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Strong enhancement of molecular circular dichroism has the potential to enable efficient asymmetric photolysis, a method of chiral separation that has conventionally been impeded by insufficient yield and low enantiomeric excess. Here, we…

Silicon-based photonic biosensors, such as microring resonators and Mach-Zehnder interferometers, offer significant potential for the detection of analytes at low concentrations. To enhance response time and improve the limit of detection…

Optics · Physics 2024-07-01 Anders Henriksson , Peter Neubauer , Mario Birkholz

Silicon nanochannel field effect transistor (FET) biosensors are one of the most promising technologies in the development of highly sensitive and label-free analyte detection for cancer diagnostics. With their exceptional electrical…

Quantitative Methods · Quantitative Biology 2014-01-07 Pritiraj Mohanty , Yu Chen , Xihua Wang , Mi K. Hong , Carol L. Rosenberg , David T. Weaver , Shyamsunder Erramilli

Circular Dichroism (CD) can distinguish the handedness of chiral molecules. However, it is typically very weak due to vanishing absorption at low molecular concentrations. Here, we suggest Thermal Circular Dichroism (TCD) for chiral…

Optics · Physics 2024-07-19 Ershad Mohammadi , Giulia Tagliabue

We present the experimental realization of ordered arrays of hyper-doped silicon nanodisks, which exhibit a localized surface plasmon resonance. The plasmon is widely tunable in a spectral window between 2 and 5 $\mu$m by adjusting the free…

Optical metasurfaces with high-Q chiral resonances can boost light-matter interaction for various applications of chiral response for ultrathin, active, and nonlinear metadevices. Usually, such metasurfaces require sophisticated…

We present a guide for the design and fabrication of a CMOS-compatible metamaterial microstructure as an absorber of visible light with exceptionally high absorption efficiency (~ 98%), for wavelengths 400nm-700nm. The structural parameters…

Optics · Physics 2023-02-28 Vivek Khichar , Nader Hozhabri , Ali R. Koymen

Two-dimensional lattices of chiral nanoholes in a plasmonic film with lattice constants being slightly larger than light wavelength are proposed for effective control of polarization and spatial properties of light beams. Effective…

Mesoscale and Nanoscale Physics · Physics 2016-03-15 V. V. Klimov , I. V. Zabkov , A. A. Pavlov , R. -C. Shiu , H. -C. Chan , G. Y. Guo

Infrared spectroscopy is the technique of choice for chemical identification of biomolecules through their vibrational fingerprints. However, infrared light interacts poorly with nanometric size molecules. Here, we exploit the unique…

Biosensing based on whispering-gallery mode (WGM) resonators has been continuously studied with great attention due to its excellent sensitivity guaranteeing the label-free detection. However, its practical impact is insignificant to date…

Applied Physics · Physics 2020-01-08 Yeseul Kim , Hansuek Lee

In this thesis various plasmonic materials, such as hyperbolic metamaterial nanohole arrays and Au-coated free standing nanoassembly supporting nanopores, are investigated with the aim to perform optical sensing of DNA molecules with…

Optics · Physics 2022-11-14 Marzia Iarossi

Chirality is a fundamental feature in all domains of nature, ranging from particle physics over electromagnetism to chemistry and biology. Chiral objects lack a mirror plane and inversion symmetry and therefore cannot be spatially aligned…

Biosensors are an essential tool for medical diagnostics, environmental monitoring and food safety. Typically, biosensors are designed to detect specific analytes through functionalization with the appropriate capture agents. However, the…

Medical Physics · Physics 2023-09-26 Simon J. Ward , Tengfei Cao , Xiang Zhou , Catie Chang , Sharon M. Weiss

We present a detailed investigation of the near-field optical response of core-shell nanoparticles using Fourier-demodulated full-wave simulations, revealing significant modifications to established contrast mechanisms in scattering-type…

We report on the efficient design and fabrication of polymeric microracetrack optical resonators for label-free biosensing purposes. Vertically-coupled microresonators immersed in deionised water display high Q-factors (>35000) and finesses…

A conformal coating technique with nanocarbon was developed to enhance the surface properties of alumina nanoparticles for bio-applications. The ultra-thin carbon layer induces new surface properties such as water dispersion,…

Materials Science · Physics 2017-07-04 Morteza Aramesh , Phong A. Tran , Kostya Ostrikov , Steven Prawer

Recent advances in the physics of resonant optical metasurfaces allowed to realize the so-called maximum chirality of planar structures by engineering their geometric parameters. Here we employ bilayer membrane metasurfaces with a square…

Optics · Physics 2025-07-25 Brijesh Kumar , Ivan Toftul , Anshuman Kumar , Maxim Gorkunov , Yuri Kivshar

Sensing and discriminating between enantiomers of chiral molecules remains a significant challenge in the design of sensor platforms. In the case of chemoresistive sensors, where detection relies on changes in electrical response upon…

Optical fiber sensing carries a number of potential advantages for diagnostics and biomarker detection and monitoring, yet particular challenges persist in linking molecular recognition events to a change in the refractive index. DNA…

We present a rigorous finite element method to calculate circular dichroism (CD) in various systems consisting of nanostructures and oriented chiral molecules with electric quadrupole transitions. The interaction between oriented molecule…

Optics · Physics 2017-12-27 Weixuan Zhang , Tong Wu , Rongyao Wang , Xiangdong Zhang