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Full Waveform Inversion (FWI) stands as a nonlinear, high-resolution technology for subsurface imaging via surface-recorded data. This paper introduces an augmented Lagrangian dual formulation for FWI, rooted in the viewpoint that Lagrange…
Ultrasound video-based breast lesion segmentation provides a valuable assistance in early breast lesion detection and treatment. However, existing works mainly focus on lesion segmentation based on ultrasound breast images which usually can…
Tissue mechanics--stiffness, density and impedance contrast--are broadly informative biomarkers across diseases, yet routine CT, MRI, and B-mode ultrasound rarely quantify them directly. While ultrasound tomography (UT) is intrinsically…
Full waveform inversion (FWI) is a powerful tool for reconstructing material fields based on sparsely measured data obtained by wave propagation. For specific problems, discretizing the material field with a neural network (NN) improves the…
Recent ultrasound imaging modalities based on ultrasound computed tomography indicate a huge potential to detect pathologies is tissue due to altered biomechanical properties. Especially the imaging of speed-of-sound (SoS) distribution in…
Full-waveform inversion (FWI) is an advanced technique for reconstructing high-resolution subsurface physical parameters by progressively minimizing the discrepancy between observed and predicted seismic data. However, conventional FWI…
For 3D spatial transcriptomics (ST), the high per-section acquisition cost of fully sampling every tissue section remains a significant challenge. Although recent approaches predict gene expression from histology images, these methods…
Accurate and efficient simulation of wave equations is crucial in computational wave imaging applications, such as ultrasound computed tomography (USCT), which reconstructs tissue material properties from observed scattered waves.…
Edema is a potential indicator of underlying pathological changes. However, its low-contrast signature is often masked in conventional B-mode imaging by strong scatterers, making reliable detection challenging. Ultrasound (US) provides a…
Breast cancer is one of the most common causes of death among women worldwide. Early detection helps in reducing the number of deaths. Automated 3D Breast Ultrasound (ABUS) is a newer approach for breast screening, which has many advantages…
Background: Apparent Diffusion Coefficient (ADC) values and Total Diffusion Volume (TDV) from Whole-body diffusion-weighted MRI (WB-DWI) are recognized cancer imaging biomarkers. However, manual disease delineation for ADC and TDV…
The effective utilization of observational data is frequently hindered by insufficient resolution. To address this problem, we present a new spatio-temporal super-resolution (STSR) model, called InWaveSR. It is built on a deep learning…
Sound speed heterogeneities can create aberrations in B-mode ultrasound images by inducing tissue-dependent delays and diffractive effects that conventional beamforming does not incorporate. By using the Fourier split-step method to…
We consider the high-resolution seismic imaging method called full-waveform inversion (FWI). FWI is a data fitting method aimed at inverting for subsurface mechanical parameters. Despite the large adoption of FWI by the academic and…
Ultrasound brain imaging remains challenging due to the large difference in sound speed between the skull and brain tissues and the difficulty of coupling large probes to the skull. This work aims to achieve quantitative transcranial…
Accurate tumor segmentation and classification in breast ultrasound (BUS) imaging remain challenging due to low contrast, speckle noise, and diverse lesion morphology. This study presents a multi-task deep learning framework that jointly…
PDE-constrained optimization problems are often treated using the reduced formulation where the PDE constraints are eliminated. This approach is known to be more computationally feasible than other alternatives at large scales. However, the…
Practical applications of thermoacoustic tomography require numerical inversion of the spherical mean Radon transform with the centers of integration spheres occupying an open surface. Solution of this problem is needed (both in 2-D and…
Background: Multiparametric breast MRI data might improve tumor diagnostics, characterization, and treatment planning. Accurate alignment and delineation of images acquired at different field strengths such as 3T and 7T, remain challenging…
A novel and highly efficient computational framework for reconstructing binary-type images suitable for models of various complexity seen in diverse biomedical applications is developed and validated. Efficiency in computational speed and…