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X-ray spectra of galaxy clusters are dominated by the thermal emission from the hot intracluster medium. In some cases, besides the thermal component, spectral models require additional components associated, e.g., with resonant scattering…

High Energy Astrophysical Phenomena · Physics 2018-11-07 Liyi Gu , Irina Zhuravleva , Eugene Churazov , Frits Paerels , Jelle Kaastra , Hiroya Yamaguchi

In this review we briefly summarize the recent developments in the research on Gamma-Ray Bursts, and discuss in more details the recent results derived from X-ray spectroscopy, in particular the detection of X-ray narrow features and their…

Astrophysics · Physics 2009-11-10 Luigi Piro

Absorption spectroscopy is a fundamental tool for probing molecular structure. However, performing absorption spectroscopy on individual molecules is challenging due to the low signal-to-noise ratio. Here, we report on a nondestructive…

Interferometric scattering microscopy has been a very promising technology for highly sensitive label-free imaging of a broad spectrum of biological nanoparticles from proteins to viruses in a high-throughput manner. Although it can reveal…

Optics · Physics 2021-08-11 Celalettin Yurdakul , Haonan Zong , Yeran Bai , Ji-Xin Cheng , M. Selim Unlu

Motivation. Cancer heterogeneity is observed at multiple biological levels. To improve our understanding of these differences and their relevance in medicine, approaches to link organ- and tissue-level information from diagnostic images and…

Quantitative Methods · Quantitative Biology 2020-05-19 Nova F. Smedley , Suzie El-Saden , William Hsu

We study an inverse problem where an unknown radiating source is observed with collimated detectors along a single line and the medium has a known attenuation. The research is motivated by applications in SPECT and beam hardening. If…

Functional Analysis · Mathematics 2020-11-10 Tommi Brander , Joonas Ilmavirta , Petteri Piiroinen , Teemu Tyni

Mid-infrared spectroscopy offers powerful label-free molecular analysis capabilities but faces significant challenges when analyzing complex biological samples. Here, we present a transformative surface-enhanced infrared absorption…

The early detection of cancer is a challenging problem in medicine. The blood sera of cancer patients are enriched with heterogeneous secretory lipid bound extracellular vesicles (EVs), which present a complex repertoire of information and…

Other Quantitative Biology · Quantitative Biology 2022-02-15 Abicumaran Uthamacumaran , Samir Elouatik , Mohamed Abdouh , Michael Berteau-Rainville , Zu-hua Gao , Goffredo Arena

Machine learning has emerged as an invaluable tool in many research areas. In the present work, we harness this power to predict highly accurate molecular infrared spectra with unprecedented computational efficiency. To account for…

Chemical Physics · Physics 2021-03-16 Michael Gastegger , Jörg Behler , Philipp Marquetand

Sensitive measurements of the linearly polarized spectra of stars can be used to deduce geometric properties of their otherwise unresolved circumstellar environments. This paper describes some of the evidence for optical pumping and…

Solar and Stellar Astrophysics · Physics 2015-03-17 J. R. Kuhn , B Geiss , D. M. Harrington

We present a system for molecular spectroscopy using a broadband mid-infrared laser with near infrared detection. Difference frequency generation of a Yb:fiber femtosecond laser produced a mid-infrared (MIR) source tunable from 2100-3700…

Optics · Physics 2015-05-30 Todd A. Johnson , Scott A. Diddams

In this paper we propose a new approach to identify melanoma diseases by identifying the distribution of its main skin chromophores (melanin, oxyhemoglobin and deoxyhemoglobin) from multispectral dermatological images. Based on Blind Source…

Medical Physics · Physics 2023-09-22 Mustapha Zokay , Hicham Saylani

We present ultra-fast quantum chemical methods for the calculation of infrared and ultraviolet-visible spectra designed to provide fingerprint information during autonomous and interactive explorations of molecular structures.…

Chemical Physics · Physics 2022-08-30 Francesco Bosia , Thomas Weymuth , Markus Reiher

Contrary to what might be expected, when an organic dye is sputtered onto an opaque holey metal film, transmission bands can be observed at the absorption energies of the molecules. This phenomenon, known as absorption-induced transparency,…

Mesoscale and Nanoscale Physics · Physics 2016-02-10 Sergio G. Rodrigo , L. Martín-Moreno

We demonstrate a new scheme of infrared spectroscopy with visible light sources and detectors. The technique relies on the nonlinear interference of correlated photons, produced via spontaneous parametric down conversion in a nonlinear…

Accurately and efficiently predicting the infrared (IR) spectra of a molecule can provide insights into the structure-properties relationships of molecular species, which has led to a proliferation of machine learning tools designed for…

The annotation of disease severity for medical image datasets often relies on collaborative decisions from multiple human graders. The intra-observer variability derived from individual differences always persists in this process, yet the…

Computer Vision and Pattern Recognition · Computer Science 2022-05-03 Chi Liu , Zongyuan Ge , Mingguang He , Xiaotong Han

Nuclear Magnetic Resonance (NMR) spectrometry uses electro-frequency pulses to probe the resonance of a compound's nucleus, which is then analyzed to determine its structure. The acquisition time of high-resolution NMR spectra remains a…

Infrared spectroscopy in the mid- and far-infrared provides powerful diagnostics for studying the emission regions in active galaxies. The large variety of ionic fine structure lines can probe gas conditions in a variety of physical…

Astrophysics · Physics 2007-09-27 Luigi Spinoglio

The imaging community has increasingly adopted machine learning (ML) methods to provide individualized imaging signatures related to disease diagnosis, prognosis, and response to treatment. Clinical neuroscience and cancer imaging have been…