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DSC-MRI perfusion is a medical imaging technique for diagnosing and prognosing brain tumors and strokes. Its analysis relies on mathematical deconvolution, but noise or motion artifacts in a clinical environment can disrupt this process,…
Purpose: To develop a 3D distortion-free reduced-FOV diffusion-prepared GRE sequence and demonstrate its in-vivo application for diffusion imaging of the spinal cord in healthy volunteers. Methods: A 3D multi-shot reduced-FOV…
We present Distortion-Guided Restoration (DGR), a physics-informed hybrid CNN-diffusion framework for acquisition-free correction of severe susceptibility-induced distortions in prostate single-shot EPI diffusion-weighted imaging (DWI). DGR…
Pulsed-gradient spin-echo (PGSE) MRI experiments probe molecular self-diffusion through spin phase accumulation under time-dependent magnetic field gradients. For diffusion confined to cylindrical surfaces, existing analytical signal models…
Diffusion models have emerged as a promising class of generative models that map noisy inputs to realistic images. More recently, they have been employed to generate solutions to partial differential equations (PDEs). However, they still…
Preclinical diffusion MRI (dMRI) has proven value in methods development and validation, characterizing the biological basis of diffusion phenomena, and comparative anatomy. While dMRI enables in vivo non-invasive characterization of…
Diffusion models have recently gained popularity for accelerated MRI reconstruction due to their high sample quality. They can effectively serve as rich data priors while incorporating the forward model flexibly at inference time, and they…
Diffusion models generate data by learning to reverse a forward process, where samples are progressively perturbed with Gaussian noise according to a predefined noise schedule. From a geometric perspective, each noise schedule corresponds…
\hspace{2mm} Diffusion-weighted magnetic resonance imaging (dMRI) of the brain offers unique capabilities including noninvasive probing of tissue microstructure and structural connectivity. It is widely used for clinical assessment of…
Diffusion models with continuous stochastic differential equations (SDEs) have shown superior performances in image generation. It can serve as a deep generative prior to solving the inverse problem in magnetic resonance (MR)…
Diffusion models have shown remarkable promise for image restoration by leveraging powerful priors. Prominent methods typically frame the restoration problem within a Bayesian inference framework, which iteratively combines a denoising step…
Dynamic contrast-enhanced magnetic resonance imaging (DCE- MRI) is a widely used multi-phase technique routinely used in clinical practice. DCE and similar datasets of dynamic medical data tend to contain redundant information on the…
Purpose: Common to most MRSI techniques, the spatial resolution and the minimal scan duration of Deuterium Metabolic Imaging (DMI) are limited by the achievable SNR. This work presents a deep learning method for sensitivity enhancement of…
Multi-echo Gradient Echo (mGRE) sequences provide valuable quantitative parametric maps, such as Quantitative Susceptibility Mapping (QSM) and transverse relaxation rate (R2*), sensitive to tissue iron and myelin. However, structural…
Frequency-dependent diffusion MRI (dMRI) using oscillating gradient encoding and diffusion kurtosis imaging (DKI) techniques have been shown to provide additional insight into tissue microstructure compared to conventional dMRI. However, a…
Diffusion models, which convert noise into new data instances by learning to reverse a diffusion process, have become a cornerstone in contemporary generative modeling. In this work, we develop non-asymptotic convergence theory for a…
Reconstructing visual stimuli from functional Magnetic Resonance Imaging fMRI enables fine-grained retrieval of brain activity. However, the accurate reconstruction of diverse details, including structure, background, texture, color, and…
ECG-gated cine imaging in breath-hold enables high-quality diagnostics in most patients, arrhythmia and inability to hold breath, however, can severely corrupt outcomes. Real-time cardiac MRI in free-breathing leverages robust and faster…
Out-of-distribution (OOD) detection is a crucial part of deploying machine learning models safely. It has been extensively studied with a plethora of methods developed in the literature. This problem is tackled with an OOD score…
Diffusion MRI is a modern neuroimaging modality with a unique ability to acquire microstructural information by measuring water self-diffusion at the voxel level. However, it generates huge amounts of data, resulting from a large number of…