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Mutual Information (MI) is an useful tool for the recognition of mutual dependence berween data sets. Differen methods for the estimation of MI have been developed when both data sets are discrete or when both data sets are continuous. The…

Applications · Statistics 2017-08-30 Miguel A. Ré , Guillermo G. Aguirre Varela

Mutual information between two random variables is a well-studied notion, whose understanding is fairly complete. Mutual information between one random variable and a pair of other random variables, however, is a far more involved notion.…

Information Theory · Computer Science 2026-05-05 Aobo Lyu , Andrew Clark , Netanel Raviv

Codifying memories is one of the fundamental problems of modern Neuroscience. The functional mechanisms behind this phenomenon remain largely unknown. Experimental evidence suggests that some of the memory functions are performed by…

Neurons and Cognition · Quantitative Biology 2022-05-17 Ivan Y. Tyukin , Alexander N. Gorban , Carlos Calvo , Julia Makarova , Valeri A. Makarov

Estimating Mutual Information (MI), a key measure of dependence of random quantities without specific modelling assumptions, is a challenging problem in high dimensions. We propose a novel mutual information estimator based on parametrizing…

Machine Learning · Statistics 2025-10-24 Haoran Ni , Martin Lotz

We establish the first known upper bound on the exact and Wyner's common information of $n$ continuous random variables in terms of the dual total correlation between them (which is a generalization of mutual information). In particular, we…

Information Theory · Computer Science 2018-12-11 Cheuk Ting Li , Abbas El Gamal

Stimulus dimensionality-reduction methods in neuroscience seek to identify a low-dimensional space of stimulus features that affect a neuron's probability of spiking. One popular method, known as maximally informative dimensions (MID), uses…

Neurons and Cognition · Quantitative Biology 2015-02-26 Ross S. Williamson , Maneesh Sahani , Jonathan W. Pillow

We present a new mixed integer formulation for the discrete informative path planning problem in random fields. The objective is to compute a budget constrained path while collecting measurements whose linear estimate results in minimum…

Systems and Control · Electrical Eng. & Systems 2022-04-21 Shamak Dutta , Nils Wilde , Stephen L. Smith

Inferring the causal direction and causal effect between two discrete random variables X and Y from a finite sample is often a crucial problem and a challenging task. However, if we have access to observational and interventional data, it…

Machine Learning · Statistics 2020-10-16 Peter Gmeiner

In the context of statistical learning, the Information Bottleneck method seeks a right balance between accuracy and generalization capability through a suitable tradeoff between compression complexity, measured by minimum description…

Information Theory · Computer Science 2021-02-16 Mohammad Mahdi Mahvari , Mari Kobayashi , Abdellatif Zaidi

We consider the optimization of an uncertain objective over continuous and multi-dimensional decision spaces in problems in which we are only provided with observational data. We propose a novel algorithmic framework that is tractable,…

Machine Learning · Statistics 2018-10-30 Dimitris Bertsimas , Christopher McCord

Causal inference across multiple data sources offers a promising avenue to enhance the generalizability and replicability of scientific findings. However, data integration methods for time-to-event outcomes, common in biomedical research,…

Methodology · Statistics 2025-05-16 Yi Liu , Alexander W. Levis , Ke Zhu , Shu Yang , Peter B. Gilbert , Larry Han

We provide a new information-theoretic generalization error bound that is exactly tight (i.e., matching even the constant) for the canonical quadratic Gaussian (location) problem. Most existing bounds are order-wise loose in this setting,…

Information Theory · Computer Science 2023-11-14 Ruida Zhou , Chao Tian , Tie Liu

Mutual information between particle positions before and after mixing provides a universal assumption-free measure of mixing efficiency at low Reynolds number which accounts for the kinematic reversibility of the Stokes equation. For a…

Statistical Mechanics · Physics 2025-06-19 Luca Cocconi , Yihong Shi , Andrej Vilfan

We study the estimation of causal estimand involving the joint distribution of treatment and control outcomes for a single unit. In typical causal inference settings, it is impossible to observe both outcomes simultaneously, which places…

Methodology · Statistics 2026-02-16 Sirui Lin , Zijun Gao , Jose Blanchet , Peter Glynn

This paper is about how to partition decision variables while decomposing a large-scale optimization problem for the best performance of distributed solution methods. Solving a large-scale optimization problem sequen- tially can be…

Optimization and Control · Mathematics 2017-10-26 Yuchen Zheng , Ilbin Lee , Nicoleta Serban

We study an information analogue of infinitely divisible probability distributions, where the i.i.d. sum is replaced by the joint distribution of an i.i.d. sequence. A random variable $X$ is called informationally infinitely divisible if,…

Information Theory · Computer Science 2023-07-19 Cheuk Ting Li

Graph neural networks are widely used for node classification, but they remain vulnerable to out-of-distribution (OOD) shifts in node features and graph structure. Prior work established that methods trained with standard supervised…

Machine Learning · Computer Science 2026-05-15 Danny Wang , Ruihong Qiu , Zi Huang

Quantifying the dependence between high-dimensional random variables is central to statistical learning and inference. Two classical methods are canonical correlation analysis (CCA), which identifies maximally correlated projected versions…

Machine Learning · Computer Science 2023-09-29 Dor Tsur , Ziv Goldfeld , Kristjan Greenewald

Striking progress has recently been made in understanding human cognition by analyzing how its neuronal underpinnings are engaged in different modes of information processing. Specifically, neural information can be decomposed into…

Neurons and Cognition · Quantitative Biology 2022-10-07 Alexandra M. Proca , Fernando E. Rosas , Andrea I. Luppi , Daniel Bor , Matthew Crosby , Pedro A. M. Mediano

We propose learning discrete structured representations from unlabeled data by maximizing the mutual information between a structured latent variable and a target variable. Calculating mutual information is intractable in this setting. Our…

Machine Learning · Computer Science 2020-07-17 Karl Stratos , Sam Wiseman