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The RefleXion X1 is the first biology-guided radiotherapy (BgRT) system. Its dual 90-degree PET detector collects fewer pair production events compared to a full-ring diagnostic PET system. In the proposed BgRT workflow, a short scan is…

Compact gamma cameras with a square-shaped monolithic scintillator crystal and an array of silicon photomultipliers (SiPMs) are actively being developed for applications in areas such as small animal imaging, cancer diagnostics and…

Medical Physics · Physics 2017-04-26 A. Morozov , F. Alves , J. Marcos , R. Martins , L. Pereira , V. Solovov , V. Chepel

Positronium-based imaging requires realistic modelling of positronium (Ps) decay in matter. We introduce a modular Ps decay model implemented in GATE 9.4 and GATE 10, enabling the definition of an arbitrary number of decay channels…

Proton therapy's full potential is limited by uncertainties that prevent optimal dose distribution. Monitoring techniques can reduce these uncertainties and enable adaptive treatment planning. Spatiotemporal Emission Reconstruction from…

Dual energy computed tomography (DECT) imaging plays an important role in advanced imaging applications due to its material decomposition capability. Image-domain decomposition operates directly on CT images using linear matrix inversion,…

Image and Video Processing · Electrical Eng. & Systems 2019-08-20 Zhipeng Li , Saiprasad Ravishankar , Yong Long , Jeffrey A. Fessler

Positron Emission Tomography using 2-[18F]-2deoxy-D-glucose as radiotracer (FDG-PET) is currently one of the most frequently applied functional imaging methods in clinical applications. The interpretation of FDG-PET data requires…

Tissues and Organs · Quantitative Biology 2020-01-22 Michele Piana , Giacomo Caviglia , Sara Sommariva

Positron emission tomography (PET) suffers from severe resolution limitations which limit its quantitative accuracy. In this paper, we present a super-resolution (SR) imaging technique for PET based on convolutional neural networks (CNNs).…

Image and Video Processing · Electrical Eng. & Systems 2021-07-29 Tzu-An Song , Samadrita Roy Chowdhury , Fan Yang , Joyita Dutta

This paper reviewed the machine learning-based studies for quantitative positron emission tomography (PET). Specifically, we summarized the recent developments of machine learning-based methods in PET attenuation correction and low-count…

Image and Video Processing · Electrical Eng. & Systems 2020-01-22 Tonghe Wang , Yang Lei , Yabo Fu , Walter J. Curran , Tian Liu , Xiaofeng Yang

The modern imaging techniques of Positron Emission Tomography and of Single Photon Emission Computed Tomography are not only two of the most important tools for studying the functional characteristics of the brain, but they now also play a…

Medical Physics · Physics 2007-05-23 A. S. Fokas , A. Iserles , V. Marinakis

Image quality of PET reconstructions is degraded by subject motion occurring during the acquisition. MR-based motion correction approaches have been studied for PET/MR scanners and have been successful at capturing regular motion patterns,…

This study introduces a novel framework for joint reconstruction of the activity and the attenuation (JRAA) in positron emission tomography (PET) using diffusion posterior sampling (DPS). By leveraging diffusion models (DMs), this approach…

A mini-PET style detector system is being developed for a plant imaging application with a compact array of silicon photomultipliers (SiPM) replacing position sensitive photomultipliers (PSPMT). In addition to compactness, the use of SiPMs…

Implicit neural representations (INRs) have demonstrated strong capabilities in various medical imaging tasks, such as denoising, registration, and segmentation, by representing images as continuous functions, allowing complex details to be…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Younès Moussaoui , Diana Mateus , Nasrin Taheri , Saïd Moussaoui , Thomas Carlier , Simon Stute

In computed tomography (CT) reconstruction, scattering causes server quality degradation of the reconstructed CT images by introducing streaks and cupping artifacts which reduce the detectability of low contrast objects. Monte Carlo (MC)…

Image and Video Processing · Electrical Eng. & Systems 2022-02-01 Ammar Alsaffar , Steffen Kieß , Kaicong Sun , Sven Simon

Low-dose positron emission tomography (PET) image reconstruction methods have potential to significantly improve PET as an imaging modality. Deep learning provides a promising means of incorporating prior information into the image…

Computer Vision and Pattern Recognition · Computer Science 2024-09-11 Cameron Dennis Pain , Yasmeen George , Alex Fornito , Gary Egan , Zhaolin Chen

Photoacoustic computed tomography (PACT) is an emerging computed imaging modality that exploits optical contrast and ultrasonic detection principles to form images of the absorbed optical energy density within tissue. When the imaging…

Medical Physics · Physics 2016-11-15 Qiwei Sheng , Kun Wang , Thomas P. Matthews , Jun Xia , Liren Zhu , Lihong V. Wang , Mark A. Anastasio

We propose a novel dynamic image reconstruction method from PET listmode data that could be particularly suited to tracking single or small numbers of cells. In contrast to conventional PET reconstruction our method combines the information…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Bernhard Schmitzer , Klaus P. Schäfers , Benedikt Wirth

Convergence of the block iterative method in image reconstruction for positron emission tomography (PET) requires careful control of relaxation parameters, which is a challenging task. The automatic determination of relaxation parameters…

Medical Physics · Physics 2025-01-15 Kibo Ote , Fumio Hashimoto , Yuya Onishi , Yasuomi Ouchi

We develop a positronium imaging method for the Jagiellonian PET (J-PET) scanners based on the time-of-flight maximum likelihood expectation maximisation (TOF MLEM). The system matrix elements are calculated on-the-fly for the coincidences…

Instrumentation and Detectors · Physics 2023-10-19 Roman Y. Shopa , Kamil Dulski

Uncompressed clinical data from modern positron emission tomography (PET) scanners are very large, exceeding 350 million data points (projection bins). The last decades have seen tremendous advancements in mathematical imaging tools many of…

Medical Physics · Physics 2020-01-08 Matthias J. Ehrhardt , Pawel Markiewicz , Carola-Bibiane Schönlieb