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The claims data, containing medical codes, services information, and incurred expenditure, can be a good resource for estimating an individual's health condition and medical risk level. In this study, we developed Transformer-based…

Machine Learning · Computer Science 2021-06-25 Xianlong Zeng , Simon Lin , Chang Liu

Deep autoencoder has been extensively used for anomaly detection. Training on the normal data, the autoencoder is expected to produce higher reconstruction error for the abnormal inputs than the normal ones, which is adopted as a criterion…

Computer Vision and Pattern Recognition · Computer Science 2019-08-07 Dong Gong , Lingqiao Liu , Vuong Le , Budhaditya Saha , Moussa Reda Mansour , Svetha Venkatesh , Anton van den Hengel

The increasing availability of electrocardiogram (ECG) data has motivated the use of data-driven models for automating various clinical tasks based on ECG data. The development of subject-specific models are limited by the cost and…

Machine Learning · Computer Science 2018-08-07 Prashnna K Gyawali , B. Milan Horacek , John L. Sapp , Linwei Wang

Simultaneous recordings from thousands of neurons across multiple brain areas reveal rich mixtures of activity that are shared between regions and dynamics that are unique to each region. Existing alignment or multi-view methods neglect…

Machine Learning · Computer Science 2025-10-24 Ram Dyuthi Sristi , Sowmya Manojna Narasimha , Jingya Huang , Alice Despatin , Simon Musall , Vikash Gilja , Gal Mishne

Generative AI framework-based modeling and prediction of longitudinal human brain images offer an efficient mechanism to track neurodegenerative progression, essential for the assessment of diseases like Alzheimer's. Among the existing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Ayantika Das , Keerthi Ram , Mohanasankar Sivaprakasam

Automatic diagnosis (AD), a critical application of AI in healthcare, employs machine learning techniques to assist doctors in gathering patient symptom information for precise disease diagnosis. The Transformer-based method utilizes an…

Computation and Language · Computer Science 2023-07-18 Huimin Wang , Wai-Chung Kwan , Kam-Fai Wong , Yefeng Zheng

Often the analysis of time-dependent chemical and biophysical systems produces high-dimensional time-series data for which it can be difficult to interpret which individual features are most salient. While recent work from our group and…

Accurate and robust drug response prediction is of utmost importance in precision medicine. Although many models have been developed to utilize the representations of drugs and cancer cell lines for predicting cancer drug responses (CDR),…

Quantitative Methods · Quantitative Biology 2023-11-22 Xiaoqiong Xia , Chaoyu Zhu , Yuqi Shan , Fan Zhong , Lei Liu

In the integrative analyses of omics data, it is often of interest to extract data representation from one data type that best reflect its relations with another data type. This task is traditionally fulfilled by linear methods such as…

Applications · Statistics 2021-03-30 Tianwei Yu

Integrating heterogeneous datasets across different measurement platforms is a fundamental challenge in many scientific applications. A common example arises in deconvolution problems, such as cell type deconvolution, where one aims to…

Methodology · Statistics 2025-09-30 Dongyue Xie , Lin Gui , Jingshu Wang

Human cancers present a significant public health challenge and require the discovery of novel drugs through translational research. Transcriptomics profiling data that describes molecular activities in tumors and cancer cell lines are…

This study presents Latent Diffusion Autoencoder (LDAE), a novel encoder-decoder diffusion-based framework for efficient and meaningful unsupervised learning in medical imaging, focusing on Alzheimer disease (AD) using brain MR from the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Gabriele Lozupone , Alessandro Bria , Francesco Fontanella , Frederick J. A. Meijer , Claudio De Stefano , Henkjan Huisman

Predicting the response of a cancer cell line to a therapeutic drug is pivotal for personalized medicine. Despite numerous deep learning methods that have been developed for drug response prediction, integrating diverse information about…

Machine Learning · Computer Science 2025-03-31 Haoyuan Shi , Tao Xu , Xiaodi Li , Qian Gao , Zhiwei Xiong , Junfeng Xia , Zhenyu Yue

Most of today's communication systems are designed to target reliable message recovery after receiving the entire encoded message (codeword). However, in many practical scenarios, the transmission process may be interrupted before receiving…

Information Theory · Computer Science 2023-02-01 Vukan Ninkovic , Dejan Vukobratovic , Christian Häger , Henk Wymeersch , Alexandre Graell i Amat

In recent years, there are numerous works been proposed to leverage the techniques of deep learning to improve social-aware recommendation performance. In most cases, it requires a larger number of data to train a robust deep learning…

Information Retrieval · Computer Science 2019-12-06 Yiteng Pan , Fazhi He , Haiping Yu

Continuous treatment effect estimation holds significant practical importance across various decision-making and assessment domains, such as healthcare and the military. However, current methods for estimating dose-response curves hinge on…

Machine Learning · Computer Science 2024-06-05 Ruijing Cui , Jianbin Sun , Bingyu He , Kewei Yang , Bingfeng Ge

This paper aims to improve the explainability of Autoencoder's (AE) predictions by proposing two explanation methods based on the mean and epistemic uncertainty of log-likelihood estimate, which naturally arise from the probabilistic…

Machine Learning · Computer Science 2021-10-20 Bang Xiang Yong , Alexandra Brintrup

Blind image quality assessment (BIQA) is a challenging problem with important real-world applications. Recent efforts attempting to exploit powerful representations by deep neural networks (DNN) are hindered by the lack of subjectively…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Zehong Zhou , Fei Zhou , Guoping Qiu

Variational Autoencoders (VAEs) provide a theoretically-backed and popular framework for deep generative models. However, learning a VAE from data poses still unanswered theoretical questions and considerable practical challenges. In this…

Machine Learning · Computer Science 2020-06-01 Partha Ghosh , Mehdi S. M. Sajjadi , Antonio Vergari , Michael Black , Bernhard Schölkopf

Enterprise relational databases increasingly contain vast amounts of non-semantic data - IP addresses, product identifiers, encoded keys, and timestamps - that challenge traditional semantic analysis. This paper introduces a novel…

Machine Learning · Computer Science 2025-11-12 Veera V S Bhargav Nunna , Shinae Kang , Zheyuan Zhou , Virginia Wang , Sucharitha Boinapally , Michael Foley