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Many approaches in the field of machine learning and data analysis rely on the assumption that the observed data lies on lower-dimensional manifolds. This assumption has been verified empirically for many real data sets. To make use of this…

Machine Learning · Computer Science 2022-09-27 Erik Thordsen , Erich Schubert

Simultaneously optimizing multiple, frequently conflicting, molecular properties is a key bottleneck in the development of novel therapeutics. Although a promising approach, the efficacy of multi-task learning is often compromised by…

Machine Learning · Computer Science 2025-10-01 Mason Minot , Gisbert Schneider

Despite the exceptional reasoning capabilities of Multimodal Large Language Models (MLLMs), their adaptation into universal embedding models is significantly impeded by task conflict. To address this, we propose TSEmbed, a universal…

Computation and Language · Computer Science 2026-03-06 Yebo Wu , Feng Liu , Ziwei Xie , Zhiyuan Liu , Changwang Zhang , Jun Wang , Li Li

We studied a generalized question: chronic diseases like ME/CFS and long COVID exhibit high heterogeneity with multifactorial etiology and progression, complicating diagnosis and treatment. To address this, we developed BioMapAI, an…

Genomics · Quantitative Biology 2025-06-23 Ruoyun Xiong

Deep learning-based medical image segmentation and surface mesh generation typically involve a sequential pipeline from image to segmentation to meshes, often requiring large training datasets while making limited use of prior geometric…

Foundational models, pretrained on a large scale, have demonstrated substantial success across non-medical domains. However, training these models typically requires large, comprehensive datasets, which contrasts with the smaller and more…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Raphael Schäfer , Till Nicke , Henning Höfener , Annkristin Lange , Dorit Merhof , Friedrich Feuerhake , Volkmar Schulz , Johannes Lotz , Fabian Kiessling

Computer-aided diagnosis (CAD) systems play a crucial role in analyzing neuroimaging data for neurological and psychiatric disorders. However, small-sample studies suffer from low reproducibility, while large-scale datasets introduce…

Machine Learning · Computer Science 2025-08-12 Xinglin Zhao , Yanwen Wang , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen

Motivation: State-of-the-art biomedical named entity recognition (BioNER) systems often require handcrafted features specific to each entity type, such as genes, chemicals and diseases. Although recent studies explored using neural network…

Information Retrieval · Computer Science 2018-10-09 Xuan Wang , Yu Zhang , Xiang Ren , Yuhao Zhang , Marinka Zitnik , Jingbo Shang , Curtis Langlotz , Jiawei Han

State-of-the-art studies have demonstrated the superiority of joint modelling over pipeline implementation for medical named entity recognition and normalization due to the mutual benefits between the two processes. To exploit these…

Computation and Language · Computer Science 2018-12-17 Sendong Zhao , Ting Liu , Sicheng Zhao , Fei Wang

Many recent medical segmentation systems rely on powerful deep learning models to solve highly specific tasks. To maximize performance, it is standard practice to evaluate numerous pipelines with varying model topologies, optimization…

Machine Learning · Computer Science 2019-11-06 Mathias Perslev , Erik Bjørnager Dam , Akshay Pai , Christian Igel

Molecular sciences address a wide range of problems involving molecules of different types and sizes and their complexes. Recently, geometric deep learning, especially Graph Neural Networks, has shown promising performance in molecular…

Machine Learning · Computer Science 2023-11-21 Shuo Zhang , Yang Liu , Lei Xie

This paper presents a framework for deep transfer learning, which aims to leverage information from multi-domain upstream data with a large number of samples $n$ to a single-domain downstream task with a considerably smaller number of…

Machine Learning · Computer Science 2025-01-07 Yuling Jiao , Huazhen Lin , Yuchen Luo , Jerry Zhijian Yang

We introduce a cutting-edge video compression framework tailored for the age of ubiquitous video data, uniquely designed to serve machine learning applications. Unlike traditional compression methods that prioritize human visual perception,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-25 Huan Cui , Qing Li , Hanling Wang , Yong jiang

Artificial intelligence holds strong potential to support clinical decision making in intensive care units where timely and accurate risk assessment is critical. However, many existing models focus on isolated outcomes or limited data…

Relatively abundant availability of medical imaging data has provided significant support in the development and testing of Neural Network based image processing methods. Clinicians often face issues in selecting suitable image processing…

Image and Video Processing · Electrical Eng. & Systems 2021-09-10 Mayank Goswami

In this work, we present a general framework for building a biometrics system capable of capturing multispectral data from a series of sensors synchronized with active illumination sources. The framework unifies the system design for…

Computer Vision and Pattern Recognition · Computer Science 2020-06-16 Leonidas Spinoulas , Mohamed Hussein , David Geissbühler , Joe Mathai , Oswin G. Almeida , Guillaume Clivaz , Sébastien Marcel , Wael AbdAlmageed

In the rapidly evolving landscape of medical imaging diagnostics, achieving high accuracy while preserving computational efficiency remains a formidable challenge. This work presents \texttt{DeepMediX}, a groundbreaking, resource-efficient…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Kishore Babu Nampalle , Pradeep Singh , Uppala Vivek Narayan , Balasubramanian Raman

Accurate dental diagnosis is essential for oral healthcare, yet many individuals lack access to timely professional evaluation. Existing AI-based methods primarily treat diagnosis as a visual pattern recognition task and do not reflect the…

The rapid advancement of high-throughput sequencing and other assay technologies has resulted in the generation of large and complex multi-omics datasets, offering unprecedented opportunities for advancing precision medicine strategies.…

Quantitative Methods · Quantitative Biology 2025-01-30 Ana R. Baião , Zhaoxiang Cai , Rebecca C Poulos , Phillip J. Robinson , Roger R Reddel , Qing Zhong , Susana Vinga , Emanuel Gonçalves

Transformer is a popularly used neural network architecture, especially for language understanding. We introduce an extended and unified architecture that can be used for tasks involving a variety of modalities like image, text, videos,…

Machine Learning · Computer Science 2020-07-06 Subhojeet Pramanik , Priyanka Agrawal , Aman Hussain