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Identifying new disease-related patterns in medical imaging data with the help of machine learning enlarges the vocabulary of recognizable findings. This supports diagnostic and prognostic assessment. However, image appearance varies not…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Jeanny Pan , Philipp Seeböck , Christoph Fürböck , Svitlana Pochepnia , Jennifer Straub , Lucian Beer , Helmut Prosch , Georg Langs

The detection of nuclei is one of the most fundamental components of computational pathology. Current state-of-the-art methods are based on deep learning, with the prerequisite that extensive labeled datasets are available. The increasing…

Image and Video Processing · Electrical Eng. & Systems 2019-07-11 Nicolas Brieu , Armin Meier , Ansh Kapil , Ralf Schoenmeyer , Christos G. Gavriel , Peter D. Caie , Günter Schmidt

We propose an exhaustive methodology that leverages all levels of feature abstraction, targeting an enhancement in the generalizability of image classification to unobserved hospitals. Our approach incorporates augmentation-based…

Computer Vision and Pattern Recognition · Computer Science 2023-08-10 Milad Sikaroudi , Maryam Hosseini , Shahryar Rahnamayan , H. R. Tizhoosh

In computational pathology, deep learning (DL) models for tasks such as segmentation or tissue classification are known to suffer from domain shifts due to different staining techniques. Stain adaptation aims to reduce the generalization…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Daniel Reisenbüchler , Lucas Luttner , Nadine S. Schaadt , Friedrich Feuerhake , Dorit Merhof

The deployment of autonomous agents in real-world scenarios is challenged by "unknown unknowns", i.e. novel unexpected environments not encountered during training, such as degraded signs. While existing research focuses on anomaly…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Abhibha Gupta , Rully Agus Hendrawan , Mansur Arief

Preparing and scanning histopathology slides consists of several steps, each with a multitude of parameters. The parameters can vary between pathology labs and within the same lab over time, resulting in significant variability of the…

Computer Vision and Pattern Recognition · Computer Science 2018-01-11 Maxime W. Lafarge , Josien P. W. Pluim , Koen A. J. Eppenhof , Pim Moeskops , Mitko Veta

Recent research has investigated the shape and texture biases of deep neural networks (DNNs) in image classification which influence their generalization capabilities and robustness. It has been shown that, in comparison to regular DNN…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Ben Hamscher , Edgar Heinert , Annika Mütze , Kira Maag , Matthias Rottmann

Change detection has essential significance for the region's development, in which pseudo-changes between bitemporal images induced by imaging environmental factors are key challenges. Existing transformation-based methods regard…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Qi Zang , Shuang Wang , Dong Zhao , Dou Quan , Yang Hu , Licheng Jiao

Domain shift in digital histopathology can occur when different stains or scanners are used, during stain translation, etc. A deep neural network trained on source data may not generalise well to data that has undergone some domain shift.…

Image and Video Processing · Electrical Eng. & Systems 2022-05-10 Zeeshan Nisar , Jelica Vasiljević , Pierre Gançarski , Thomas Lampert

Deep learning models that are trained on histopathological images obtained from a single lab and/or scanner give poor inference performance on images obtained from another scanner/lab with a different staining protocol. In recent years,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-07 Harshal Nishar , Nikhil Chavanke , Nitin Singhal

Recent advances in deep learning for medical image segmentation demonstrate expert-level accuracy. However, in clinically realistic environments, such methods have marginal performance due to differences in image domains, including…

Computer Vision and Pattern Recognition · Computer Science 2019-06-13 Ling Zhang , Xiaosong Wang , Dong Yang , Thomas Sanford , Stephanie Harmon , Baris Turkbey , Holger Roth , Andriy Myronenko , Daguang Xu , Ziyue Xu

Data-driven techniques for machine vision heavily depend on the training data to sufficiently resemble the data occurring during test and application. However, in practice unknown distortion can lead to a domain gap between training and…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Maximiliane Gruber , Fabian Brand , Alina Mosebach , Jürgen Seiler , André Kaup

The lack of well-annotated datasets in computational pathology (CPath) obstructs the application of deep learning techniques for classifying medical images. %Since pathologist time is expensive, dataset curation is intrinsically difficult.…

Image and Video Processing · Electrical Eng. & Systems 2022-01-28 Ryan Zhang , Jiadai Zhu , Stephen Yang , Mahdi S. Hosseini , Angelo Genovese , Lina Chen , Corwyn Rowsell , Savvas Damaskinos , Sonal Varma , Konstantinos N. Plataniotis

Deep learning (DL)-based models have demonstrated good performance in medical image segmentation. However, the models trained on a known dataset often fail when performed on an unseen dataset collected from different centers, vendors and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Lei Li , Veronika A. Zimmer , Wangbin Ding , Fuping Wu , Liqin Huang , Julia A. Schnabel , Xiahai Zhuang

In this paper, we consider the problem of domain generalization in semantic segmentation, which aims to learn a robust model using only labeled synthetic (source) data. The model is expected to perform well on unseen real (target) domains.…

Computer Vision and Pattern Recognition · Computer Science 2022-10-14 Zhun Zhong , Yuyang Zhao , Gim Hee Lee , Nicu Sebe

Image style transfer has attracted widespread attention in the past few years. Despite its remarkable results, it requires additional style images available as references, making it less flexible and inconvenient. Using text is the most…

Computer Vision and Pattern Recognition · Computer Science 2024-12-09 Zhi-Song Liu , Li-Wen Wang , Jun Xiao , Vicky Kalogeiton

Convolutional Neural Networks (CNNs) often fail to maintain their performance when they confront new test domains, which is known as the problem of domain shift. Recent studies suggest that one of the main causes of this problem is CNNs'…

Computer Vision and Pattern Recognition · Computer Science 2021-04-02 Hyeonseob Nam , HyunJae Lee , Jongchan Park , Wonjun Yoon , Donggeun Yoo

Computational pathology, integrating computational methods and digital imaging, has shown to be effective in advancing disease diagnosis and prognosis. In recent years, the development of machine learning and deep learning has greatly…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Jiamu Wang , Chang-Su Kim , Jin Tae Kwak

Background and objectives. Domain shift is a generalisation problem of machine learning models that occurs when the data distribution of the training set is different to the data distribution encountered by the model when it is deployed.…

Computer Vision and Pattern Recognition · Computer Science 2022-07-28 Manuel García-Domínguez , César Domínguez , Jónathan Heras , Eloy Mata , Vico Pascual

Disentangled representation is a powerful technique to tackle domain shift problem in medical image analysis in unsupervised domain adaptation setting.However, previous methods only focus on exacting domain-invariant feature and ignore…

Image and Video Processing · Electrical Eng. & Systems 2023-03-07 Shuai Wang , Rui Li