-aligned 3D isotropic…

Soft Condensed Matter · Physics 2021-01-04 Pooja Chandrakar , Minu Varghese , S. Ali Aghvami , Aparna Baskaran , Zvonimir Dogic , Guillaume Duclos

In most practical situations, active particles are affected by their environment, for example, by a chemical concentration gradient, light intensity, gravity, or confinement. In particular, the effect of an external flow field is important…

Soft Condensed Matter · Physics 2017-09-13 Mitsusuke Tarama