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Stochastic models of biochemical reaction networks are widely used to capture intrinsic noise in cellular systems. The typical formulation of these models are based on Markov processes for which there is extensive research on efficient…

Molecular Networks · Quantitative Biology 2025-12-03 Thomas P. Steele , David J. Warne

Stochastic models of reaction networks are becoming increasingly important in Systems Biology. In these models, the dynamics is generally represented by a continuous-time Markov chain whose states denote the copy-numbers of the constituent…

Probability · Mathematics 2018-02-12 Ankit Gupta , Mustafa Khammash

The modelling and analysis of biological systems has deep roots in Mathematics, specifically in the field of ordinary differential equations (ODEs). Alternative approaches based on formal calculi, often derived from process algebras or term…

Programming Languages · Computer Science 2010-11-03 Mario Coppo , Ferruccio Damiani , Maurizio Drocco , Elena Grassi , Eva Sciacca , Salvatore Spinella , Angelo Troina

We study the averaging-based distributed optimization solvers over random networks. We show a general result on the convergence of such schemes using weight-matrices that are row-stochastic almost surely and column-stochastic in expectation…

Optimization and Control · Mathematics 2020-10-06 Adel Aghajan , Behrouz Touri

Combinatorial harmonic analysis techniques are used to develop new functional analysis methods based on Bogoliubov functionals. Concrete applications of the methods are presented, namely, the study of a non-equilibrium stochastic dynamics…

Mathematical Physics · Physics 2011-01-04 Yuri G. Kondratiev , Tobias Kuna , Maria Joao Oliveira

Many regenerative arguments in stochastic processes use random times which are akin to stopping times, but which are determined by the future as well as the past behaviour of the process of interest. Such arguments based on "conditioning on…

Probability · Mathematics 2014-10-09 Sergey Foss , Stan Zachary

A theory of systems with long-range correlations based on the consideration of binary N-step Markov chains is developed. In the model, the conditional probability that the i-th symbol in the chain equals zero (or unity) is a linear function…

Data Analysis, Statistics and Probability · Physics 2016-09-08 O. V. Usatenko , V. A. Yampol'skii , K. E. Kechedzhy , S. S. Mel'nyk

The concept of a system has proliferated through natural and social sciences. While myriad theories of systems exist, there is no mathematical general theory of systems. In this thesis, we take a first step towards formulating such a…

Category Theory · Mathematics 2019-06-14 Daniel Cicala

Causal reversibility blends reversibility and causality for concurrent systems. It indicates that an action can be undone provided that all of its consequences have been undone already, thus making it possible to bring the system back to a…

Logic in Computer Science · Computer Science 2024-02-14 Marco Bernardo , Claudio A. Mezzina

One of the proposed solutions to the equilibrium selection problem for agents learning in repeated games is obtained via the notion of stochastic stability. Learning algorithms are perturbed so that the Markov chain underlying the learning…

Computer Science and Game Theory · Computer Science 2012-07-09 John Wicks , Amy Greenwald

In this study, we consider the numerical solution of large systems of linear equations obtained from the stochastic Galerkin formulation of stochastic partial differential equations. We propose an iterative algorithm that exploits the…

Numerical Analysis · Mathematics 2016-05-18 Kookjin Lee , Howard C. Elman

We develop a general model theoretic semantics to rewriting beyond the usual confluence and termination assumptions. This is based on preordered algebra which is a model theory that extends many sorted algebra. In this framework we…

Logic · Mathematics 2022-04-27 Răzvan Diaconescu

We study stochastic combinatorial optimization problems where the objective is to minimize the expected maximum load (a.k.a.\ the makespan). In this framework, we have a set of $n$ tasks and $m$ resources, where each task $j$ uses some…

Data Structures and Algorithms · Computer Science 2021-06-25 Anupam Gupta , Amit Kumar , Viswanath Nagarajan , Xiangkun Shen

Binding and unbinding of ligands to specific sites of a macromolecule are one of the most elementary molecular interactions inside the cell that embody the computational processes of biological regulations. The interaction between…

Molecular Networks · Quantitative Biology 2011-11-10 Hidenori Kimura , Hiroyuki Okano , Reiko J. Tanaka

We extend the Markov chain tree theorem to general commutative semirings, and we generalize the state reduction algorithm to commutative semifields. This leads to a new universal algorithm, whose prototype is the state reduction algorithm…

Combinatorics · Mathematics 2022-07-11 Buket Benek Gursoy , Steve Kirkland , Oliver Mason , Sergei Sergeev

This article presents a short and concise description of stochastic approximation algorithms in reinforcement learning of Markov decision processes. The algorithms can also be used as a suboptimal method for partially observed Markov…

Optimization and Control · Mathematics 2015-12-25 Vikram Krishnamurthy

Inspired from modern out-of-equilibrium statistical physics models, a matrix product based framework permits the formal definition of random vectors (and random time series) whose desired joint distributions are a priori prescribed. Its key…

Statistical Mechanics · Physics 2012-03-21 Florian Angeletti , Eric Bertin , Patrice Abry

Probabilistic forecasting relies on past observations to provide a probability distribution for a future outcome, which is often evaluated against the realization using a scoring rule. Here, we perform probabilistic forecasting with…

Machine Learning · Statistics 2024-03-06 Lorenzo Pacchiardi , Rilwan Adewoyin , Peter Dueben , Ritabrata Dutta

For a Markov chain both the detailed balance condition and the cycle Kolmogorov condition are algebraic binomials. This remark suggests to study reversible Markov chains with the tool of Algebraic Statistics, such as toric statistical…

Statistics Theory · Mathematics 2011-03-31 Giovanni Pistone , Maria Piera Rogantin

Markov processes restarted or reset at random times to a fixed state or region in space have been actively studied recently in connection with random searches, foraging, and population dynamics. Here we study the large deviations of…

Statistical Mechanics · Physics 2016-01-06 Janusz M. Meylahn , Sanjib Sabhapandit , Hugo Touchette