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Data frames in scripting languages are essential abstractions for processing structured data. However, existing data frame solutions are either not distributed (e.g., Pandas in Python) and therefore have limited scalability, or they are not…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-04-11 Ehsan Totoni , Wajih Ul Hassan , Todd A. Anderson , Tatiana Shpeisman

Recommendation systems are of crucial importance for a variety of modern apps and web services, such as news feeds, social networks, e-commerce, search, etc. To achieve peak prediction accuracy, modern recommendation models combine deep…

Information Retrieval · Computer Science 2022-10-18 Yingcan Wei , Matthias Langer , Fan Yu , Minseok Lee , Kingsley Liu , Jerry Shi , Joey Wang

Similarity search, the task of identifying objects most similar to a given query object under a specific metric, has gathered significant attention due to its practical applications. However, the absence of coordinate information to…

Databases · Computer Science 2024-05-14 Yifan Zhu , Ruiyao Ma , Baihua Zheng , Xiangyu Ke , Lu Chen , Yunjun Gao

Breadth-first search (BFS) is a fundamental graph algorithm that presents significant challenges for parallel implementation due to irregular memory access patterns, load imbalance and synchronization overhead. In this paper, we introduce a…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-04 Marati Bhaskar , Raghavendra Kanakagiri

Many large-scale applications amount to finding relevant results from an enormous output space of potential candidates. For example, finding the best matching product from a large catalog or suggesting related search phrases on a search…

Machine Learning · Computer Science 2022-01-20 Hsiang-Fu Yu , Kai Zhong , Jiong Zhang , Wei-Cheng Chang , Inderjit S. Dhillon

Statistically meaningful comparison/combination of peptide identification results from various search methods is impeded by the lack of a universal statistical standard. Providing an E-value calibration protocol, we demonstrated earlier the…

Quantitative Methods · Quantitative Biology 2010-09-20 Gelio Alves , Aleksey Y. Ogurtsov , Yi-Kuo Yu

MPI applications matter. However, with the advent of many-core processors, traditional MPI applications are challenged to achieve satisfactory performance. This is due to the inability of these applications to respond to load imbalances, to…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-12-20 Jan Ciesko , Pedro J. Martínez-Ferrer , Raúl Peñacoba Veigas , Xavier Teruel , Vicenç Beltran

Hyperdimensional Computing (HDC) is a bio-inspired computing framework that has gained increasing attention, especially as a more efficient approach to machine learning (ML). This work introduces the \name{} compiler, the first open-source…

Machine Learning · Computer Science 2023-04-26 Pere Vergés , Mike Heddes , Igor Nunes , Tony Givargis , Alexandru Nicolau

Hyperspectral (HS) imaging presents itself as a non-contact, non-ionizing and non-invasive technique, proven to be suitable for medical diagnosis. However, the volume of information contained in these images makes difficult providing the…

Tuning searches are pivotal in High-Performance Computing (HPC), addressing complex optimization challenges in computational applications. The complexity arises not only from finely tuning parameters within routines but also potential…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-03-14 Adrian Perez Dieguez , Min Choi , Mahmut Okyay , Mauro Del Ben , Bryan M. Wong , Khaled Z. Ibrahim

Today's computing systems require moving data back-and-forth between computing resources (e.g., CPUs, GPUs, accelerators) and off-chip main memory so that computation can take place on the data. Unfortunately, this data movement is a major…

Hardware Architecture · Computer Science 2022-05-31 Geraldo F. Oliveira , Amirali Boroumand , Saugata Ghose , Juan Gómez-Luna , Onur Mutlu

Large-scale cloud security platforms must continuously query millions of structured cloud resource records distributed across thousands of tenant accounts. Broad, account-spanning queries saturate database infrastructure, producing P95…

Databases · Computer Science 2026-04-22 Prashant Kumar Pathak , Chandra Biksheswaran Mouleeswaran , Rama Teja Repaka

Reactive molecular dynamics simulations are computationally demanding. Reaching spatial and temporal scales where interesting scientific phenomena can be observed requires efficient and scalable implementations on modern hardware. In this…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-06-26 Hasan Metin Aktulga , Christopher Knight , Paul Coffman , Kurt A. O'Hearn , Tzu-Ray Shan , Wei Jiang

Most of the machine learning models have associated hyper-parameters along with their parameters. While the algorithm gives the solution for parameters, its utility for model performance is highly dependent on the choice of hyperparameters.…

Machine Learning · Computer Science 2022-01-19 Shashank Shekhar , Adesh Bansode , Asif Salim

Advances in bioinformatics are primarily due to new algorithms for processing diverse biological data sources. While sophisticated alignment algorithms have been pivotal in analyzing biological sequences, deep learning has substantially…

This paper proposes a novel higher-order multi-scale (HOMS) computational method, which is highly targeted for efficient, high-accuracy and low-computational-cost simulation of hygro-thermo-mechanical (H-T-M) coupling problems in…

Numerical Analysis · Mathematics 2025-12-11 Hao Dong , Yifei Ding , Jiale Linghu , Yufeng Nie , Yaochuang Han

Vector databases have rapidly grown in popularity, enabling efficient similarity search over data such as text, images, and video. They now play a central role in modern AI workflows, aiding large language models by grounding model outputs…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-17 Seth Ockerman , Amal Gueroudji , Song Young Oh , Robert Underwood , Nicholas Chia , Kyle Chard , Robert Ross , Shivaram Venkataraman

Proteomics is the large-scale analysis of the proteins. The common method for identifying proteins and characterising their amino acid sequences is to digest the proteins into peptides, analyse the peptides using mass spectrometry and…

Computational Engineering, Finance, and Science · Computer Science 2019-02-05 Samaneh Azari , Bing Xue , Mengjie Zhang , Lifeng Peng

The protein-protein interactions (PPIs) are crucial for understanding the majority of cellular processes. PPIs play important role in gene transcription regulation, cellular signaling, molecular basis of immune response and more. Moreover,…

Biomolecules · Quantitative Biology 2016-05-31 Maciej Pawel Ciemny , Mateusz Kurcinski , Andrzej Kolinski , Sebastian Kmiecik

Metabolomics complements investigation of the genome, transcriptome, and proteome of an organism. Today, the vast majority of metabolites remain unknown, in particular for non-model organisms. Mass spectrometry is one of the predominant…

Quantitative Methods · Quantitative Biology 2013-07-31 Kai Dührkop , Marcus Ludwig , Marvin Meusel , Sebastian Böcker